The structural development of the heart depends heavily on mechanical forces, and rhythmic contractions generate essential physical stimuli during morphogenesis. Cardiac cells play a critical role in coordinating this process by sensing and responding to these mechanical forces. In vivo, cells experience rhythmic spatial and temporal variations in deformation-related stresses throughout heart development. What impact do these mechanical forces have on heart morphogenesis? Recent work in zebrafish (Danio rerio) offers important insights into this question. This review focuses on endocardial (EdCs) and myocardial cells (cardiomyocytes, CMs), key cell types in the heart, and provides a comprehensive overview of forces and tissue mechanics in zebrafish and their direct influence on cardiac cell identity.

Hajime Fukui

Renee Wei-Yan Chow

Choon Hwai Yap

Julien Vermot

Trends in Cell Biology

TRENDS IN CELL BIOLOGY 是分子和细胞生物学领域领先的评论期刊之一。每月发表的评论文章监控当前细胞生物学研究的广度和深度，及时报告新的发展，整合方法、学科和原则。所有文章均由顶尖科学家委托，然后经过严格的同行评审，确保平衡和准确性。除了评论之外，TRENDS IN CELL BIOLOGY 还发表意见文章，这些文章跟踪趋势并提供创新想法，以洞察新发展的影响并提出未来方向。

Trends in Cell Biology is one of the leading review journals in the field of molecular and cell biology. The journal publishes monthly review articles that monitor the breadth and depth of current research in cell biology, reporting new developments in a timely manner and integrating methods, disciplines, and principles. All articles are commissioned by top scientists and undergo rigorous peer review to ensure balance and accuracy. In addition to review articles, Trends in Cell Biology also publishes opinion pieces that track trends and provide innovative ideas to insightfully assess the impact of new developments and suggest future directions.

《Trends in Cell Biology》是分子和细胞生物学领域领先的评论期刊之一。该期刊每月发表的评论文章监测当前细胞生物学研究的广度和深度，及时报道新的发展，整合方法、学科和原则。所有文章均由顶尖科学家委托，并经过严格的同行评审，以确保内容的平衡和准确性。除了评论文章外，《Trends in Cell Biology》还发表意见文章，这些文章跟踪趋势并提供创新想法，以洞察新发展的影响并提出未来的研究方向。

Category	Quartile
生物学	1
生物学, 细胞生物学	2

Rhythmic forces shaping the zebrafish cardiac system

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