ABSTRACT Objectives There is an increasing understanding of how trabecular bone adapts to biomechanical changes during ontogeny. However, limited research exists regarding the distal tibia, which is important in weight‐bearing locomotion as part of the ankle joint. This study aims to document the ontogenetic trabecular patterns of the distal tibia, in addition to changes in its structural heterogeneity. Materials and Methods Thirty‐eight distal tibiae, ranging in age from 28 intrauterine weeks to 8 postnatal years, from the Scheuer juvenile skeletal collection were examined. Trabecular bone was analyzed using a quantitative volume of interest approach and qualitative whole bone mapping following microcomputed tomography. Results Fetal and perinatal tibia lack mature organization and are associated with high bone volume fraction. During the first year of life, there is a decrease in bone volume fraction and an indication of early re‐organization of trabecular struts in the distal tibia. After one year of age, the distal tibia exhibits increased trabecular structural heterogeneity. Discussion The trabecular architecture of the fetal and perinatal distal tibia lacks mature organization and instead reflects ossification patterns. At these stages, there is a rapid accumulation of bone mass associated with gestational overproduction, hypothesized to be in preparation for subsequent postnatal changes. During the first year of life there is a decrease in volume fraction, associated with constructive regression. It is postulated this is related to changing biomechanical forces associated with the bipedal gait, in addition to growth demands. After one year of age, the distal tibia exhibits structural heterogeneity with trabecular adaption to accommodate specific bipedal stresses.

Rebecca A. G. Reid

Catriona Davies

Craig Cunningham

American Journal of Physical Anthropology

美国体质人类学杂志 (AJPA) 是美国体质人类学家协会的官方期刊。该杂志每月出版，每季度出版三卷。此外，每年还会出版两份增刊，即发表主要评论文章的《体质人类学年鉴》和《年会刊》，其中包含美国体质人类学家协会年会的科学计划以及海报和讲台的摘要演示文稿。 《体质人类学年鉴》有自己的编辑，由协会任命，独立于 AJPA 处理。按影响因子衡量，AJPA 是社会科学引文索引在人类学类别中列出的顶级期刊之一。 AJPA 作为体质人类学领先出版物的声誉建立在其在广泛主题中发表高质量科学文章的长达一个世纪的记录之上。

The American Journal of Physical Anthropology (AJPA) is the official journal of the American Association of Physical Anthropologists. It is published monthly, with three volumes released each quarter. Additionally, two supplements are published annually: the Annual Review of Physical Anthropology, which features major review articles, and the Annual Meeting Proceedings, which includes the scientific program of the American Association of Physical Anthropologists' annual meeting along with abstracts of poster and platform presentations. The Annual Review has its own editor, appointed by the association, and operates independently of AJPA. By impact factor, AJPA is one of the top-ranked journals in the anthropology category of the Social Sciences Citation Index. The reputation of AJPA as a leading publication in physical anthropology is built on a century-long record of publishing high-quality scientific articles on a wide range of topics.

《美国体质人类学杂志》（American Journal of Physical Anthropology，AJPA）是美国体质人类学家协会的官方期刊。该杂志每月出版，每季度发布三卷。此外，每年还会出版两份增刊，分别是发表主要评论文章的《体质人类学年鉴》和《年会刊》，其中包含美国体质人类学家协会年会的科学计划以及海报和讲台的摘要演示文稿。《体质人类学年鉴》由协会任命的独立编辑负责，独立于AJPA进行编辑。根据影响因子的评估，AJPA是社会科学引文索引在人类学类别中排名靠前的期刊之一。AJPA作为体质人类学领域的领先出版物，其声誉建立在一个世纪以来在广泛主题上发表高质量科学文章的基础上。

Category	Quartile
地球科学	2
地球科学, 人类学	2
地球科学, 进化生物学	4

Trabecular Bone Ontogeny of the Human Distal Tibia

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Journal Info

Category	Quartile
EVOLUTIONARY BIOLOGY	2