SUMMARY An estimated 750 million people are at risk of infections with food-borne trematodes, which comprise liver flukes ( Clonorchis sinensis , Fasciola gigantica , Fasciola hepatica , Opisthorchis felineus , and Opisthorchis viverrini ), lung flukes ( Paragonimus spp.), and intestinal flukes (e.g., Echinostoma spp., Fasciolopsis buski , and the heterophyids). Food-borne trematodiases pose a significant public health and economic problem, yet these diseases are often neglected. In this review, we summarize the taxonomy, morphology, and life cycle of food-borne trematodes. Estimates of the at-risk population and number of infections, geographic distribution, history, and ecological features of the major food-borne trematodes are reviewed. We summarize clinical manifestations, patterns of infection, and current means of diagnosis, treatment, and other control options. The changing epidemiological pattern and the rapid growth of aquaculture and food distribution networks are highlighted, as these developments might be associated with an elevated risk of transmission of food-borne trematodiases. Current research needs are emphasized.

Jennifer Keiser

Jürg Utzinger

Clinical Microbiology Reviews

临床微生物学评论 (CMR) 分析了临床微生物学和免疫学的最新发展，提供了该领域的当前知识状态，以及对有争议问题的平衡、发人深省的观点。

Clinical Microbiology Reviews analyzes the latest developments in clinical microbiology and immunology, providing the current state of knowledge in the field and offering balanced and thought-provoking perspectives on controversial issues.

《Clinical Microbiology Reviews》分析了临床微生物学和免疫学的最新发展，提供了该领域的当前知识状态，并对有争议的问题提出了平衡且发人深省的观点。

Food-Borne Trematodiases

The changing epidemiological pattern and the rapid growth of aquaculture and food distribution networks are highlighted, as these developments might be associated with an elevated risk of transmission of food-borne trematodiases.

Category	Quartile
医学	1
医学, 微生物学	1

Food-Borne Trematodiases

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