A simple air–liquid interface exposure system for exposing cultured human 3D epidermis and cornea to PM2.5 collected through cyclonic separation

2024-1-1

<i>Drosophila melanogaster</i> as potential alternative animal model for evaluating acute inhalation toxicity

2024-1-1

Analysis of cardiohemodynamic and electrophysiological effects of morphine along with its toxicokinetic profile using the halothane-anesthetized dogs

2024-1-1

Breast milk-mediated exposure to dioxins and antigen in infancy enhances antigen-specific antibody production capacity in adulthood in mice

2024-1-1

Lung carcinogenicity by whole body inhalation exposure to Anatase-type Nano-titanium Dioxide in rats

2024-1-1

Valproic acid elevates HIF-1α-mediated <i>CGB</i> expression and suppresses glucose uptake in BeWo cells

2024-1-1

Novel predictive approaches for drug-induced convulsions in non-human primates using machine learning and heart rate variability analysis

2024-1-1

Involvement of <i>microRNA-4680-3p</i> against phenytoin-induced cell proliferation inhibition in human palate cells

2024-1-1

Octanol/water partition coefficients estimated using retention times in reverse-phase liquid chromatography and calculated <i>in silico</i> as one of the determinant factors for pharmacokinetic parameter estimations of general chemical substances

2024-1-1

Comparison of the fecal bacterial microbiota in mice, rats, and pigs after oral administration of alpha-glycosyl isoquercitrin

2024-1-1

Effective <i>in vitro</i> evaluation of the risk of histamine release related to valemetostat tosylate using MRGPRX2-expressing cells

2024-1-1

Histological differences between the central and peripheral areas of the testes of busulfan-administered mice

2024-1-1

Protection of cultured vascular endothelial cells against cadmium cytotoxicity by simultaneous treatment or pretreatment with manganese

2024-1-1

Methylmercury-induced brain neuronal death in CHOP-knockout mice

2024-1-1

Investigation of normalization procedures for transcriptome profiles of compounds oriented toward practical study design

2024-1-1

Mechanism of luteolin induces ferroptosis in nasopharyngeal carcinoma cells

2024-1-1

Comparative sensitivity of laboratory animals used for preclinical convulsion risk assessment to drug-induced convulsion

2024-1-1

A single dose of clothianidin exposure induces varying sex-specific behavioral changes in adulthood depending on the developmental stage of its administration

2024-1-1

MiR-98-3p alleviates lipopolysaccharide-induced pulmonary microvascular endothelial barrier dysfunction by targeting DKK3 in sepsis-induced acute lung injury

2024-1-1

Industrially produced <i>trans</i>-fatty acids are potent promoters of DNA damage-induced apoptosis

2024-1-1

Transcriptome analysis of cultured human vascular endothelial cells after γ-ray irradiation and correlation analysis with ATP, ADP, and adenosine as secondary soluble factors

2024-1-1

Dihydropyrazine induces endoplasmic reticulum stress and inhibits autophagy in HepG2 human hepatoma cells

2024-1-1

Integrating mathematical approaches (IMAS): Novel methodology for predicting dermal absorption rates of chemicals under finite dose conditions

2024-1-1

Comparative study of susceptibility to methylmercury cytotoxicity in cell types composing rat peripheral nerves: a higher susceptibility of dorsal root ganglion neurons

2024-1-1

Transcriptome analysis in various cell lines exposed to nitric oxide

2024-1-1

Identification of post-mortem product of zolpidem degradation by hemoglobin via the Fenton reaction

2024-1-1

Carcinogenicity of butyraldehyde in rats by a two-year inhalation study

2024-1-1

Possible nonimmunological toxicological mechanisms of vesnarinone-associated agranulocytosis in HL-60 cells: role of reduced glutathione as cytotoxic defense

2024-1-1

Validation of a new protocol for a zebrafish MEFL (malformation or embryo-fetal lethality) test method that conforms to the ICH S5 (R3) guideline

2024-1-1

DTox: A deep neural network-based <i>in visio</i> lens for large scale toxicogenomics data

2024-1-1

Developing a GNN-based AI model to predict mitochondrial toxicity using the bagging method

2024-1-1

Discovery and development of COVID-19 vaccines and therapeutics: nonclinical perspectives

2024-1-1

Paternal methamphetamine exposure differentially affects first and second generations in mice

2024-1-1

Effects of food restriction on toxicological parameters in juvenile rats

2024-1-1

Reversible and monitorable nephrotoxicity in rats by the novel potent transcriptional enhanced associate domain (TEAD) inhibitor, K-975

2024-1-1

Retraction: <i>In utero</i>-exposed di(<i>n</i>-butyl) phthalate induce dose dependent, age-related changes of morphology and testosterone-biosynthesis enzymes/associated proteins of Leydig cell mitochondria in rats

2023-1-1

Small noncoding RNA dysregulation is implicated in manganism in a rat model of methylcyclopentadienyl manganese tricarbonyl-induced unrepaired striatum damage

2023-1-1

Tributyltin activates the Keap1–Nrf2 pathway via a macroautophagy-independent reduction in Keap1

2023-1-1

Effects of early-life tosufloxacin tosilate hydrate administration on growth rate, neurobehavior, and gut microbiota at adulthood in male mice

2023-1-1

Construction of extended and functional bile canaliculi using long-term sandwich-cultured cryopreserved human hepatocytes and the application of hepatocytes for predicting the biliary excretion of pharmaceutical and food-related compounds

2023-1-1

Rapid derivatization of phosphorus-containing amino acid herbicides in plasma and urine using microwave heating

2023-1-1

Oxidative stress and cellular toxicity induced by dihydropyrazine: a comparative study with other Maillard reaction products

2023-1-1

Simulation-based risk assessment for the leakage of toxic substances in a chemical plant and the effects on the human body: ethanol as a working model

2023-1-1

Development of a GCN-based model to predict <i>in vitro</i> phototoxicity from the chemical structure and HOMO-LUMO gap

2023-1-1

Establishment of an <i>in vitro</i> cholestasis risk assessment system using two-dimensional cultured HepaRG cells and 12 bile acids

2023-1-1

Preclinical <i>in vitro</i> evaluation of immune suppression induced by GYM329, Fc-engineered sweeping antibody

2023-1-1

Effects of inhalation of multi-walled carbon nanotube (MWCNT) on respiratory syncytial virus (RSV) infection in mice

2023-1-1

Dexmedetomidine protects against Ropivacaine-induced neuronal pyroptosis via the Nrf2/HO-1 pathway

2023-1-1

Melatonin therapy reverses lead exposure-induced testicular damage in rats despite the lack of effect on serum testosterone levels

2023-1-1

Exposure to bisphenol A or its phenolic analogs during early life induces different types of anxiety-like behaviors after maturity in male mice

2023-1-1