研飞ivySCI (青藤学术）

Pharmaceutical Research

短名	Pharm Res
Journal Impact	3.42
国际分区	PHARMACOLOGY & PHARMACY(Q2)
期刊索引	SCI Q2中科院 3 区

ISSN	0724-8741, 1573-904X
h-index	229
国内分区	医学(3区)医学化学综合(3区)医学药学(3区)

《药物研究》是美国药物科学家协会的官方期刊，致力于发表以机制为基础、以假设为驱动的新研究，并解决药物发现、开发和监管方面的重大问题。目前感兴趣的领域包括但不限于：-（预）配方工程和加工-计算生物药剂学-药物递送和靶向-分子生物药剂学和药物处置（包括细胞和分子药理学）-药代动力学、药效学和药物遗传学。研究可能涉及非临床和临床研究，并利用体外和体内方法。欢迎研究药物小分子、药物固体材料（包括生物材料、聚合物和纳米颗粒）生物技术产品（包括基因、多肽、蛋白质和疫苗）和基因工程细胞。

期刊主页投稿网址

涉及主题	化学生物医学生物化学有机化学遗传学药理学物理内科学材料科学工程类色谱法生物信息学内分泌学量子力学心理学化学工程核磁共振复合材料纳米技术精神科
出版信息	出版商: Springer，出版周期: Monthly，期刊类型: journal
基本数据	创刊年份: 1984，原创研究文献占比: 83.39%，自引率:2.90%， Gold OA占比: 22.17%
平均审稿周期	网友分享经验：平均3.0个月
平均录用比例	网友分享经验：较易

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Retraction Note: Verapamil Inhibits Ser202/Thr205 Phosphorylation of Tau by Blocking TXNIP/ROS/p38 MAPK Pathway

2024-9-11

The Use of Systemically Absorbed Drugs to Explore An In Vitro Bioequivalence Approach For Comparing Non-Systemically Absorbed Active Pharmaceutical Ingredients in Drug Products For Use in Dogs

2024-9-9

Correction: Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part I: In Vitro Testing and Characterization

2024-9-5

Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part II: In vivo Efficacy Testing in a Rabbit Surfactant Washout Model

2024-9-5

Current Approaches to Design Space Development and Regulatory Applications for Drug Products: Findings from the IQ Utilization of Design Space for Filings Working Group Survey

2024-9-4

A Novel Size Exclusion Chromatography Method for the Analysis of Monoclonal Antibodies and Antibody–drug Conjugates by Using Sodium Iodide in the Mobile Phase

2024-9-4

MR Molecular Image Guided Treatment of Pancreatic Cancer with Targeted ECO/miR-200c Nanoparticles in Immunocompetent Mouse Tumor Models

2024-8-28

Current Insights into CAR T-Cell-Based Therapies for Myelodysplastic Syndrome

2024-8-26

Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum

2024-8-22

Acceleration of Final Residual Solvent Extraction From Poly(lactide-co-glycolide) Microparticles

2024-8-15

Formulation and Validation of an Extended Sigmoid Emax Model in Pharmacodynamics

2024-8-14

Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method

2024-8-13

Rapid Synthesis and Evaluation of Resveratrol-Piperazine Cocrystals by Ultrasound and Microwave Methods

2024-8-7

Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles

2024-8-7

Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part I: In Vitro Testing and Characterization

2024-8-7

Correction: Comment on the article: In vivo Pharmacokinetics/Pharmacodynamics Profiles for Appropriate Doses of Cefditoren pivoxil against S. pneumoniae in Murine Lung-Infection Model

2024-8-6

Accelerated Development of Pharmaceuticals Past, Present, and Future

2024-8-6

Therapeutic Strategies to Combat Increasing Rates of Multidrug Resistant Pathogens

2024-8-6

Comparison of Relative Activity versus Relative Expression Factors (RAF versus REF) in Predicting Glucuronidation Mediated Drug Clearance Using Recombinant UGTs

2024-8-1

Machine Learning Prediction of On/Off Target-driven Clinical Adverse Events

2024-8-1

Multi-component Crystal Strategy for Improving Water Solubility and Antifungal Activity of Climbazole

2024-7-29

The Impact of Annealing Methods on the Encapsulating Structure and Storage-Stability of Freeze-Dried Pellets of Probiotic Bacteria

2024-7-29

Tolterodine Tartrate Loaded Cationic Elastic Liposomes for Transdermal Delivery: In Vitro, Ex Vivo, and In Vivo Evaluations

2024-7-24

Cytopathic Effect Detection and Clonal Selection using Deep Learning

2024-7-24

Iron Reduces the Trafficking of Fatty Acids from Human Immortalised Brain Microvascular Endothelial Cells Through Modulation of Fatty Acid Transport Protein 1 (FATP1/SLC27A1)

2024-7-24

Evaluation of In Vitro Metabolism- and Transporter-Based Drug Interactions with Sunscreen Active Ingredients

2024-7-24

Fluorinated PAMAM-Arginine Carrier Prodrugs for pH-Sensitive Sustained Ibuprofen Delivery

2024-7-24

The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice

2024-7-24

Letter to the Editor

2024-7-13

High-Throughput Fluorometric Assay For Quantifying Polysorbate In Biopharmaceutical Products Using Micelle Activated Fluorescence Probe N-Phenyl-1-Naphthylamine

2024-7-2

Topical Semisolid Drug Product Critical Quality Attributes with Relevance to Cutaneous Bioavailability and Pharmacokinetics: Part I—Bioequivalence of Acyclovir Topical Creams

2024-7-1

Distribution Clearance: Significance and Underlying Mechanisms

2024-7-1

Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System

2024-7-1

Insight into the Manipulation Mechanism of Polymorphic Transformation by Polymers: A Case of Cimetidine

2024-7-1

Duo photoprotective effect via silica-coated zinc oxide nanoparticles and Vitamin C nanovesicles composites

2024-7-1

Role of Charge Heterogeneity on Physical Stability of Monoclonal Antibody Biotherapeutic Products

2024-6-28

Effect of Apolipoprotein E isoforms on the Abundance and Function of P-glycoprotein in Human Brain Microvascular Endothelial Cells

2024-6-27

Stability of Protein Pharmaceuticals: Recent Advances

2024-6-27

A Combination of Machine Learning and PBPK Modeling Approach for Pharmacokinetics Prediction of Small Molecules in Humans

2024-6-25

Inflammation-Responsive Mesoporous Silica Nanoparticles with Synergistic Anti-inflammatory and Joint Protection Effects for Rheumatoid Arthritis Treatment

2024-6-25

Correction: Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery

2024-6-25

Application of the Finite Absorption Time (F.A.T.) Concept in the Assessment of Bioequivalence

2024-6-19

Predictive Value of Vancomycin AUC24/MIC Ratio for 30-day Mortality in Patients with Severe or Complicated Methicillin-Resistant Staphylococcus aureus Infections: A Multicenter Retrospective Study

2024-6-17

Phase Transitions Involving Channel Hydrates of a New Pharmaceutical Compound

2024-6-13

Effect of mPEG-PLGA on Drug Crystallinity and Release of Long-Acting Injection Microspheres: In Vitro and In Vivo Perspectives

2024-6-1

Translation from Preclinical Research to Clinical Trials: Transdermal Drug Delivery for Neurodegenerative and Mental Disorders

2024-6-1

Laplace Transform Based Modeling of Drug Delivery with Reversible Drug Binding in a Multilayer Tissue

2024-6-1

Developing Engineered Nano-Immunopotentiators for the Stimulation of Dendritic Cells and Inhibition and Prevention of Melanoma

2024-6-1

Enhancing the Stability, Solubility, and Antioxidant Activity of Cinchonine through Pharmaceutical Cocrystallization

2024-6-1

Topical Solution for Retinal Delivery: Bevacizumab and Ranibizumab Eye Drops in Anti-Aggregation Formula (AAF) in Rabbits

2024-6-1

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Pharmaceutical Research

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最新文章

Retraction Note: Verapamil Inhibits Ser202/Thr205 Phosphorylation of Tau by Blocking TXNIP/ROS/p38 MAPK Pathway

The Use of Systemically Absorbed Drugs to Explore An In Vitro Bioequivalence Approach For Comparing Non-Systemically Absorbed Active Pharmaceutical Ingredients in Drug Products For Use in Dogs

Correction: Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part I: In Vitro Testing and Characterization

Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part II: In vivo Efficacy Testing in a Rabbit Surfactant Washout Model

Current Approaches to Design Space Development and Regulatory Applications for Drug Products: Findings from the IQ Utilization of Design Space for Filings Working Group Survey

A Novel Size Exclusion Chromatography Method for the Analysis of Monoclonal Antibodies and Antibody–drug Conjugates by Using Sodium Iodide in the Mobile Phase

MR Molecular Image Guided Treatment of Pancreatic Cancer with Targeted ECO/miR-200c Nanoparticles in Immunocompetent Mouse Tumor Models

Current Insights into CAR T-Cell-Based Therapies for Myelodysplastic Syndrome

Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum

Acceleration of Final Residual Solvent Extraction From Poly(lactide-co-glycolide) Microparticles

Formulation and Validation of an Extended Sigmoid Emax Model in Pharmacodynamics

Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method

Rapid Synthesis and Evaluation of Resveratrol-Piperazine Cocrystals by Ultrasound and Microwave Methods

Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles

Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part I: In Vitro Testing and Characterization

Correction: Comment on the article: In vivo Pharmacokinetics/Pharmacodynamics Profiles for Appropriate Doses of Cefditoren pivoxil against S. pneumoniae in Murine Lung-Infection Model

Accelerated Development of Pharmaceuticals Past, Present, and Future

Therapeutic Strategies to Combat Increasing Rates of Multidrug Resistant Pathogens

Comparison of Relative Activity versus Relative Expression Factors (RAF versus REF) in Predicting Glucuronidation Mediated Drug Clearance Using Recombinant UGTs

Machine Learning Prediction of On/Off Target-driven Clinical Adverse Events

Multi-component Crystal Strategy for Improving Water Solubility and Antifungal Activity of Climbazole

The Impact of Annealing Methods on the Encapsulating Structure and Storage-Stability of Freeze-Dried Pellets of Probiotic Bacteria

Tolterodine Tartrate Loaded Cationic Elastic Liposomes for Transdermal Delivery: In Vitro, Ex Vivo, and In Vivo Evaluations

Cytopathic Effect Detection and Clonal Selection using Deep Learning

Iron Reduces the Trafficking of Fatty Acids from Human Immortalised Brain Microvascular Endothelial Cells Through Modulation of Fatty Acid Transport Protein 1 (FATP1/SLC27A1)

Evaluation of In Vitro Metabolism- and Transporter-Based Drug Interactions with Sunscreen Active Ingredients

Fluorinated PAMAM-Arginine Carrier Prodrugs for pH-Sensitive Sustained Ibuprofen Delivery

The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice

Letter to the Editor

High-Throughput Fluorometric Assay For Quantifying Polysorbate In Biopharmaceutical Products Using Micelle Activated Fluorescence Probe N-Phenyl-1-Naphthylamine

Topical Semisolid Drug Product Critical Quality Attributes with Relevance to Cutaneous Bioavailability and Pharmacokinetics: Part I—Bioequivalence of Acyclovir Topical Creams

Distribution Clearance: Significance and Underlying Mechanisms

Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System

Insight into the Manipulation Mechanism of Polymorphic Transformation by Polymers: A Case of Cimetidine

Duo photoprotective effect via silica-coated zinc oxide nanoparticles and Vitamin C nanovesicles composites

Role of Charge Heterogeneity on Physical Stability of Monoclonal Antibody Biotherapeutic Products

Effect of Apolipoprotein E isoforms on the Abundance and Function of P-glycoprotein in Human Brain Microvascular Endothelial Cells

Stability of Protein Pharmaceuticals: Recent Advances

A Combination of Machine Learning and PBPK Modeling Approach for Pharmacokinetics Prediction of Small Molecules in Humans

Inflammation-Responsive Mesoporous Silica Nanoparticles with Synergistic Anti-inflammatory and Joint Protection Effects for Rheumatoid Arthritis Treatment

Correction: Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery

Application of the Finite Absorption Time (F.A.T.) Concept in the Assessment of Bioequivalence

Predictive Value of Vancomycin AUC24/MIC Ratio for 30-day Mortality in Patients with Severe or Complicated Methicillin-Resistant Staphylococcus aureus Infections: A Multicenter Retrospective Study

Phase Transitions Involving Channel Hydrates of a New Pharmaceutical Compound

Effect of mPEG-PLGA on Drug Crystallinity and Release of Long-Acting Injection Microspheres: In Vitro and In Vivo Perspectives

Translation from Preclinical Research to Clinical Trials: Transdermal Drug Delivery for Neurodegenerative and Mental Disorders

Laplace Transform Based Modeling of Drug Delivery with Reversible Drug Binding in a Multilayer Tissue

Developing Engineered Nano-Immunopotentiators for the Stimulation of Dendritic Cells and Inhibition and Prevention of Melanoma

Enhancing the Stability, Solubility, and Antioxidant Activity of Cinchonine through Pharmaceutical Cocrystallization

Topical Solution for Retinal Delivery: Bevacizumab and Ranibizumab Eye Drops in Anti-Aggregation Formula (AAF) in Rabbits

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