ACTA OTO-LARYNGOLOGICA 是一本真正的国际化耳鼻喉科学和头颈外科杂志。该杂志发表了关于临床实践、临床研究和基础科学的前沿论文。 ACTA 还弥合了临床和基础研究之间的差距。

Acta Oto-Laryngologica is a truly international journal in the field of otolaryngology and head and neck surgery. The journal publishes cutting-edge papers on clinical practice, clinical research, and basic science, and it aims to bridge the gap between clinical and basic research.

《Acta Oto-Laryngologica》是一本真正国际化的耳鼻喉科学和头颈外科期刊。该期刊发表关于临床实践、临床研究和基础科学的前沿论文，并且致力于弥合临床与基础研究之间的差距。

Acta Oto-Laryngologica

Changes of regional cerebral blood flow (rCBF) in the auditory cortices induced by sound stimulation were examined in nine postlingually and five prelingually deaf cochlear implant (CI) users by 15O-labeled water Positron Emission Tomography, and the results were compared with those of eight normal volunteers. Speech stimulation caused significantly greater rCBF increase compared with noise stimulation in the auditory association area in normal and postlingually deaf subjects. In prelingually deaf subjects, however, speech activation of the auditory association area was much less than that found in either of the other two groups. Neuronal networks for speech sound processing in the auditory association area in postlingually deaf individuals are thought be similar to those in normal subjects, while those in prelingually deaf patients who received CI after the speech acquisition period may not develop completely.

Yasushi Naito

Shigeru Hirano

Iwao Honjo

Hidehiko Okazawa

Koichi Ishizu

Haruo Takahashi

Nobuya Fujiki

Yosaku Shiomi

Yoshiharu Yonekura

Junji Konishi

Sound-induced Activation of Auditory Cortices in Cochlear Implant Users with Post- and Prelingual Deafness Demonstrated by Positron Emission Tomography

正电子发射断层扫描显示人工耳蜗使用者在语前和语后聋中听觉皮层的声诱导激活

The etiology of motion sickness is now usually explained in terms of a qualitatively formulated "sensory conflict" hypothesis. By consideration of the information processing task faced by the central nervous system in estimating body spatial orientation and in controlling active body movement using an "internal model" referenced control strategy, a mathematical model for sensory conflict generation is developed. The model incorporates and extends models proposed by von Holst, Held, and Reason, and is congruent with multisensory models for spatial orientation developed by Young and coworkers. The model postulates a major dynamic functional role for sensory conflict signals in movement control, as well as in sensory-motor adaptation. It accounts for the role of active movement in creating motion sickness symptoms in some experimental circumstances, and in alleviating them in others. The relationship between motion sickness produced by "sensory rearrangement" and that resulting from external motion disturbances is explicitly defined. A nonlinear conflict averaging model is proposed which describes dynamic aspects of experimentally observed subjective discomfort sensation, and suggests resulting behaviours. The model admits several possibilities for adaptive mechanisms which do not involve internal model updating. Further systematic efforts to experimentally refine and validate the model are indicated.

Charles M. Oman

A Heuristic Mathematical Model for the Dynamics of Sensory Conflict and Motion Sickness

感觉冲突与运动病动力学的启发式数学模型

Introduction: We currently interpret the video Head Impulse Test (vHIT) results mainly based on the gain value.Aim: The purpose of this study is to evaluate vHIT results for both gain and re-fixation saccades on unilateral definite Meniere's disease (MD) subjects in comparison with normal healthy subjects.Materials and Methods: Forty unilateral definite MD subjects and age-matched healthy subjects were recruited. Pure tone audiometry, the caloric test, and the vHIT test were performed on MD subjects. The vHIT test was performed on healthy subjects.Results: The velocity regression gain (VRG) of the affected ear in patients with MD is significantly lower than of those in healthy subjects. The total percentage of refixation saccades is significantly higher in patients with MD when compared to healthy subjects. VRG values were not well-correlated with the percentage of refixation saccades. VRG asymmetry values are also not well-correlated with the percentage of unilateral canal weakness. A moderately stronger correlation between the percentage of refixation saccades and percentage of unilateral canal weakness, with an r2 of 0.474.Conclusions: The present study suggests that while VRGs are still a diagnostic parameter of detecting MD, the presence of refixation saccades can also have diagnostic value, especially with normal VRGs, in detecting MD.

Shreyas Bharadwaj

Michelle R. Petrak

Cammy M. Bahner

Laurin E. Sharp

Sara F. Mosey-Claycomb

Akihiro J. Matsuoka

Diagnostic value of refixation saccades in the Video Head Impulse Test (vHIT) in unilateral definite Meniere’s disease

单侧明确梅尼埃病中视频头脉冲试验（vHIT）中再注视扫视的诊断价值

Background: The caloric test has been used to evaluate the semi-circular canal function for decades. In 2009, the video head impulse test (vHIT) was introduced, which can be used to evaluate the semi-circular canal function within a short time. Although both tests examine the semi-circular canal, the stimulation methods differ and it is unclear whether the vHIT is equivocal to the caloric test.Aims/objectives: This study aimed to discern the differences between the vHIT and caloric test.Material and methods: This study comprised 112 patients with vertigo who visited the vertigo/dizziness centre at our university hospital. Each of these patients underwent a caloric test and vHIT within the same day, and their results were compared. Additionally, an electrocochleography (EcoG) examination, glycerol test (G test), and MRI (performed 4 h after an intravenous gadolinium injection) were conducted to evaluate the influence of endolymphatic hydrops (EH) on the caloric test and vHIT results.Results: Differences in the caloric test and vHIT results, among those with and without EH, were observed in 66.7 and 35.3% of patients, respectively.Conclusions and significance: EH resulted in a difference in results between the caloric test and vHIT. Activated hair cell type may also be implicated.

Masayuki Shugyo

Taeko Ito

Tomoyuki Shiozaki

Daisuke Nishikawa

Hiroki Ohyama

Hiroto Fujita

Toshiaki Yamanaka

Tadashi Kitahara

Comparison of the video head impulse test results with caloric test in patients with Meniere’s disease and other vestibular disorders

梅尼埃病与其他前庭疾病患者视频头脉冲试验与冷热试验结果的比较

Since the first descriptions of superior canal dehiscence (SCD) syndrome, it has been widely demonstrated how a bony defect overlying the superior semicircular canal (SSC) can result in a low-imped...

Andrea Castellucci

Salvatore Martellucci

Pasquale Malara

Cecilia Botti

Valeria Del Vecchio

Cristina Brandolini

Gian Gaetano Ferri

Angelo Ghidini

Enrico Armato

Possible pathomechanisms accounting for both sound/pressure-induced eye movements and video head impulse test data in superior canal dehiscence

可能解释上半规管裂中声音/压力诱发眼球运动和视频头脉冲测试数据的病理机制

Background Cochlear implants (CI) help regain perception of sound for patients with sensorineural hearing loss. The ability to recognize music pitch may be crucial for recognizing and producing speech for Mandarin.

Yunyi Lu

Yutong Wu

Dong Zeng

Chi Chen

Panpan Bian

Baicheng Xu

Music perception and its correlation with auditory speech perception in pediatric Mandarin-speaking cochlear implant users

音乐感知及其与听觉言语感知的关联性研究——以普通话儿童语后聋人工耳蜗使用者为例

Due to the therapeutic needs of inner ear diseases, a simple method of inner ear drug delivery has been under exploration. Postauricular administration, which involves injecting the drug through the middle of the retroauricular groove, is a potential novel approach, but its mechanisms remain unclear.

Nishan Chen

Tongxiang Diao

Jilei Zhang

Lisheng Yu

Ototoxic effects of unilateral postauricular neomycin administration on the inner ears of Guinea pigs

单侧耳后新霉素给药对豚鼠内耳的耳毒性效应

Background Recurrence rate of necrotising otitis externa (NOE) after treatment is 15-20%. This is mainly due to a lack of reliable clinical indicator for the resolution of disease.

Paul Zhaobo Liu

Dimitrios Spinos

Amr Allam

Patrick Long

Wai Sum Cho

Neil Fergie

C-reactive protein (CRP) and otorrhoea as prognosticate markers for necrotising otitis externa treatment response: based on a retrospective cohort study of 62 patients

C反应蛋白（CRP）和耳漏作为坏死性外耳炎治疗反应的预测标志物：基于62例患者的回顾性队列研究

Background Cholesteatoma is a proliferative disease that affects the tympanic cavity and temporal bone. Despite many studies and various theories, the etiopathogenesis of cholesteatoma has not been fully elucidated. Features such as invasion, migration, uncontrolled proliferation, and lack of differentiation are observed in both cholesteatoma and neoplasia.

Levent Şimşek

M. Selman Yıldırım

Çağatay Han Ülkü

Ayşe Gül Zamani

Somatic genetic alterations of oncogenes and tumor suppressor genes in cholesteatoma

胆脂瘤中癌基因和肿瘤抑制基因的体细胞遗传改变

Background Optimizing the educational experience of trainees in the operating room is important; however, ear anatomy and otologic surgery are challenging for trainees to grasp. Viewing otologic surgeries often involves limitations related to video quality, such as visual disturbances and instability.

Hye Ah Joo

Kanggil Park

Jun-Sik Kim

Young Hyun Yun

Dong Kyu Lee

Seung Cheol Ha

Namkug Kim

Jong Woo Chung

Artificial intelligence for optimizing otologic surgical video: effects of video inpainting and stabilization on microscopic view

人工智能优化耳科手术视频：视频修复与稳定对显微视野的影响

Abbreviation	Acta. Otolaryngol.
Journal Impact	1.32
Quartiles(Global)	OTORHINOLARYNGOLOGY(Q3)

ISSN	0001-6489, 1651-2251
h-index	90

Publication Information	Publisher: Informa Healthcare，Publishing cycle: Monthly，Journal Type: journal，Open Access Journals: No
Basic data	Year of publication: 1920，Proportion of original research papers: 99.04%，Self Citation Rate:8.30%， Gold OA Rate: 17.36%
Average review cycle	网友分享经验：一般,3-6周
Average recruitment ratio	网友分享经验：容易

Acta Oto-Laryngologica

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