With the recent revolution in Molecular Biology and the deciphering of the Human Genome, understanding of the building blocks that comprise living systems has advanced rapidly. We have yet to understand, however, how the physical forces that animate life affect the synthesis, folding, assembly, and function of these molecular building blocks. We are equally uncertain as to how these building blocks interact dynamically to create coupled regulatory networks from which integrative biological behaviors emerge. Here we review recent advances in the field of biomechanics at the cellular and molecular levels, and set forth challenges confronting the field. Living systems work and move as multi-molecular collectives, and in order to understand key aspects of health and disease we must first be able to explain how physical forces and mechanical structures contribute to the active material properties of living cells and tissues, as well as how these forces impact information processing and cellular decision making. Such insights will no doubt inform basic biology and rational engineering of effective new approaches to clinical therapy.

Dennis Discher

Cheng Dong

Jeffrey J Fredberg

Farshid Guilak

Donald Ingber

Paul Janmey

Roger D Kamm

Geert W Schmid-Schönbein

Sheldon Weinbaum

Annals of biomedical engineering

ANNALS OF BIOMEDICAL ENGINEERING是生物医学工程学会的官方期刊，发表生物工程和生物医学工程主要领域的原创文章。 《年鉴》是一本跨学科的国际期刊，旨在突出解决生物和生物医学问题的综合方法。

The Annals of Biomedical Engineering is the official journal of the Biomedical Engineering Society, dedicated to publishing original research articles in the fields of bioengineering and biomedical engineering. This interdisciplinary international journal aims to highlight integrated approaches to solving biological and biomedical problems.

《Annals of Biomedical Engineering》是生物医学工程学会的官方期刊，专注于发表生物工程和生物医学工程领域的原创研究文章。这本跨学科的国际期刊旨在强调解决生物和生物医学问题的综合方法。

Annals of Biomedical Engineering

Ann Biomed Eng

Biomechanics: cell research and applications for the next decade.

Recent advances in the field of biomechanics at the cellular and molecular levels are reviewed, and challenges confronting the field are set forth.

Category	Quartile
医学	2
医学, 工程生物医学	3

Biomechanics: cell research and applications for the next decade.

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info