The norovirus (NoV), known for its high contagion rate, is the leading cause of acute gastroenteritis. The development of a NoV vaccine is hindered by significant antigenic variation, lack of suitable models, unknown vaccine protection duration, limited human challenge studies, complex performance patterns, and the absence of a reliable in vitro cultivation system, making prevention, early detection, and control the only effective measures to mitigate outbreaks. This review aims to discuss about several norovirus biosensor for point-of-care analysis. Several innovative biosensors have been developed, including techniques such as electrochemical NoV biosensors, colorimetric NoV biosensors, fluorescence NoV biosensors, CRISPR-based NoV biosensors, and other NoV biosensors. These approaches have detected norovirus in biological samples with high sensitivity and specificity. This biosensing technique holds significant promise, not only in improving the speed and accuracy of diagnostic processes but also in strengthening the global response to norovirus infections, thereby underscoring its pivotal role in public health and disease prevention.

David Septian Sumanto Marpaung

Ayu Oshin Yap Sinaga

Damayanti Damayanti

Analytical Biochemistry

该期刊的标题 ANALYTICAL BIOCHEMISTRY: METHODS IN THE BIOLOGICAL SCIENCES 宣布了其广泛的范围：基础生物科学的方法，包括生物化学、分子遗传学、细胞生物学、蛋白质组学、免疫学、生物信息学以及研究前沿领域的任何地方。重点是从严格分析到更准备的方法，包括蛋白质纯化的新方法以及细胞和器官培养的改进。实际技术同样具有包容性，从适体到酶学。该杂志特别活跃于： -生物分子的分析技术-适配体的选择和利用-生物传感器-色谱-克隆、测序和诱变-电化学方法-电泳-酶表征方法-免疫学方法-蛋白质和核酸的质谱法-代谢组学-纳米级技术-光谱学各种形式。该杂志不情愿T 包括大多数药物和严格的临床研究，因为这些类型的论文有更合适的发表平台。

The journal "Analytical Biochemistry" covers a wide range of methods in the biological sciences, including biochemistry, molecular genetics, cell biology, proteomics, immunology, and bioinformatics. The focus is on both rigorous analytical techniques and more practical methods, including new approaches to protein purification and improvements in cell and organ culture. The journal is inclusive of various practical techniques, from aptamers to enzymology. It particularly emphasizes the following areas: - Analytical techniques for biomolecules - Selection and application of aptamers - Biosensors - Chromatography - Cloning, sequencing, and mutagenesis - Electrochemical methods - Electrophoresis - Enzyme characterization methods - Immunological methods - Mass spectrometry for proteins and nucleic acids - Metabolomics - Nanoscale technologies - Various forms of spectroscopy. The journal is reluctant to include most drug-related and strictly clinical studies, as these types of papers are better suited for other publication platforms.

《Analytical Biochemistry》期刊涵盖了广泛的基础生物科学方法，包括生物化学、分子遗传学、细胞生物学、蛋白质组学、免疫学和生物信息学等领域。该期刊的重点在于从严格的分析方法到更为实用的技术，包括蛋白质纯化的新方法以及细胞和器官培养的改进。期刊内容涵盖多种实际技术，如适体、酶学等。该期刊特别关注以下领域：- 生物分子的分析技术 - 适配体的选择与应用 - 生物传感器 - 色谱 - 克隆、测序与诱变 - 电化学方法 - 电泳 - 酶表征方法 - 免疫学方法 - 蛋白质和核酸的质谱法 - 代谢组学 - 纳米技术 - 各种形式的光谱学。该期刊不接受大多数药物研究和严格的临床研究，因为这些类型的论文更适合在其他平台发表。

Category	Quartile
生物学	4
生物学, 分析化学	3
生物学, 生化研究方法	4
生物学, 生化与分子生物学	4

Norovirus Detection Technologies: From Conventional Methods to Innovative Biosensors

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