Annual Review of Biophysics and Biophysical Chemistry

W L Mattice

Annu Rev Biophys Biophys Chem

The beta-Sheet to Coil Transition

β-折叠到无规卷曲的转变

Reaction mechanisms in chemistry and biochemistry involve structural change, not merely static structure (1). These structural changes can be very rapid, spanning the time range from femtoseconds to seconds and above. We have developed and applied timeresolved X-ray crystallography(2,3) to monitor directly the changes in electron density and hence in atomic location, as biological macromolecules respond to light.

K Moffat

Time-Resolved Macromolecular Crystallography

时间分辨大分子晶体学

Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems employ the dual RNA–guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific ...Read More

S McLaughlin

The Electrostatic Properties of Membranes

膜的静电特性

P L Privalov

Thermodynamic Problems of Protein Structure

蛋白质结构的热力学问题

D L Beveridge

F M DiCapua

Free Energy Via Molecular Simulation: Applications to Chemical and Biomolecular Systems

分子模拟自由能：化学与生物分子系统的应用

S Karlin

P Bucher

V Brendel

S F Altschul

Statistical Methods and Insights for Protein and DNA Sequences

蛋白质和DNA序列的统计方法与见解

PERSPECTIVES AND OVERVIEW...... ...... . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . .. ......... . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 INSTRUMENTATION AND THEORETICAL BACKGROUND 8 1 Resolution . . . ..... . . . . . .... .. ......... . . . . . . . . . . . . . . . ... . . . . . . . . ...... . . . . . . . . . . 8 1 Servo System, Scan Devices, and Scan Modes ...... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....... . . . . 83 Probes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 Scanning Tunneling Microscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . .. . . . . . . . . . . . . . . 86 Scanning Force Microscopy . . . . ....... . . . . . . . . . . . . . . ... . . . . ... . . . . ..... . . . . 87 SP M for Biological Applications . . . . . . .. . . . . . . . . . . . . . . ....... . . . .. . . 87 SAMPLE PREPARATION FOR SPM . ........ . . . . ... . . . . . . . . . . ....... . . . . . . . . . . . . . . . . . . . 88 Protein Structure ... .... . ....... ... ...... . . . . . . . . ........ . . . . . . . . . . .. . ........ . . . . . . . . . . . . 88 Preparation Artifacts During Immobilization and Dehydration .. . . . . . . ........ 88 Specimen Supports . . . . . . . . . . . . . . . .... . . . . . . . . . . . . . . ..... 89 APPLICATIONS .... . . . . ........ . . . . . . . ......... . . . . . . . . . . . . . . . . ......... . . . . . . . . . . ........ . . . . . . 90 Scanning Tunneling Microscopy ... . . . . ......... .. ...... . . . ......... . . . . . . . . . . . . . . . 90 Scanning Force Microscopy . . . . . . . . ........ . . . . . . . . . ...... . . . . . . 100 CONCLUSIONS AND PROSPECTS . . . . . . . . . . . . . ..... . . . . . . . . . . . .... . . . . . .. . . . . ... . . . 102

A Engel

Biological Applications of Scanning Probe Microscopes

扫描探针显微镜的生物学应用

W. Stühmer

Structure-Function Studies of Voltage-Gated Ion Channels

电压门控离子通道的结构-功能研究

H S Chan

K A Dill

Polymer Principles in Protein Structure and Stability

蛋白质结构与稳定性中的聚合物原理

R A Mathies

S W Lin

J B Ames

W T Pollard

From Femtoseconds to Biology: Mechanism of Bacteriorhodopsin's Light-Driven Proton Pump

从飞秒到生物学：细菌视紫红质光驱动质子泵的机制

出版信息	出版商: Annual Reviews Inc.，出版周期: ，期刊类型: journal，开源期刊: 否
基本数据	创刊年份: 1985，原创研究文献占比: ，自引率:， Gold OA占比:

Annual Review of Biophysics and Biophysical Chemistry

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