Effect of protein binding on the pharmacokinetics of the six substrates in the Basel phenotyping cocktail in healthy subjects and patients with liver cirrhosis

2024-11-1

Formulation and investigation of differently charged β-cyclodextrin-based meloxicam potassium containing nasal powders

2024-11-1

Chemotherapy drug combinations induced maternal ovarian damage and long-term effect on fetal reproductive system in mice

2024-10-1

Relevance of distinctions and parallels between the US and EU guidelines for determination of comparative effectiveness and safety of the orally inhaled drug products

2024-10-1

Editorial Board

2024-10-1

Joint use of population pharmacokinetics and machine learning for prediction of valproic acid plasma concentration in elderly epileptic patients

2024-10-1

The potential of enteroids derived from children and adults to study age-dependent differences in intestinal CYP3A4/5 metabolism

2024-10-1

Do Chinese HIV-infected adult patients with altered renal function need to adjust tenofovir disoproxil fumarate dosage? A population pharmacokinetics analysis

2024-10-1

Impact of advanced age on the gastric emptying of water under fasted and fed state conditions

2024-10-1

New mathematical model from dynamic dissolution rate tests

2024-10-1

PL3 CendR peptide shows specific uptake in cultured Y79 retinoblastoma cells with nucleolar accumulation

2024-10-1

Comparative inhibition by oral bilastine, parenteral dexchlorpheniramine, and a new bilastine parenteral (i.v. and i.m.) formulation of histamine-induced wheal and flare response: a randomised phase I trial

2024-9-1

Association of genetic variations of 3′-UTR in clopidogrel pharmacokinetic-relevant genes with clopidogrel response in Han Chinese patients with coronary artery disease

2024-9-1

Novel analytical solutions for convolution in compartmental pharmacokinetic models and application to non-bioequivalent formulations

2024-9-1

CYP2E1 mediated advanced oxidation protein products exacerbate acetaminophen induced drug-derived liver injury in vitro and in vivo

2024-9-1

Experimental and model-based approach to evaluate solvent effects on the solubility of the pharmaceutical artemisinin

2024-9-1

Influence of particle diameter on aerosolization performance and release of budesonide loaded mesoporous silica particles

2024-9-1

Preparation of nanoparticle and nanoemulsion formulations containing repaglinide and determination of pharmacokinetic parameters in rats

2024-9-1

Material compatibility and processing challenges in droplet deposition modelling additive manufacturing: A study on pharmaceutical excipients Polyvinylpyrrolidone/vinyl acetate (PVP/VA) and Polycaprolactone (PCL)

2024-9-1

Analyzing the Distribution of Progression-Free Survival for Combination Therapies: A Study of Model-Based Translational Predictive Methods in Oncology

2024-9-1

Investigation of real-life drug intake behaviour in older adults and geriatric patients in Northern Germany – a biopharmaceutical perspective.

2024-9-1

Safety, tolerability, and pharmacokinetic of HY0721 in Chinese healthy subjects: A first-in-human randomized, double-blind, placebo-controlled dose escalation phase I study

2024-9-1

Optimization and evaluation of a chitosan-coated PLGA nanocarrier for mucosal delivery of Porphyromonas gingivalis antigens

2024-9-1

Freeze-drying cycle optimization of an amorphous solid dispersion of resveratrol

2024-9-1

First-In-Human Study on Pharmacokinetics, Safety, and Tolerability of Single and Multiple Escalating Doses of PA9159 Nasal Spray, a Highly Potent Glucocorticoid in Healthy Chinese Volunteers

2024-9-1

The environmental burden of inhalation

2024-9-1

Mucoadhesive in situ nasal gel of amoxicillin trihydrate for improved local delivery: ex vivo mucosal permeation and retention studies

2024-9-1

Absorption, Distribution, Metabolism, and Excretion of Tirzepatide in Humans, Rats, and Monkeys

2024-9-1

Predictions of biorelevant solubility change during dispersion and digestion of lipid-based formulations

2024-9-1

Development of Imiquimod-induced HaCaT-THP-1 co-culture for modeling of psoriasis

2024-9-1

Mechanistic insights into carvedilol's potential protection against doxorubicin-induced cardiotoxicity

2024-9-1

Preincubation-dependent inhibition of organic anion transporting polypeptide 2B1

2024-9-1

Spray drying of a zinc complexing agent for inhalation therapy of pulmonary fibrosis

2024-9-1

Novel tetrahydroquinoline derivatives induce ROS-mediated apoptosis in glioblastoma cells

2024-9-1

Thermo-activated in situ rectal gel preparation for Ibuprofen using eutectic mixture.

2024-9-1

The metabolic profiles of endogenous and exogenous substances in a poor metabolizer of humanized CYP2D6 model

2024-9-1

Comparison of ionizable lipids for lipid nanoparticle mediated DNA delivery

2024-9-1

Ultrasound-mediated nanobubbles loaded with STAT6 siRNA inhibit TGF-β1-EMT axis in LUSC cells via overcoming the polarization of M2-TAMs

2024-9-1

IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing

2024-9-1

Cutaneous Pharmacokinetics-Based Bioequivalence: A Clinical Dermal Open Flow Microperfusion Verification Study Using Lidocaine and Prilocaine Combination Topical Products

2024-9-1

In vivo permeation of 2-phenoxyethanol in human skin

2024-8-24

Genetic polymorphisms and their association with methotrexate polyglutamates during maintenance treatment in Korean children and young adults with acute lymphoblastic leukemia

2024-8-17

Human enteroid monolayers as a potential alternative for Ussing chamber and Caco-2 monolayers to study passive permeability and drug efflux

2024-8-16

Sonophoresis mediated diffusion of caffeine loaded Transcutol® enriched cerosomes for topical management of cellulite

2024-8-8

Development, optimization and ex-vivo evaluation of a transdermal formulation containing trazodone

2024-8-7

In vitro permeation testing for the evaluation of drug delivery to the skin

2024-8-7

Edaravone N-benzyl pyridinium derivatives: BACE-1 inhibition, kinetics and in silico binding pose determination

2024-8-3

Analyzing Parametric Influences Driving Age-Associated Changes in Absorption using a PBPK-GSA Approach

2024-8-1

Corrigendum to “ Small molecules modified mesoporous silica nanoparticles orally deliver indomethacin with synergistic effect” [European Journal of Pharmaceutical Sciences 195 (2024) 106719]

2024-8-1

Butein Derivatives Prevent Obesity and Improve Insulin Resistance through the Induction of Energy Expenditure in High-Fat Diet-Fed Obese Mice

2024-8-1