Prefrontal cortex astrocytes in major depressive disorder: exploring pathogenic mechanisms and potential therapeutic targets

2024-9-14

Revising pathogenesis of AP1S1-related MEDNIK syndrome: a missense variant in the AP1S1 gene as a causal genetic lesion

2024-9-13

Retraction Note: Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells

2024-9-6

Exosomal miR-21-5p derived from endometrial stromal cells promotes angiogenesis by targeting TIMP3 in ovarian endometrial cysts

2024-9-4

Epigenetic profiles in blood and adipose tissue: identifying strong correlations in morbidly obese and non-obese patients

2024-9-3

Current treatment of Psoriasis triggered by Cytokine Storm and future immunomodulation strategies

2024-8-30

TRAP1 modulates mitochondrial biogenesis via PGC-1α/TFAM signalling pathway in colorectal cancer cells

2024-8-29

Endoplasmic reticulum stress induces hepatic steatosis through interaction between PPARα and FoxO6 in vivo and in vitro

2024-8-28

Protective role of M3 muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury

2024-8-22

New CRISPR/Cas9-based Fgfr2C361Y/+ mouse model of Crouzon syndrome exhibits skull and behavioral abnormalities

2024-8-19

New insights into the mechanisms and therapeutic strategies of chondrocyte autophagy in osteoarthritis

2024-8-15

β-Adrenergic blockade attenuates adverse adipose tissue responses after burn

2024-8-15

WNT2B high‑expressed fibroblasts induce the fibrosis of IBD by promoting NK cells secreting IL-33

2024-8-13

Oral pyrophosphate protects Abcc6-/- mice against vascular calcification induced by chronic kidney disease

2024-8-13

The caspase-inhibitor Emricasan efficiently counteracts cisplatin- and neomycin-induced cytotoxicity in cochlear cells

2024-8-7

Structure-based humanization of a therapeutic antibody for multiple myeloma

2024-7-25

MicroRNAs role in telomere length maintenance and telomerase activity in tumor cells

2024-7-23

Effect of α7 nAChR-autophagy axis of deciduous tooth pulp stem cells in regulating IL-1β in the process of physiological root resorption of deciduous teeth

2024-7-13

Neutrophil-secreted S100A8/A9 participates in fatty liver injury and fibrosis by promoting myofibroblast migration

2024-7-12

Metformin improves cognitive dysfunction through SIRT1/NLRP3 pathway–mediated neuroinflammation in db/db mice

2024-7-2

The role and mechanism of heme oxygenase-1 in arrhythmias

2024-6-28

Aging- and alcohol-associated spatial transcriptomic signature in mouse acute pancreatitis reveals heterogeneity of inflammation and potential pathogenic factors

2024-6-28

Molecular targets in bone cancer pain: a systematic review of inflammatory cytokines

2024-6-28

PD-1/PD-L1 axis: implications in immune regulation, cancer progression, and translational applications

2024-6-27

CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation

2024-6-21

Sex hormone binding globulin (SHBG) modulates mitochondrial dynamics in PPARγ-depleted equine adipose derived stromal cells

2024-6-14

Exploring the role of tRNA-derived small RNAs (tsRNAs) in disease: implications for HIF-1 pathway modulation

2024-6-8

Removal of GIT lesions and the role of impedance of the injection solution—an innovative approach to known methods

2024-6-3

Tumor-derived extracellular vesicle proteins as new biomarkers and targets in precision oncology

2024-5-30

Research progress and application of liver organoids for disease modeling and regenerative therapy

2024-5-28

Sphingosine is involved in PAPTP-induced death of pancreas cancer cells by interfering with mitochondrial functions

2024-5-23

Mitochondria targeted esculetin administration improves insulin resistance and hyperglycemia-induced atherosclerosis in db/db mice

2024-5-17

Non-invasive biomarkers prognostic of decompensation events in NASH cirrhosis: a systematic literature review

2024-5-16

Loss-of-function mutation in DDX53 associated with hereditary spastic paraplegia-like disorder

2024-5-16

Role and molecular mechanism of NOD2 in chronic non-communicable diseases

2024-5-14

PCDH11X mutation as a potential biomarker for immune checkpoint therapies in lung adenocarcinoma

2024-5-13

Blocking H1R signal aggravates atherosclerosis by promoting inflammation and foam cell formation

2024-5-11

Mechanism of efferocytosis in atherosclerosis

2024-5-10

Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization

2024-5-2

Mechanistic complement of autosomal dominant polycystic kidney disease: the role of aquaporins

2024-4-26

Analysis of the action mechanisms and targets of herbal anticonvulsants highlights opportunities for therapeutic engagement with refractory epilepsy

2024-4-24

The role of annexins in central nervous system development and disease

2024-4-19

The role of the immunosuppressive PD-1/PD-L1 checkpoint pathway in the aging process and age-related diseases

2024-4-11

Abnormal protein SUMOylation in liver disease: novel target for therapy

2024-4-3

Metabolomic profiling of maternal plasma identifies inverse associations of acetate and urea with anti-SARS-CoV-2 antibody titers following COVID-19 vaccination during pregnancy

2024-4-3

Pathogenic effects of Leu200Pro and Arg387His VRK1 protein variants on phosphorylation targets and H4K16 acetylation in distal hereditary motor neuropathy

2024-3-30

Ischemic stroke and diabetes: a TLR4-mediated neuroinflammatory perspective

2024-3-28

An Hsp70 promoter–based mouse for heat shock–induced gene modulation

2024-3-16

Blockade of aryl hydrocarbon receptor restricts omeprazole-induced chronic kidney disease

2024-3-8

How calorie restriction slows aging: an epigenetic perspective

2024-3-8