《生物科学杂志》是班加罗尔印度科学院出版的季刊。它涵盖生物学的所有领域，是其范围内的国内一流期刊。它在当前目录和其他标准生物和医学数据库中被索引。 《生物科学杂志》始于 1934 年，当时是《印度科学院院刊》（B 部分）。这种情况一直持续到 1978 年，当时它被分为三个部分：PROCEEDINGS-ANIMAL SCIENCES、PROCEEDINGS-PLANT SCIENCES 和 PROCEEDINGS-EXPERIMENTAL BIOLOGY。 1979年PROCEEDINGS-EXPERIMENTAL BIOLOGY更名为JOURNAL OF BIOSCIENCES； 1991 年，PROCEEDINGS-ANIMAL SCIENCES 和 PROCEEDINGS-PLANT SCIENCES 与其合并。

The Journal of Biosciences is a quarterly publication by the Indian Academy of Sciences in Bangalore, covering all areas of biology and recognized as a leading national journal in its field. It is indexed in current directories and other standard biological and medical databases. The journal was established in 1934 as part of the Proceedings of the Indian Academy of Sciences (Section B). In 1978, it was divided into three sections: Proceedings-Animal Sciences, Proceedings-Plant Sciences, and Proceedings-Experimental Biology. In 1979, the Proceedings-Experimental Biology was renamed the Journal of Biosciences; in 1991, the Proceedings-Animal Sciences and Proceedings-Plant Sciences were merged into it.

《生物科学杂志》是由班加罗尔印度科学院出版的季刊，涵盖生物学的所有领域，是该领域内的国内一流期刊。该期刊在当前目录和其他标准生物与医学数据库中被广泛索引。《生物科学杂志》创刊于1934年，最初是《印度科学院院刊》（B部分）。1978年，该期刊分为三个部分：动物科学、植物科学和实验生物学。1979年，实验生物学部分更名为Journal of Biosciences；1991年，动物科学和植物科学部分与其合并。

Journal of Biosciences

In order to improve crop plants in terms of their yield, drought resistance, pest resistance, nutritional value, etc., modern agriculture has relied upon plant genetic engineering. Since the advent of recombinant DNA technology, several tools have been used for genetic transformations in plants such as Agrobacterium tumefaciens, virus-mediated gene transfer, direct gene transfer systems such as electroporation, particle gun, microinjection and chemical methods. All these traditional methods lack specificity and the transgenes are integrated at random sites in the plant DNA. Recently novel techniques for gene targeting have evolved such as engineered nucleases such as Zinc Finger Nucleases, Transcription Activator like effector nucleases, Clustered regular interspaced short palindromic repeats. Other advances include improvement in tools for delivery of gene editing components which include carrier proteins, and carbon nanotubes. The present review focuses on the latest techniques for target specific gene delivery in plants, their expression and future directions in plant biotechnology.

Debdyuti Nandy

Amrita Maity

Arup Kumar Mitra

Journal of biosciences

J Biosci

Target-specific gene delivery in plant systems and their expression: Insights into recent developments.

Nidhi Singh

Ashis Kumar Nandi

AtOZF1 positively regulates JA signaling and SA-JA cross-talk in Arabidopsis thaliana

AtOZF1正向调控拟南芥中的茉莉酸信号和茉莉酸-水杨酸交叉对话

CpG islands are generally known as the epigenetic regulatory regions in accordance with histone modifications, methylation, and promoter activity. There is a significant need for the exact mapping of DNA methylation in CpG islands to understand the diverse biological functions. However, the precise identification of CpG islands from the whole genome through experimental and computational approaches is still challenging. Numerous computational methods are being developed to detect the CpG-enriched regions, effectively, to reduce the time and cost of the experiments. Here, we review some of the latest computational CpG detection methods that utilize clustering, patterns and physical-distance like parameters for CpG island detection. The comparative analyses of the methods relying on different principles and parameters allow prioritizing the algorithms for specific CpG associated datasets to achieve higher accuracy and sensitivity. A number of computational tools based on the window, Hidden Markov Model, density and distance-/length-based algorithms are being applied on human or mammalian genomes for accurate CpG detection. Comparative analyses of CpG island detection algorithms facilitate to prefer the method according to the target genome and required parameters to attain higher accuracy, specificity, and performance. There is still a need for efficient computational CpG detection methods with lower false-positive results. This review provides a better understanding about the principles of tools that will assist to prioritize and develop the algorithms for accurate CpG islands detection.

Rana Adnan Tahir

D A Zheng

Amina Nazir

Hong Qing

A review of computational algorithms for CpG islands detection.

CpG岛检测计算算法综述。

Camptothecin (CPT), a monoterpene indole alkaloid, is a potent inhibitor of DNA topoisomerase I and has applications in treating ovarian, small lung and refractory ovarian cancers. Stem wood tissue of Nothapodytes nimmoniana (Graham) Mabb. (family Icacinaceae) is one of the richest sources of CPT. Since there is no genomic or transcriptome data available for the species, the present work sequenced and analysed transcriptome of stem wood tissue on an Illumina platform. From a total of 77,55,978 reads, 9,187 transcripts were assembled with an average length of 255 bp. Functional annotation and categorization of these assembled transcripts unraveled the transcriptome architecture and also a total of 13 genes associated with CPT biosynthetic pathway were identified in the stem wood tissue. Four genes of the pathway were cloned to full length by RACE to validate the transcriptome data. Expression analysis of 13 genes associated with CPT biosynthetic pathway in 11 different tissues vis-a-vis CPT content analysis suggested an important role of NnPG10H, NnPSLS and NnPSTR genes in the biosynthesis of CPT. These results indicated that CPT might be synthesized in the leaves and then perhaps exported to stem wood tissue for storage.

B L Manjunatha

H R Singh

G Ravikanth

Karaba N Nataraja

Ravi Shankar

Sanjay Kumar

R Uma Shaanker

Transcriptome analysis of stem wood of Nothapodytes nimmoniana (Graham) Mabb. identifies genes associated with biosynthesis of camptothecin, an anti-carcinogenic molecule.

Nothapodytes nimmoniana (Graham) Mabb. 茎木材转录组分析鉴定了与喜树碱生物合成相关的基因，喜树碱是一种抗癌分子。

Plants are invaded by an array of pathogens of which only a few succeed in causing disease. The attack by others is countered by a sophisticated immune system possessed by the plants. The plant immune system is broadly divided into two, viz. microbial-associated molecular-patterns-triggered immunity (MTI) and effector-triggered immunity (ETI). MTI confers basal resistance, while ETI confers durable resistance, often resulting in hypersensitive response. Plants also possess systemic acquired resistance (SAR), which provides long-term defense against a broad-spectrum of pathogens. Salicylic-acid-mediated systemic acquired immunity provokes the defense response throughout the plant system during pathogen infection at a particular site. Trans-generational immune priming allows the plant to heritably shield their progeny towards pathogens previously encountered. Plants circumvent the viral infection through RNA interference phenomena by utilizing small RNAs. This review summarizes the molecular mechanisms of plant immune system, and the latest breakthroughs reported in plant defense. We discuss the plant–pathogen interactions and integrated defense responses in the context of presenting an integral understanding in plant molecular immunity.

Mehanathan Muthamilarasan

Manoj Prasad

Plant innate immunity: an updated insight into defense mechanism.

植物先天免疫：防御机制的最新见解。

Anica Dadwal

Shilpa Sharma

Shailendra Asthana

Supratik Das

Trypanosomatid DRBD9s are likely to be eIF4B orthologues

锥虫科的DRBD9可能与eIF4B同源

Rasitha Santhosh Kanakalatha

Anoopkumar Thekkuveettil

Memory defects in post-dauer Caenorhabditis elegans are a result of altered insulin signalling

post-dauer秀丽隐杆线虫记忆缺陷是胰岛素信号改变的结果

Sonu Pahal

Vishvender Pahal

Amit Chaudhary

From data to discovery: Neuroinformatics in understanding Alzheimer's disease

从数据到发现：神经信息学在理解阿尔茨海默病中的作用

Mrityunjay C Chinkate

Anshul Tiwari

Devendra Kumar Patel

Aruna Satish

Toxicity assessment of wastewater treatment plant sludge using Caenorhabditis elegans

利用秀丽隐杆线虫评估污水处理厂污泥的毒性

Renee M. Borges

Convergent evolution: What do cats, catnip, aphids, and mosquitoes have in common?

趋同进化：猫、猫薄荷、蚜虫和蚊子有什么共同点？

Abbreviation	J Biosci
Journal Impact	1.97
Quartiles(Global)	BIOLOGY(Q2)

ISSN	0250-5991, 0973-7138
h-index	85

Publication Information	Publisher: Springer，Publishing cycle: Quarterly，Journal Type: journal，Open Access Journals: No
Basic data	Year of publication: 1979，Proportion of original research papers: 66.22%，Self Citation Rate:0.00%， Gold OA Rate: 2.46%
Average review cycle	网友分享经验：较慢,6-12周
Average recruitment ratio	网友分享经验：较易

Journal of Biosciences

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