This study explored the fabrication of chitosan-polyethylene glycol-beeswax (CS-PEG-BW) as hydrogel dressings. Different formulation settings with varying BW concentrations were prepared to determine the influence of BW into the hydrophilicity, swellability, antibacterial, and hemocompatibility of the CS-PEG-BW network. Fourier transform infrared (FTIR) spectroscopy analysis of the samples confirmed the interactions brought by the positively charged CS and electronegative PEG. The emulsion of BW into the CS-PEG network made no significant changes on the hydrogel structure. In terms of the properties, the addition of BW showed improvements in the hydrophilicity, swellability, and antibacterial properties while the hemocompatibility property in terms of %Hemolysis remained almost equal to all the CS-PEG-BW hydrogels. The calculated surface free energy of the CS-PEG-BW showed increased polar groups of the hydrogel as BW concentration increased, leading to the improvement in the ionic sensitivity of the hydrogels during the swelling tests. Lastly, the presence of higher BW concentration showed better antibacterial activity against S. aureus. The resulting CS-PEG-BW hydrogels were found to be non-hemolytic substances that can hold moisture and inhibit bacterial growth. The study shows the potential of CS-PEG-BW hydrogel as wound dressings.

Jan Francois B. Severo

Joshua Kae B. Macugay

Erna Louise L. Elias

Vina B. Argayosa

Kathrina Lois M. Taaca

e-Journal of Surface Science and Nanotechnology

Our completely electronic and open-access journal aims at quick and versatile-style publication of research papers on fundamental theory and experiments at frontiers of science and technology relating to surfaces, interfaces, thin films, fine particles, nanowires, nanotubes, and other nanometer-scale structures, and their interdisciplinary areas such as crystal growth, vacuum technology, and so on. It covers their physics, chemistry, biology, materials science, and their applications to advanced technology for computations, communications, memory, catalysis, sensors, biological and medical purposes, energy and environmental problems, and so on.

The e-Journal of Surface Science and Nanotechnology is a fully electronic and open-access journal aimed at the rapid and versatile publication of research papers on fundamental theories and experiments at the forefront of science and technology related to surfaces, interfaces, thin films, fine particles, nanowires, nanotubes, and other nanometer-scale structures. It also covers interdisciplinary areas such as crystal growth and vacuum technology. The journal focuses on the physics, chemistry, biology, and materials science of these subjects, as well as their applications in advanced technologies for computation, communication, memory, catalysis, sensors, biological and medical purposes, and energy and environmental issues.

《e-Journal of Surface Science and Nanotechnology》是一本完全电子化和开放获取的期刊，旨在快速而多样化地发表关于表面、界面、薄膜、细颗粒、纳米线、纳米管及其他纳米级结构的基础理论和实验研究论文。期刊涵盖了与这些主题相关的跨学科领域，如晶体生长、真空技术等。我们关注这些领域的物理、化学、生物学、材料科学及其在计算、通信、存储、催化、传感器、生物医学、能源和环境问题等先进技术中的应用。

Synthesis and Evaluation of Chitosan-Polyethylene Glycol-based Hydrogel Loaded with Beeswax

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info

Category	Quartile
NANOSCIENCE & NANOTECHNOLOGY	4