Acta Pathologica Microbiologica et Immunologica Scandinavica - Section B Microbiology

A case of cutaneous alternariosis is reported in the wife of a 73‐year‐old farmer. The diagnosis was verified culturally and histologically. The skin lesions were localized to legs, arms and face and were characterized by alternating spontaneous healing and formation of new lesions possibly due to autoinoculation from the lesions or re‐exposure to the environment. The patient had a decreased resistance to infections owing to cancer – for which she had received X‐ray treatment, chemotherapy and cortisone. This is the first reported Danish case.

J. Stenderup

MARIANNE Bruhn

C. Gadeberg

A. Stenderup

Acta Pathologica Microbiologica Scandinavica Series B Microbiology

CUTANEOUS ALTERNARIOSIS

皮肤交替性坏死

Fifty-two strains found to belong to Flavobacterium meningosepticum on the basis of DNA-DNA hybridization analyses were characterized and found to be phenotypically homogeneous. All strains were oxidase, catalase, indole, gelatinase and beta-galactosidase positive, and produced acid from glucose, mannose, fructose, maltose and mannitol; nitrate was not reduced. F. meningosepticum could be differentiated from Flavobacterium group IIb by its ability to produce beta-galactosidase, and by the latter taxon's ability to produce a bright yellow pigment in contrast to the weak or non-existing pigmentation of F. meningosepticum. Phenotypic characteristics that could differentiate between the two main DNA relatedness groups of F. meningosepticum were not discovered, wherefore a subdivision of the present species into two species cannot be recommended. Strains from the DNA relatedness groups comprising 19 of 20 CSF isolates were found to be able to grow at 40 degrees C and to produce a weak yellow pigment; in contrast, strains from the three other DNA relatedness groups were unable to grow at 40 degrees C and produced no pigment.

BRITA Bruun

JAN Ursing

PHENOTYPIC CHARACTERIZATION OF FLAVOBACTERIUM MENINGOSEPTICUM STRAINS IDENTIFIED BY DNA‐DNA HYBRIDIZATION

通过DNA-DNA杂交鉴定的黄杆菌属脑膜炎败血症菌株的表型特征

The immunological relation between serum antibodies to pneumolysin and to streptolysin O was studied in patients with pneumococcal pneumonia (n=40), patients with infections due to β‐haemolytic streptococci (n=35), healthy human controls (n=60) and in rabbits immunized with pneumolysin. There was no correlation between anti‐pneumolysin and anti‐streptolysin O titers (r=‐0.279). The distribution of anti‐pneumolysin titers in patients with high anti‐streptolysin O titers did not differ from healthy controls. However, there was a tendency to increased or rising anti‐streptolysin O titers in patients with pneumococcal infection. Antibodies obtained during pneumococcal infection might thus give false‐positive reactions in the streptolysin O neutralization test. Serum antibodies to streptolysin O do not cross‐react with pneumolysin in an ELISA. The pneumolysin ELISA for detection of pneumococcal disease will therefore not be disturbed by false‐positive reactions due to antibodies directed against β‐haemolytic streptococci.

KRZYSZTOF Kanclerski

MARTA GranstrÖM

ROLAND MÖLlby

IMMUNOLOGICAL RELATION BETWEEN SERUM ANTIBODIES AGAINST PNEUMOLYSIN AND AGAINST STREPTOLYSIN O

血清抗肺炎溶血素与抗链溶血素O的免疫学关系

Fifty Salmonella dublin strains isolated from cattle and human diarrhoeal cases were assayed for toxin production, haemagglutination, cell‐surface hydrophobicity and fibronectin‐binding properties. Most strains (65% of tested) produced cytotonic toxins and cytotoxic factors when tested on Chinese hamster ovary (CHO) cells and rabbit skin test. However, only three strains produced a skin‐permeability factor as determined in pig skin intra‐dermal tests. None of the strains were positive in pig intestinal loop tests. Six of the 32 strains tested for 125 I‐fibronectin and its 125 I‐29 kDa N‐terminal domain binding showed 10–17% and 6–10% binding, respectively. Most of the strains expressed mannose‐sensitive haemagglutination (MSHA) (76%) and high cell‐surface hydrophobicity (74%) when grown at 37 °C. At 20 °C the expression of MSHA and especially the expression of high cell‐surface hydrophobicity were reduced. Twelve strains grown at 37 °C did not haemagglutinate erythrocytes from five animal species used in this study, while six of these strains expressed high cell‐surface hydrophobicity. Salmonella dublin strains isolated in Denmark appeared to express a higher frequency of fimbriae type 1 (MSHA) and a lower frequency of high cell‐surface hydrophobicity than the strains from external sources.

KARINA Kristiansen

SURAJ B. Baloda

JENS L. Larsen

TORKEL WadstrÖM

TOXINS, PUTATIVE CELL ADHESINS AND FIBRONECTIN BINDING PROPERTIES OF SALMONELLA DUBLIN

都柏林沙门氏菌的毒力因子、假定细胞粘附素及纤连蛋白结合特性

During a two‐year period, Streptococcus suis serotypes 1–8 were isolated from 108 pigs examined at the laboratory. S. suis serotypes 2 and 7 represented 75% of the isolates. S. suis serotype 7 was isolated more frequently than reported from other countries, and mostly from piglets less than 3 weeks of age. Experimental inoculation of 7‐day‐old piglets with S. suis serotype 7 provoked severe illness within a week in 6 out of 7 animals. By bacteriological and pathological examination it was found that S. suis serotype 7 was pathogenic to piglets, giving rise to septicemia with predilection for joints, serous membranes and meninges.

ANETTE G. Boetner

MARIANNE Binder

VIVI Bille‐Hansen

STREPTOCOCCUS SUIS INFECTIONS IN DANISH PIGS AND EXPERIMENTAL INFECTION WITH STREPTOCOCCUS SUIS SEROTYPE 7

丹麦猪链球菌感染及链球菌7型实验感染

Thirteen serovars of Ureaplasma urealyticum were analyzed for the ability to cleave human IgA. Strains of all of the serovars tested cleaved IgA 1 in the hinge region of the alpha-chain, resulting in intact Fc and monomeric Fab fragments. IgA 1 protease activity was also observed in concentrated cell-free extracts of spent cultivation medium, indicating that the IgA 1 protease was excreted into the medium during growth of the micro-organisms. Five clinical isolates of U. urealyticum obtained from urine, cervix, vagina, amniotic fluid, and synovial fluid were positive for IgA 1 protease activity. No proteolytic activity was observed against human IgA 2, IgG, or IgM. Strains of Mycoplasma fermentans, M. salivarium and seven serovars of M. hominis were negative for IgA 1 protease activity.

出版信息	出版商: Wiley-Blackwell Publishing Ltd，出版周期: ，期刊类型: journal，开源期刊: 否
基本数据	创刊年份: 1983，原创研究文献占比: ，自引率:， Gold OA占比:

Acta Pathologica Microbiologica et Immunologica Scandinavica - Section B Microbiology

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CUTANEOUS ALTERNARIOSIS

PHENOTYPIC CHARACTERIZATION OF FLAVOBACTERIUM MENINGOSEPTICUM STRAINS IDENTIFIED BY DNA‐DNA HYBRIDIZATION

IMMUNOLOGICAL RELATION BETWEEN SERUM ANTIBODIES AGAINST PNEUMOLYSIN AND AGAINST STREPTOLYSIN O

TOXINS, PUTATIVE CELL ADHESINS AND FIBRONECTIN BINDING PROPERTIES OF SALMONELLA DUBLIN

STREPTOCOCCUS SUIS INFECTIONS IN DANISH PIGS AND EXPERIMENTAL INFECTION WITH STREPTOCOCCUS SUIS SEROTYPE 7

IMMUNOGLOBULIN A1 PROTEASE ACTIVITY IN STRAINS OF UREAPLASMA UREALYTICUM

CUTANEOUS ALTERNARIOSIS

PHENOTYPIC CHARACTERIZATION OF FLAVOBACTERIUM MENINGOSEPTICUM STRAINS IDENTIFIED BY DNA‐DNA HYBRIDIZATION

IMMUNOLOGICAL RELATION BETWEEN SERUM ANTIBODIES AGAINST PNEUMOLYSIN AND AGAINST STREPTOLYSIN O

TOXINS, PUTATIVE CELL ADHESINS AND FIBRONECTIN BINDING PROPERTIES OF SALMONELLA DUBLIN