Kemija u industriji/Journal of Chemists and Chemical Engineers

U radu je prikazan doprinos istraživanju glukozinolata u razdoblju 2005. – 2020. koji je ostvaren radom na Kemijsko-tehnološkom fakultetu, Sveučilišta u Splitu. Pregledom sveoubuhvatne dokumentacije utvrđeno je da znatnom broju predloženih struktura nedostaju važne strukturne informacije koje bi osigurala NMR i MS spektroskopija, pa je danas broj glukozinolata još uvijek varijabilan. U najnovijem istraživanju, u rodu Hesperis , identificiran je 4- O -D-apiozilglukomatronalin, čime ukupni broj glukozinolata danas broji između 89 i 136 struktura. U svrhu identificiranja izvora specifičnih glukozinolata koji bi mogli djelovati kao prekursori biološki aktivnih izotiocijanata, istraživan je sadržaj glukozinolata u biljkama. Istraživanja uključuju i razgradnju glukozinolata (enzimska, termička i kemijska) kao i biološku aktivnost (citotoksična, antimikrobna, protuupalna i dr.).

Ivica Blažević

Kemija u industriji

Doprinos istraživanju glukozinolata (2005. – 2020.)

葡萄糖硫苷研究贡献（2005-2020）

Ana Vučak

Glorija Golubić

Franko Burčul

Development and Validation of a GC-MS/MS Method for the Simultaneous Quantification of Selected Compounds in Essential Oils

开发和验证用于精油中选定化合物同时定量的GC-MS/MS方法

Nadežda Seratlić

Nevena Hromiš

Senka Popović

Danijela Šuput

Jovana Pantić

Ivana Čabarkapa

Degree of Chitosan Deacetylation: Potential of Experimental Equations Application

壳聚糖脱乙酰度：实验方程应用潜力

Modern chemotherapeutic agents offer versatile and potent applications for treatment of various forms of sarcomas.One such agent, doxorubicin, offers potent chemotherapeutic effects through its property of intercalation with DNA, resulting in rapid DNA degradation and cancer cell apoptosis.Despite its advanced properties, its application causes system-wide damage leading to cardiotoxicity and even lowering of cognitive scores, inhibition of self-regeneration, and nephropathy.To circumvent these adverse side-effects, localised drug delivery via a polymeric composite material may offer a solution.Chitosan, a biodegradable polymer, is a biocompatible polysaccharide capable of acting as an effective polymeric matrix for targeted drug delivery.In combination with bioactive glass, a composite polymeric scaffold could enhance the incorporation and release kinetics of doxorubicin from the polymer-based carrier while also promoting the formation of regenerative bone-like apatite.This work aimed to prepare chitosan/bioactive glass composite scaffolds as biodegradable carriers for doxorubicin in bone tumour treatment.The composite scaffolds were prepared with varying weight fractions of bioactive glass (0-30 %) within the chitosan matrix using thermally induced phase separation followed by solvent sublimation.The resulting scaffolds were characterised using X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy assisted with energy-dispersive X-ray spectroscopy.The drug was loaded into the scaffolds by immersing them in doxorubicin solutions of different concentrations (25 and 50 ppm) for 5 h.The release of doxorubicin was then studied in a phosphate buffer solution (pH 7.4) over a 24-h period using fluorescence spectrometry after scaffold immersion.

Luka Dornjak

Anamarija Rogina

Chitosan/Bioactive Glass Scaffolds as Potential Drug Carriers

壳聚糖/生物活性玻璃支架作为潜在药物载体

Lamija Ahmetović

Veronika Furlan

Urban Bren

Computational Modelling of Anti-Carcinogenic Effects of Naringenin

柚皮素抗癌作用的计算建模

Goran Lukač

Ivan Bilmez

Igor Dejanović

Application of the Christiansen Dividing-wall Column Configuration for Multicomponent System Separation

多组分系统分离的Christiansen隔墙柱配置应用

短名	Kem. Ind.
Journal Impact	0.74
国际分区	CHEMISTRY, MULTIDISCIPLINARY(Q4)

涉及主题	哲学物理化学语言学克罗地亚语生物有机化学材料科学艺术人文学科
出版信息	出版商: Assoc. of Chemists and Chemical Engineers of Croatia，出版周期: ，期刊类型: journal，开源期刊: 是
基本数据	创刊年份: 2001，原创研究文献占比: 85.51%，自引率:16.70%， Gold OA占比: 80.29%
平均审稿周期	网友分享经验：24 Weeks

Kemija u industriji/Journal of Chemists and Chemical Engineers

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Doprinos istraživanju glukozinolata (2005. – 2020.)

Development and Validation of a GC-MS/MS Method for the Simultaneous Quantification of Selected Compounds in Essential Oils

Degree of Chitosan Deacetylation: Potential of Experimental Equations Application

Chitosan/Bioactive Glass Scaffolds as Potential Drug Carriers

Computational Modelling of Anti-Carcinogenic Effects of Naringenin

Development and Validation of a GC-MS/MS Method for the Simultaneous Quantification of Selected Compounds in Essential Oils

Degree of Chitosan Deacetylation: Potential of Experimental Equations Application

Chitosan/Bioactive Glass Scaffolds as Potential Drug Carriers

Computational Modelling of Anti-Carcinogenic Effects of Naringenin

Application of the Christiansen Dividing-wall Column Configuration for Multicomponent System Separation