CYP2E1 mediated deoxynivalenol-induced hepatocyte toxicity by regulating ferroptosis

2024-11-1

A Novel “Cells-on-Particles” Cytotoxicity Testing Platform In vitro: Design, Characterization, and Validation against Engineered Nanoparticle Aerosol

2024-11-1

A review on e-waste contamination, toxicity, and sustainable clean-up approaches for its management

2024-11-1

Assessment of Cytotoxic and Genotoxic Effects of Glyphosate-Based Herbicide on Glioblastoma Cell Lines: Role of p53 in Cellular Response and Network Analysis

2024-11-1

Editorial Board

2024-11-1

Exosomes-mediated retinoic acid disruption: A link between gut microbiota depletion and impaired spermatogenesis

2024-11-1

Ferroptosis contributes to lead-induced cochlear spiral ganglion neurons injury

2024-9-13

HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration

2024-9-1

Developmental neurotoxicity evaluation of acrylamide based on in vitro to in vivo extrapolation by pregnancy PBTK modelling

2024-9-1

Long-term exposure to polystyrene microplastics reduces macrophages and affects the microbiota–gut–brain axis in mice

2024-9-1

Evidence for enduring cardiac and multiorgan toxicity after repeated exposure to the synthetic cannabinoid JWH-018 in male rats

2024-9-1

Pleiotrophin modulates acute and long-term LPS-induced neuroinflammatory responses and hippocampal neurogenesis

2024-9-1

4-Phenylbutyric acid suppresses psoralen-induced hepatotoxicity by inhibiting ERS and reestablishing mitochondrial fusion-fission balance in mice

2024-9-1

Exposure to environmental doses of DEHP causes phenotypes of polycystic ovary syndrome

2024-9-1

How does organophosphorus chemical warfare agent exposure affect respiratory physiology in mice?

2024-9-1

Targeting SIRT1/AMPK/Nrf2/NF-кB by sitagliptin protects against oxidative stress-mediated ER stress and inflammation during ANIT-induced cholestatic liver injury

2024-9-1

Heavy metals altered the xenobiotic metabolism of rats by targeting the GST enzyme: an invitro and insilico study

2024-9-1

Transcriptomics and metabolomics analyses of graphene oxide toxicity on porcine alveolar macrophages

2024-9-1

Insights Gained Into the Injury Mechanism of Drug and Herb Induced Liver Injury in the Hepatic Microenvironment

2024-9-1

Drug-induced enzyme activity inhibition and CYP3A4 genetic polymorphism significantly shape the metabolic characteristics of furmonertinib

2024-9-1

The zebrafish embryo as a model for chemically-induced steatosis: a case study with three pesticides

2024-8-14

Prenatal exposure to dibutyl phthalate contributes to erectile dysfunction in offspring male rats by activating the RhoA/ROCK signalling pathway

2024-8-14

Editorial Board

2024-8-13

Benzopyrene represses mitochondrial fission factors and PINK1/Parkin-mediated mitophagy in primary astrocytes

2024-8-13

Investigating the cardiotoxicity of N-n-butyl haloperidol iodide: Inhibition mechanisms on hERG channels

2024-8-12

Effects of isochlorogenic acid A on mitochondrial dynamics imbalance and RLR damage in PAM cells induced by combined mycotoxins

2024-8-11

Urinary GM2AP coincides with renal cortical damage and grades cisplatin nephrotoxicity severity in rats

2024-8-11

Machine learning-driven QSAR models for predicting the cytotoxicity of five common microplastics

2024-8-11

Alendronate sodium induces G1 phase arrest and apoptosis in human umbilical vein endothelial cells by inhibiting ROS-mediated ERK1/2 signaling

2024-8-11

Hexavalent chromium reduces testosterone levels by impairing lipophagy and disrupting lipid metabolism homeostasis: Based on a metabolomic analysis

2024-8-8

Proteasome inhibition induces apoptosis through simultaneous inactivation of MCL-1/BCL-XL by NOXA independent of CHOP and JNK pathways

2024-8-6

Long-term toxicity evaluation of aristolochic acid-IIIa in mice

2024-8-1

MLKL deficiency alleviates acute alcoholic liver injury via inhibition of NLRP3 inflammasome

2024-8-1

Analysis of environmental pollutant Bisphenol F elicited prostate injury targets and underlying mechanisms through network toxicology, molecular docking, and multi-level bioinformatics data integration

2024-8-1

Embryonic Ethanol Exposure Induces Oxidative Stress and Inflammation in Zebrafish Model: A Dose-Dependent Study

2024-8-1

Evaluating combined effects of chronic, low-dose exposures of cadmium (CLEC) and hyperglycemia on insulin signaling dysfunction in a hepatocellular model

2024-8-1

An In-depth Examination of Per- and Polyfluoroalkyl (PFAS) Effects on Transporters, with Emphasis on the ABC Superfamily: A Critical Review

2024-8-1

Mutual regulation between histone methyltransferase Suv39h1 and the Wnt/β-catenin signaling pathway promoted cell proliferation and inhibited apoptosis in bone marrow mesenchymal stem cells exposed to hydroquinone

2024-8-1

The role of β2-AR/PI3K/AKT pathway in the proliferation, migration and invasion of THLE-2 cells induced by nicotine

2024-8-1

Using Microfluidic and Conventional Platforms to Evaluate the Effects of Lanthanides on Spheroid Formation

2024-8-1

Exploring the Protective Potential of Nrf2 Overexpressed Neural Extracellular Vesicles Against Cisplatin-induced Neurotoxicity via NRF2/ARE Pathway

2024-8-1

There is no need for overnight fasting of rats in regulatory toxicology studies

2024-8-1

Involvement of multiple epigenetic mechanisms by altered DNA methylation from the early stage of renal carcinogenesis before proliferative lesion formation upon repeated administration of ochratoxin A

2024-8-1

Fumonisin Distorts the Cellular Membrane Lipid Profile: A Mechanistic Insight

2024-8-1

Inhibitory Effects of Parabens on Human and Rat 17β-Hydroxysteroid Dehydrogenase 1: Mechanisms of Action and Impact on Hormone Synthesis

2024-8-1

Evaluating the embryotoxicity of benzophenone-based photoinitiators in stem cells and zebrafish embryos

2024-8-1

Nanoplastics trigger the aging and inflammation of porcine kidney cells

2024-8-1

Targeting Nrf2/HO-1 and NF-κB/TNF-α signaling pathways with empagliflozin protects against atrial fibrillation-induced acute kidney injury in rats

2024-8-1

Size-dependent Deleterious Effects of Nano- and Microplastics on Sperm Motility

2024-8-1

Toxicity mechanism of acrolein on energy metabolism disorder and apoptosis in human ovarian granulosa cells

2024-8-1