Implantable medical devices have played a significant role in improving both medical care and patients' quality of life. Urinary Catheters (UCs) are commonly utilized as a substitute for bladder drainage and urine collection to prevent urinary retention in patients. However, bacterial colonization and biofilm formation on the catheter surface are prone to occur, leading to catheter-associated urinary tract infections (CAUTIs) and other complications. In recent years, UC coatings have garnered increasing attention. In this review, various antifouling and antibacterial materials for UC coatings are summarized and their impacts on bacterial activities are linked to potential mechanisms of action. Additionally, this review provides an in-depth understanding of the current advancements in UC coatings by presenting the advantages, limitations, notable achievements, and latest research findings. Finally, it anticipates the prospective design and development trajectories of UC coatings in this domain. This holds paramount significance in advancing medical device technology. STATEMENT OF SIGNIFICANCE: Combating catheter-associated urinary tract infections is a major healthcare challenge, and urinary catheter (UC) coatings are considered promising candidates to counter these infections. In this review, various antifouling and antibacterial materials for UCs are summarized, and their impacts on bacterial activities are linked to potential mechanisms of action. Additionally, the review provides an in-depth understanding of the current advancements in UC coatings by presenting the advantages, limitations, notable achievements, and latest research findings. This holds paramount significance in advancing medical device technology. This review not only contributes to the scientific research but also sparks interest among readerships and other researchers in the study of safer and more effective UC coatings for improved patient outcomes.

Qianwen Zhang

Qida Zong

Xinke Feng

Min Luo

Wei Sun

Yinglei Zhai

Acta Biomaterialia

ACTA BIOMATERIALIA 是 ELSEVIER 出版的月度同行评审科学期刊。它代表 ACTA MATERIALIA, INC. 出版，由 ASM INTERNATIONAL 和 THE MINERALS, METALS & MATERIALS SOCIETY 赞助。杂志创刊于2005年1月，主编为W.R. WAGNER（匹兹堡大学）。该杂志涵盖生物材料科学的研究，包括从宏观到纳米级的生物材料结构和功能的相互关系。专题报道包括生物医学和生物相容性材料。

Acta Biomaterialia is a monthly peer-reviewed scientific journal published by Elsevier. It is published on behalf of ACTA MATERIALIA, INC. and sponsored by ASM INTERNATIONAL and THE MINERALS, METALS & MATERIALS SOCIETY. The journal was established in January 2005, with W.R. WAGNER (University of Pittsburgh) as the editor-in-chief. It covers research in biomaterials science, focusing on the relationship between the structure and function of biomaterials at macro to nano scales. Topics include biomedical and biocompatible materials.

《Acta Biomaterialia》是由Elsevier出版的月度同行评审科学期刊。该期刊由ACTA MATERIALIA, INC.出版，并由ASM INTERNATIONAL和THE MINERALS, METALS & MATERIALS SOCIETY赞助。创刊于2005年1月，主编为W.R. WAGNER（匹兹堡大学）。期刊涵盖生物材料科学的研究，探讨生物材料的结构与功能之间的关系，范围从宏观到纳米级。专题报道包括生物医学和生物相容性材料。

Category	Quartile
医学	1
医学, 工程生物医学	1
医学, 材料科学生物材料	1

Antibacterial and antifouling materials for urinary catheter coatings

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