Bulletin de la Societe Belge d'Ophtalmologie

The visual cortex may be involved in adverse drug reactions, leading to three different clinical presentations: cortical blindness, visual hallucinations and visual aura without headache. The drugs with potential visual cortex toxicity are described.

Monique Cordonnier

Bulletin de la Société belge d'ophtalmologie

Le cortex visuel est-il concerné?

视觉皮层是否受影响？

The antimalarial agents Chloroquine and Hydroxychloroquine are used for the treatment of inflammatory disorders such as rheumatoid arthritis and lupus erythematosus. The first published reports of retinal toxicity appeared in 1959. Despite a low incidence for low doses and a short period of time, a regular ophthalmological screening is recommended to detect this maculopathy early. High risk criteria are: > 3 mg/kg/d of Chloroquine or > 6.5 mg/kg/d of Hydroxychloroquine, duration of treatment > 5 years, obesity, renal or hepatic disease, old age or pre-existing macular disease. Annual screening, and in some cases every 6 months, is recommended for high risk patients. Low risk patients will have an ophthalmologic examination every 18 months. The baseline examination includes visual acuity, Amsler grid, biomicroscopy, automated perimetry (central 10 degrees), color vision testing and fundus. Fluoroangiography and (multifocal) electroretinography should be considered if baseline screening is doubtfull or if toxicity is suspected. If relative paracentral bilateral scotomas or subtle alterations of retinal pigmentary epithelium are documented, the drug should be stopped. The collaboration with the internist and good information to the patient are necessary.

Anne Vanheesbeke

Rétine et epithélium pigmentaire--le point sur les antipaludéens de synthése.

视网膜与色素上皮——关于合成抗疟药的综述

Central serous chorioretinopathy (CSC) is a relatively frequent ocular disorder. Its pathophysiology remains however unclear. This disease typically affects young men with type A behaviour within a context of stressful events. Recently, endogenous or exogenous hypercortisolism has been associated with development, prolongation and exacerbation of CSC. Exogenous hypercortisolism has been induced by any route: intravenous, cutaneous, or nasal spray. Some clinical features such as bilaterality of lesions, an atypical form of the presentation can evoke this association. Although a few years ago glucocorticoids were still used as treatment of CSC, experimental and clinical observations suggest that they are contra-indicated in the context of CSC.

Florence Rasquin

Corticoïdes et choriorétinite séreuse centrale.

皮质类固醇与中心性浆液性脉络膜视网膜病变。

Les antiviraux, antimycotiques et antibiotiques sont tres efficaces dans la prise en charge des infections intra-oculaires lorsqu'ils sont injectes en intravitreens, alors qu'ils sont peu utiles, a quelques exceptions pres, apres administration bucale, intraveineuse ou peribulbaire. Cependant, ils ont une potentialite toxique sur la retine plus importante apres injection intra-oculaire que par les autres voies. A cause de leur toxicite particuliere, les aminoglycosides ont ete remplaces par le Ceftazidime et la Vancomycine, dans la prise en charge des endophtalmites bacteriennes. Leur efficacite n'est pas formellement demontree dans la prophylaxie des infections intra-oculaires, tandis que leur potentialite toxique demeure preoccupante.

Jacques Libert

La toxicité des injections intravitréennes d'antibiotiques et antiviraux

玻璃体内注射抗生素和抗病毒药物的毒性

KERATOUVEITIS AND LENS OPACITY CAUSED BY BUTTERFLY HAIR Butterfly hair is known to cause eye injury. In Africa, incriminated butterflies are Hylesia (spp). We report a case of a sub-epithelial keratitis associated with anterior uveitis following a trauma by a butterfly that was complicated by late lens opacity due to butterfly hair. Ocular lesions caused by butterfly hair are rare, but require an urgent management to prevent late and severe complications due to intraocular migration of the hairs. MOTS-CLES Papillon, keratite, uveite, cataracte

C Domngang Noche

B Kengmogne

A L Bella

Kerato-uveite et opacite du cristallin secondaire a un traumatisme oculaire par papillon: a propos d'un cas.

角膜葡萄膜炎及继发性外伤性白内障：一例蝴蝶致眼外伤报告。

Lies De Groef

Eline Dekeyster

Djoere Gaublomme

Lieve Moons

Glaucoma from eye to brain: are MMP-2 and MMP-14 involved?

青光眼：从眼到脑，MMP-2和MMP-14是否参与其中？

角膜葡萄膜炎及继发性外伤性白内障：一例蝴蝶致眼外伤病例报告。

Tolerance of porous polyethylene orbital implants in children Introduction: The purpose of our study is to deter- mine the incidence of orbital complications that oc- curred after insertion of orbital porous polyethylene implant in children under the age of 15 years.

出版信息	出版商: Societe Belge d'Ophtalmologie，出版周期: ，期刊类型: journal，开源期刊: 否
基本数据	创刊年份: 1951，原创研究文献占比: ，自引率:， Gold OA占比:

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Le cortex visuel est-il concerné?

Rétine et epithélium pigmentaire--le point sur les antipaludéens de synthése.

Corticoïdes et choriorétinite séreuse centrale.

La toxicité des injections intravitréennes d'antibiotiques et antiviraux

Kerato-uveite et opacite du cristallin secondaire a un traumatisme oculaire par papillon: a propos d'un cas.

Glaucoma from eye to brain: are MMP-2 and MMP-14 involved?

Kerato-uveite et opacite du cristallin secondaire a un traumatisme oculaire par papillon: a propos d'un cas.

TOLÉRANCE DES IMPLANTS ORBITAIRES EN POLYÉTHYLÈNE POREUX CHEZ L'ENFANT