Thiol-Specific Linkers for the Synthesis of Oligonucleotide Conjugates via Metal-Free Thiol–Ene Click Reaction

2024-9-12

Scission-Enhanced Molecular Imaging (SEMI)

2024-9-10

Facile Rebridging Conjugation Approach to Attain Monoclonal Antibody-Targeted Nanoparticles with Enhanced Antigen Binding and Payload Delivery

2024-9-10

In Situ Polymerization for Manufacture of Multifunctional Delivery Systems for Transcellular Delivery of Nucleic Acids

2024-9-3

Light-Activated Molecular Purification (LAMP) of Recombinant Proteins

2024-9-2

Nanosized Porphyrin-Containing Covalent Organic Polymer to Enhance Ferroptosis in Photodynamic Treatment of Tumor Cells via Glutathione Depletion

2024-8-30

Enhancing Cell Aggregation and Migration via Double-Click Cross-Linking with Azide-Modified Hyaluronic Acid

2024-8-30

Lipid Nanoparticles for Brain Tumor Theranostics: Challenges and Status

2024-8-29

Chemoselective Reagents for the Traceless Bioreversible Modification of Native Proteins

2024-8-29

Epidermal Growth Factor Receptor (EGFR) Inhibitors Screened from Autodisplayed Fv-Antibody Library

2024-8-28

Cyclohexanediamine Triazole (CHDT) Functionalization Enables Labeling of Target Molecules with Al¹⁸F/⁶⁸Ga/¹¹¹In

2024-8-26

Preclinical Evaluation of a PSMA Aptamer-Based Bifunctional PET and Fluorescent Probe

2024-8-26

Gastrodin Liposomes Block Crosstalk between Astrocytes and Glioma Cells via Downregulating Cx43 to Improve Antiglioblastoma Efficacy of Temozolomide

2024-8-24

Sortase-Mediated Site-Specific Conjugation to Prepare Fluorine-18-Labeled Nanobodies

2024-8-22

Issue Editorial Masthead

2024-8-21

A Novel Confocal Scanning Protein–Protein Interaction Assay (PPI-CONA) Reveals Exceptional Selectivity and Specificity of CC0651, a Small Molecule Binding Enhancer of the Weak Interaction between the E2 Ubiquitin-Conjugating Enzyme CDC34A and Ubiquitin

2024-8-21

Issue Publication Information

2024-8-21

Synthesis of Amphiphilic Amino Poly-Amido-Saccharide and Poly(lactic) Acid Block Copolymers and Fabrication of Paclitaxel-Loaded Mucoadhesive Nanoparticles

2024-8-19

Data-Driven Design of Novel Polymer Excipients for Pharmaceutical Amorphous Solid Dispersions

2024-8-16

Click Chemistry Enables [⁸⁹Zr]Zr-DOTA Radioimmunoconjugation for Theranostic ⁸⁹Zr-immunoPET

2024-8-16

Site-Selective Antibody Conjugation with Dibromopyrazines

2024-8-16

Regiospecific Coelenterazine Analogs for Bioassays and Molecular Imaging

2024-8-15

A New Age of Drug Delivery: A Comparative Perspective of Ferritin–Drug Conjugates (FDCs) and Antibody–Drug Conjugates (ADCs)

2024-8-12

Development of a Self-Luminescent Living Bioreactor for Enhancing Photodynamic Therapy in Breast Cancer

2024-8-9

Bioconjugates for Cancer Prevention: Opportunities for Impact

2024-8-8

Discovery Small-Molecule p300 Inhibitors Derived from a Newly Developed Indazolone-Focused DNA-Encoded Library

2024-8-8

7-Deaza-2′-deoxyisoguanosine, a Noncanonical Nucleoside for Nucleic Acid Code Expansion and New DNA Constructs: Nucleobase Functionalization of Inverse Watson–Crick and Purine–Purine Base Pairs

2024-8-1

Synthesis and Structure Optimization of Star Copolymers as Tunable Macromolecular Carriers for Minimal Immunogen Vaccine Delivery

2024-7-31

Early Detection and Noninvasive Staging of Kidney Dysfunction by a PEGylated Conventional Fluorophore via GFR-Sensitive Renal Transport

2024-7-30

Control of Solid-Supported Intra- vs Interstrand Stille Coupling Reactions for Synthesis of DNA–Oligophenylene Conjugates

2024-7-24

Chemical Synthesis of Interleukin-6 for Mirror-Image Screening

2024-7-23

First-in-Human Evaluation of [¹⁸F]FDOPA Produced by Organo-Photoredox Reactions

2024-7-18

Issue Editorial Masthead

2024-7-17

Issue Publication Information

2024-7-17

Tumor Metabolism: A New Field for the Treatment of Glioma

2024-7-16

Rational Design of Targeted Gold Nanoclusters with High Affinity to Integrin αvβ3 for Combination Cancer Therapy

2024-7-15

Synthetic Amine Linkers for Efficient Sortagging

2024-7-12

Lignin-Based Nanoparticles for Combination of Tumor Oxidative Stress Amplification and Reactive Oxygen Species Responsive Drug Release

2024-7-11

Targeted Protein Degradation (TPD) for Immunotherapy: Understanding Proteolysis Targeting Chimera-Driven Ubiquitin-Proteasome Interactions

2024-7-11

Rational Design of Cyanine-Based Fluorogenic Dimers to Reduce Nonspecific Interactions with Albumin and Lipid Bilayers: Application to Highly Sensitive Imaging of GPCRs in Living Cells

2024-7-10

Microwave-Assisted Synthesis of β-<i>N</i>-Aryl Glycoamphiphiles with Diverse Supramolecular Assemblies and Lectin Accessibility

2024-7-10

AUNP-12 Near-Infrared Fluorescence Probes across NIR-I to NIR-II Enable <i>In Vivo</i> Detection of PD-1/PD-L1 Axis in the Tumor Microenvironment

2024-7-9

Photoinduced Charge Centralization Quenches the Fluorescence of Conjugation-Fused Tetrazine Labels with Red-to-Near-Infrared Emissions

2024-7-4

Permutational Encoding Strategy Accelerates HIT Validation from Single-Stranded DNA-Encoded Libraries

2024-7-4

Size-Dependent Glioblastoma Targeting by Polymeric Nanoruler with Prolonged Blood Circulation

2024-7-3

Synthesis, Characterization, and Potential Usefulness in Liver Function Assessment of Novel Bile Acid Derivatives with Near-Infrared Fluorescence (NIRBAD)

2024-7-3

Development of an FAP-Targeted PET Probe Based on a Novel Quinolinium Molecular Scaffold

2024-7-2

Efficient Chemical Synthesis of Multi-Monoubiquitylated and Diubiquitylated Histones by the α-Halogen Ketone-Mediated Strategy

2024-7-2

Oriented Antibody Coupling to an Antifouling Polymer Using Glycan Remodeling for Biosensing by Particle Motion

2024-7-1

Ratiometric Fluorescence Probes for In Situ Imaging of Membrane Tension in Live Cells

2024-6-27