Acta rheumatologica Scandinavica

Summary85 muscles, in 30 rheumatoid arthritis patients, were examined by EMG. The patients were subdivided into steroid and non-steroid treated groups.In both groups, the EMG demonstrated myopathic, polymyositic and neuropathic lesions, the first two predominating. Similar changes were found regardless of the size of the muscle examined. A relatively high number of myopathic changes were observed in early RA. The activity of the disease did not seem to play an important role. No correlation with the condition of the adjacent joint was found. No patient had a normal EMG in all the muscles examined. The conduction velocity indicated an entrapment syndrome in four patients. Creatine phosphokinase was normal in 23 patients, while aldolase was moderately high in 9 of 23 cases.

A. Magora

E. Wolf

B. Gonen

Acta Rheumatologica Scandinavica

Electrodiagnostic Investigation of the Neuromuscular Lesions in Rheumatoid Arthritis

类风湿关节炎神经肌肉病变的电诊断研究

SummaryThe muramidase activity of serum was studied in 27 cases of rheumatoid arthritis. The enzyme activity in rheumatoid serum (mean 11.0 μg./ml.) did not differ significantly from that in the 30 healthy controls (mean 9.4 μg./ml.). The muramidase activity in the synovial fluid of 36 rheumatoid arthritis patients was markedly elevated (mean 20.2 μg./ml.). In osteoarthritic synovial fluid (8 cases) the muramidase activity was low (mean 8.0 μg./ml.).No correlation was found between the total white blood count and the muramidase activity in rheumatoid synovial fluid. A positive relationship was observed between the enzyme activity and the total protein concentration. The elevated concentration of muramidase in synovial fluid of rheumatoid arthritis patients is interpreted as evidence of increased release of hydrolytic lysosomal enzymes. It remains to be shown which type of synovial fluid leukocytes produces the enzyme in question.

Martti Oka

Olavi Seppälä

Muramidase (Lysozyme) in Joint Fluid and Serum of Rheumatic Patients

风湿病患者关节液和血清中的溶菌酶（溶菌酶）

SummaryThe manubrio-sternal joints (MSJs) of 10 male and 10 female non-rheumatoid subjects and of 11 subjects with RA were studied. Microradiography often revealed herniation of the intra-articular fibrocartilaginous disc into the cancellous bone and osteo-arthritic changes. In RA, erosive destruction of the articular surfaces was seen in six cases and in one subject the joint was ankylotic. Histologically the MSJ presented degenerative phenomena but no inflammatory changes in old non-rheumatic subjects. Active inflammation was visible in four joints from rheumatoid subjects, and in another four fibrous replacement suggestive of earlier inflammation was seen. The joints from non-rheumatoid subjects presented a histological joint cavity in nine cases, with or without synovial-like cells lining the cavity. A similar cavity was present in only one of the joints taken from rheumatoid subjects and there were inflammatory changes in the synovial tissue in this joint. It is suggested that involvement of the MSJ in RA may be related to the occurrence of synovia in MSJ. It is also stated that similar roentgenological changes in MSJ may arise due to an inflammatory as well as due to a degenerative process.

Martti Kormano

A Microradiographic and Histological Study of the Manubrio-Sternal Joint in Rheumatoid Arthritis

类风湿关节炎中胸骨柄-胸骨关节的显微放射学和组织学研究

SummaryThe aim of the study was to find the most reliable and precise incidence of rheumatic fever attacks in the general population. All new cases of rheumatic fever were recorded in an area of 100,000 population. The frequency of first attacks and recurrences decreased from 53 per 100,000 inhabitants to 15 in 1968. Less pronounced was the fall in the incidence of first attacks. The prevalence of rheumatic heart diseases in the studied group of patients was relatively low.Epidemiological studies are one of the most important components of the surveillance of rheumatic fever. Further important tasks are early diagnosis and hospitalization, introduction of adequate therapy and (effective) prophylactic measures, with periodic checkups.

Stefan Sitaj

Tibor Urbánek

Karol Bošmanský

Some Aspects of Epidemiology and Surveillance of Rheumatic Fever

风湿热流行病学与监测的若干方面

Summary125I-labelled Urographin has been used intra-articularly as tracer and 60 per cent Urographin as contrast in ten knee joints of patients with classical rheumatoid arthritis. Nine traumatic knees served as controls. The rapid rate of disappearance of the contrast from joints with rheumatoid inflammation was higher than in controls. Over the rheumatoid joints the radioactivity had decreased to half the initial value in 2.85 hrs. and over the traumatic joints in 3.70 hrs. In the radiographs clear evidence of absorption of contrast by the synovial membrane, the hyaline cartilage and the fibrocartilaginous tissue of the menisci was demonstrated.In one case visual proof was obtained of drainage of the contrast through the local lymphatics. The series of arthrograms taken from this knee indicate that this drainage was rapid.

Rasmus Stenström

Otto Wegelius

Clearance of<sup>125</sup>I-Labelled Urographin from Knee Joints in Rheumatoid Arthritis

类风湿性关节炎膝关节中<sup>125</sup>I标记的优洛芬净清除率

SummaryOne autopsy case of ankylosing spondylitis was studied with histology, tetracycline bone labelling, microradiography and scanning electron microscopy. A focus of inflammatory cells was found beneath the anterior periost of a lumbar vertebral body and early marginal syndesmophytes were demonstrated by histology and microradiography. Tetracycline bone labelling showed new bone formation within osteophytes attempting to bridge an intervertebral facet joint. Scanning electron microscopy showed degeneration of femoral head articular cartilage while articular cartilage of an unfused portion of a sacro-iliac joint showed no definite changes with respect to equivalent controls.

H. Inoue

H. Julkunen

K. Vainio

Ankylosing Spondylitis: Report of one Case Studied with Histology, Tetracycline Bone Labelling, Microradiography and Scanning Electron Microscopy

强直性脊柱炎：一例病例研究，涉及组织学、四环素骨标记、显微放射摄影和扫描电子显微镜观察

SummaryThe effects of two steroid preparations (Hydrocortone and Celestona Bifas) on the acid and alkaline phosphatase levels in the synovial fluids were studied in patients with rheumatoid arthritis. One knee joint was treated with steroid and the effects on the enzyme levels were followed in both the treated and the contralateral untreated joint. Significant decrease of both acid and alkaline phosphatase was found in joints treated with Hydrocortone. No significant effect was observed for Celestona Bifas. The results suggest that the effects of Hydrocortone on acid and alkaline phosphatase were due to different mechanisms.

R. K. Lemperg

G. N. M. Beckman

L. E. A. Beckman

Effect of Intraarticular Corticosteroid Administration on Acid and Alkaline Phosphatase Activity in Synovial Fluid of Patients with Rheumatoid Arthritis

关节内皮质类固醇注射对类风湿关节炎患者滑液中酸性和碱性磷酸酶活性的影响

Veikko L. Laine

From the editor

来自编辑

SummaryThe radiographic appearance of the pubic symphysis was studied in 158 normal subjects of varying age and in 67 and 22 cases of RA and ankylosing spondylitis, respectively. The pubic symphysis undergoes significant anatomical changes during post-adolescent life. In old age changes typical of osteoarthritic deformation are seen. Small local erosions are significantly more frequent in RA patients than in the normal population. Changes in ankylosing spondylitis tend to be more extensive and easily visible than in RA. Tomographic studies suggest that minor changes typical of RA are often not revealed by ordinary radiography, owing to the peculiar anatomical features of the symphysis.

Radiographic Appearance of the Pubic Symphysis in Old Age and in Rheumatoid Arthritis

老年及类风湿性关节炎中耻骨联合的放射学表现

SummaryThe MBF in the tibial muscle of RA patients was studied by a Xe-133 clearance method. The MBF, both at rest and after muscular ischemia, was significantly reduced in RA. The decrease in MBF was not clearly dependent on swelling of the neighbouring joints in the extremity studied. The RA patients showed a greater increase in MBF after muscular ischemia than the controls.No correlation was observed between MBF at rest and the ESR, Waaler-Rose titer, duration of the disease and age. In fresh hemiplegic cases there was no clear difference in MBF between the involved and contralateral extremity.The following conclusions were drawn: 1. The reduced MBF in RA reflects the changes in the muscular microcirculation; 2. The central nervous system plays no major role in the development of the diminished MBF in RA.

Ahti Rekonen

Irma Elomaa

Muscle Blood Flow in Rheumatoid Arthritis

类风湿性关节炎中的肌肉血流

出版信息	出版商: Steinviks Bokforlag，出版周期: ，期刊类型: journal，开源期刊: 否
基本数据	创刊年份: 1955，原创研究文献占比: ，自引率:， Gold OA占比:

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Electrodiagnostic Investigation of the Neuromuscular Lesions in Rheumatoid Arthritis

Muramidase (Lysozyme) in Joint Fluid and Serum of Rheumatic Patients

A Microradiographic and Histological Study of the Manubrio-Sternal Joint in Rheumatoid Arthritis

Some Aspects of Epidemiology and Surveillance of Rheumatic Fever

Clearance of¹²⁵I-Labelled Urographin from Knee Joints in Rheumatoid Arthritis

Ankylosing Spondylitis: Report of one Case Studied with Histology, Tetracycline Bone Labelling, Microradiography and Scanning Electron Microscopy

Effect of Intraarticular Corticosteroid Administration on Acid and Alkaline Phosphatase Activity in Synovial Fluid of Patients with Rheumatoid Arthritis

From the editor

Radiographic Appearance of the Pubic Symphysis in Old Age and in Rheumatoid Arthritis

Muscle Blood Flow in Rheumatoid Arthritis

Acta rheumatologica Scandinavica

期刊引文格式

有 1 位以上作者的期刊

有 2 位作者的期刊

有 3 位作者的期刊

有 5 位以上作者的期刊

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Electrodiagnostic Investigation of the Neuromuscular Lesions in Rheumatoid Arthritis

Muramidase (Lysozyme) in Joint Fluid and Serum of Rheumatic Patients

A Microradiographic and Histological Study of the Manubrio-Sternal Joint in Rheumatoid Arthritis

Some Aspects of Epidemiology and Surveillance of Rheumatic Fever

Clearance of125I-Labelled Urographin from Knee Joints in Rheumatoid Arthritis

Ankylosing Spondylitis: Report of one Case Studied with Histology, Tetracycline Bone Labelling, Microradiography and Scanning Electron Microscopy

Effect of Intraarticular Corticosteroid Administration on Acid and Alkaline Phosphatase Activity in Synovial Fluid of Patients with Rheumatoid Arthritis

From the editor

Radiographic Appearance of the Pubic Symphysis in Old Age and in Rheumatoid Arthritis

Muscle Blood Flow in Rheumatoid Arthritis

Clearance of¹²⁵I-Labelled Urographin from Knee Joints in Rheumatoid Arthritis