The utilization of dodecaborate boron clusters, [B12X12]2− (X = Cl, Br, or I), as membrane carriers has been demonstrated recently, and their activity is known to be due to their superchaotropic nature. In this work, the mono-alkylation of [B12Br11OH]2− to functionalize it with an aliphatic spacer was developed with a view to expanding the known chemical space of membrane carriers based on [B12Br12]2−. A new and improved facile route for the preparation of [B12Br11OH]2−, which is an important precursor to other [B12Br11OR]2− species, is reported. Various alkoxylated [B12Br11O(CH2)5Z]2− (Z = OH, N(CO)2C6H4, CN and N3) derivatives were prepared via a divergent synthesis based on [B12Br11O(CH2)5Br]2−. One of the newly synthesized compounds was utilized as a membrane carrier, and its impact on cell viability was examined.

Satoshi Yamamoto

Hibiki Nakamura

Yumiko K. Kawamura

Taro Kitazawa

Mutsumi Kimura

Yu Kitazawa

Chemistry

Chemistry—A European Journal is a truly international journal with top quality contributions (2017 ISI Impact Factor: 5.16). It publishes a wide range of outstanding Reviews, Minireviews, Concepts, Full Papers, and Communications from all areas of chemistry and related fields.

Chemistry (Switzerland) is a truly international journal that publishes high-quality contributions from all areas of chemistry and related fields (2017 ISI Impact Factor: 5.16). It features a wide range of outstanding Reviews, Minireviews, Concepts, Full Papers, and Communications.

《Chemistry (Switzerland)》是一份真正国际化的期刊，发表来自化学及相关领域的高质量研究成果（2017年ISI影响因子：5.16）。期刊涵盖广泛的内容，包括优秀的综述、迷你综述、概念文章、完整论文和通讯。

Alkoxy Substituted Brominated closo-Dodecaborates with Functionalized Aliphatic Spacers

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Journal Info

Category	Quartile
CHEMISTRY, MULTIDISCIPLINARY	3