This article describes the rationale behind the use of systemically administered lidocaine as an analgesic. The analgesic efficacy of intravenously administered lidocaine is well documented by studies in human patients and laboratory animals. The mechanism by which systemically administered lidocaine produces analgesia is uncertain but is thought to include action at sodium, calcium, and potassium channels and the N-methyl-D-aspartate acid receptor. In addition, the anti-inflammatory actions of lidocaine are important in producing analgesia because inflammatory mediators augment neuronal excitability. The available studies of systemically administered lidocaine in horses provide evidence for the analgesic and anesthetic effects of intravenous lidocaine in this species.

Thomas J Doherty

M Reza Seddighi

The Veterinary clinics of North America. Equine practice

北美兽医诊所：EQUINE PRACTICE 为兽医领域的人们提供了最新的马匹治疗方法、最新进展的更新，并为选择治疗方案提供了良好的基础。每年出版 3 次，分别在 4 月、8 月和 12 月，每期都有专家、最先进的关于马实践中单个主题的评论，包括胃肠病学、影像学、传染病、营养学、骨科、病理学、药理学和治疗，和手术。

Veterinary Clinics of North America - Equine Practice provides veterinary professionals with the latest treatment methods and research advancements in equine care. The journal is published three times a year, in April, August, and December. Each issue features in-depth reviews by experts on specific topics in equine practice, including gastroenterology, imaging, infectious diseases, nutrition, orthopedics, pathology, pharmacology, therapy, and surgery.

《Veterinary Clinics of North America - Equine Practice》为兽医领域的专业人士提供最新的马匹治疗方法和研究进展。该期刊每年出版三期，分别在4月、8月和12月。每期都包含专家对马匹实践中某一特定主题的深入评论，涵盖胃肠病学、影像学、传染病、营养学、骨科、病理学、药理学、治疗和手术等领域。

Category	Quartile
农林科学	3
农林科学, 兽医学	3

Local anesthetics as pain therapy in horses.

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Journal Info

Category	Quartile
VETERINARY SCIENCES	3