The search for novel image contrasts has been a major driving force in the magnetic resonance (MR) research community, in order to gain further information on the body’s physiological and pathological conditions. Chemical exchange saturation transfer (CEST) is a novel MR technique that enables imaging certain compounds at concentrations that are too low to impact the contrast of standard MR imaging and too low to directly be detected in MRS at typical water imaging resolution. For this to be possible, the target compound must be capable of exchanging protons with the surrounding water molecules. This property can be exploited to cause a continuous buildup of magnetic saturation of water, leading to greatly enhanced sensitivity. The goal of the present review is to introduce the basic principles of CEST imaging to the general molecular imaging community. Special focus has been given to the comparison of state-of-the-art CEST methods reported in the literature with their positron emission tomography (PET) counterparts.

B. Wu

G. Warnock

M. Zaiss

C. Lin

M. Chen

Z. Zhou

L. Mu

D. Nanz

R. Tuura

G. Delso

EJNMMI Physics

EJNMMI PHYSICS 是一个国际平台，面向对物理问题特别感兴趣的核医学科学家、用户和采用者。作为欧洲核医学和分子成像杂志的配套期刊，该杂志采用多学科方法，欢迎原创材料和研究，重点是应用物理学和数学以及核医学中的成像系统工程和原型设计。这包括物理驱动的方法或物理支持的算法，促进早期临床采用核医学成像和治疗。

EJNMMI Physics is an international platform aimed at nuclear medicine scientists, users, and practitioners with a particular interest in physical issues. As a companion journal to the European Journal of Nuclear Medicine and Molecular Imaging, it adopts a multidisciplinary approach, welcoming original materials and research that focus on applied physics and mathematics, as well as imaging system engineering and prototype design in nuclear medicine. This includes physics-driven methods or physics-supported algorithms that facilitate the early clinical adoption of nuclear medicine imaging and therapy.

EJNMMI Physics 是一个国际平台，专注于核医学科学家、用户和采用者对物理问题的兴趣。作为欧洲核医学和分子成像杂志的配套期刊，本杂志采用多学科的方法，欢迎原创研究和材料，重点关注应用物理学、数学以及核医学中的成像系统工程和原型设计。这包括物理驱动的方法或物理支持的算法，以促进核医学成像和治疗在早期临床中的应用。

EJNMMI Phys

An overview of CEST MRI for non-MR physicists

The goal of the present review is to introduce the basic principles of CEST imaging to the general molecular imaging community and comparison of state-of-the-art CEST methods reported in the literature with their positron emission tomography (PET) counterparts.

Category	Quartile
医学	2
医学, 核医学	2

An overview of CEST MRI for non-MR physicists

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Journal Info

Category	Quartile
RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING	2