​​​​​​器官移植的当前观点是一个不可或缺的资源，具有来自世界各地的该领域的关键、最新和重要进展。在每个部分的知名客座编辑的带领下，每双月刊《器官移植的最新观点》都提供了对干细胞移植、免疫抑制、耐受诱导以及器官保存和采购等主题的全新见解。该杂志共有 18 个部分，提供了对该领域的方便和全面的回顾，并且会引起研究人员、外科医生和其他医疗保健专业人员的兴趣。

Current Opinion in Organ Transplantation is an essential resource that presents key, up-to-date, and significant advancements in the field from around the world. Each issue, led by renowned guest editors, offers fresh insights on topics such as stem cell transplantation, immunosuppression, tolerance induction, and organ preservation and procurement. The journal consists of 18 sections, providing a convenient and comprehensive overview that will engage researchers, surgeons, and other healthcare professionals.

《Current Opinion in Organ Transplantation》是一个不可或缺的资源，提供来自全球该领域的关键、最新和重要进展。每期由知名客座编辑带领的双月刊，涵盖干细胞移植、免疫抑制、耐受诱导以及器官保存和采购等主题，提供全新的见解。该杂志共有18个部分，方便研究人员、外科医生和其他医疗保健专业人员全面回顾该领域的最新动态。

Current Opinion in Organ Transplantation

Purpose of review This review focuses on more recently emerging rejection phenotypes in the context of time post transplantation and the resulting differential diagnostic challenges. It also discusses how novel ancillary diagnostic tools can potentially increase the accuracy of biopsy-based rejection diagnosis. Recent findings With advances in reducing immunological risk at transplantation and improved immunosuppression treatment renal allograft survival improved. However, allograft rejection remains a major challenge and represent a frequent course for allograft failure. With prolonged allograft survival, novel phenotypes of rejection are emerging, which can show complex overlap and transition between cellular and antibody-mediated rejection mechanisms as well as mixtures of acute/active and chronic diseases. With the emerging complexity in rejection phenotypes, it is crucial to achieve diagnostic accuracy in the individual patient. Summary The prospective validation and adoption of novel molecular and computational diagnostic tools into well defined and appropriate clinical context of uses will improve our ability to accurately diagnose, stage, and grade allograft rejection.

Michael Mengel

Benjamin A. Adam

Emerging phenotypes in kidney transplant rejection

肾移植排斥中的新兴表型

Highlight the importance of acute kidney injury (AKI) among liver transplant candidates, its importance of survival and the vital role of continuous renal replacement therapy (CRRT) as a supportive therapy.

Priya Yenebere

Chandrashekhar A. Kubal

Muhammad Yahya Jan

Role of continuous renal replacement therapy in management of the preliver transplant patient

持续肾脏替代治疗在肝移植前患者管理中的作用

Purpose of review This review summarizes the different instruments for evaluating the psychosocial health of transplant candidates, the evidence demonstrating how these instruments relate to probability of transplant waitlisting and transplant outcomes, and the critical knowledge gaps that exist in the causal pathway between psychosocial health and clinical transplant trajectory. Recent findings The current literature reveals that psychosocial assessments are a common reason for racial and ethnic minorities to be denied access to the transplant list. Given evidence that a lack of clinician consensus exists regarding the definition of, importance of, and reproducibility of psychosocial support evaluations, this facet of the holistic evaluation process may create a unique challenge for already vulnerable patient populations. Though recent evidence shows that psychosocial evaluation scores predict select transplant outcomes, these findings remain inconsistent. Summary Multiple instruments for psychosocial transplant evaluation exist, though the utility of these instruments remains uncertain. As equity becomes an increasingly urgent priority for the transplant system, rigorous interrogation of the causal pathway between psychosocial health and transplant longevity is still needed.

Joy E. Obayemi

Brian I. Shaw

Goni-Katz Greenberg

Jackie Henson

Lisa M. McElroy

Ensuring equity in psychosocial risk assessment for solid organ transplantation: a review

确保实体器官移植心理社会风险评估的公平性：综述

Purpose of review Despite technical and therapeutic advances, only 20–40% of patients with colorectal liver metastases (CRLM) have resectable disease. Historically, the remaining patients with unresectable, liver-only CRLM would receive palliative chemotherapy, with a median survival of 8 months. Recent findings Liver transplantation has emerged as a viable option for selected patients with CRLM. This advancement stems from improved understanding of tumour genomics and biology and better patient selection criteria. The results of recent prospective clinical trials have further ignited enthusiasm for liver transplantation as a viable therapeutic option. Living donor liver transplantation (LDLT) offers several advantages over deceased donor liver transplantation (DDLT) for this disease, including reduced wait-time and optimized timing and coordination of oncologic therapy. On-going LDLT clinical trials have demonstrated favourable outcomes as compared with other liver transplantation indications. However, there is no established consensus or standardization in the implementation of LDLT for CRLM, beyond trials and centre-specific protocols. Summary LDLT is an excellent therapeutic option in highly selected patients with CRLM. Refining prognostic factors and selection criteria will help to further optimize the utility and broaden the acceptance and implementation of LDLT for patients with CRLM.

Luckshi Rajendran

Gonzalo Sapisochin

Mark Cattral

The role of living donor liver transplantation in colorectal cancer liver metastases

活体供肝移植在结直肠癌肝转移中的作用

Purpose of review While prior reviews have assessed barriers to transplantation experienced by patients and their families, they have not summarized how these stakeholders feel about whether and how those barriers impact equity in transplantation. We seek to comprehensively present the literature of patients and family perspectives on disparities in transplant access and potential solutions. Recent findings Some patients and their families report experiences of discrimination, while others from traditionally marginalized groups feel the system is equitable and do not perceive any different treatment as a result of their race/ethnicity, sex, age, religion, or geography. This summary suggests that not all of the disparities observed in transplant access are attributable to systemic or unconscious bias and may be partially alleviated through enhanced education and communication. Summary Lack of understanding and transparency lead to mistrust of organ transplantation, further exacerbating existing disparities. Patient and family engagement is paramount for ensuring the trust of the public who are the source of organs and those who directly benefit from this field. Partnerships between patient advocacy groups, professional societies, and policymakers have the potential to increase transparency while ensuring that the patient voice is represented in any system-level change and assessment.

Rhiannon D. Reed

Jayme E. Locke

Giving a voice to patient and caregiver perspectives on equity in transplantation

在移植中赋予患者和护理者视角以公平的声音

Purpose of review Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape in advanced hepatocellular carcinoma and increasingly are being evaluated in earlier stage disease. Herein we explore the role of ICIs pre-liver transplant for liver cancers. Recent findings Given the high response rates with combination approaches including locoregional treatments, more patients with liver confined disease, without vascular invasion, who have received ICIs are now being rendered eligible for potential liver transplant. This opportunity to expand the population who may benefit from liver transplant has also come with challenges recognizing the global shortage of organs. Post-liver transplant immunosuppression potentially competes with the immune-stimulating effects of ICIs and graft rejection has been a concern. ICIs may provide an opportunity to maintain patients on the waiting list but an understanding of who is likely to benefit is needed, to circumvent possible toxicities. In addition, ICIs are now considered standard of care, in combination with chemotherapy, for advanced cholangiocarcinoma, where the role of liver transplant is evolving. Summary As the eligibility criteria globally for liver transplant in the setting of malignancy continues to expand, the integration of ICIs becomes increasingly important.

Philip Bredin

Zita Galvin

Grainne M. O’Kane

Role of immunotherapy in managing cancers prior to liver transplantation

免疫治疗在肝移植前管理癌症中的作用

Purpose of review Hispanics with limited English proficiency (LEP) face unique challenges in accessing organ transplantation due to limited culturally concordant care and linguistically appropriate resources, leading to disparities in healthcare delivery and transplantation outcomes. This review examines how language barriers affect access to kidney and liver transplant, and highlights the importance of institutional support for quality interpretation services in promoting healthcare equity in transplantation. Recent findings Hispanics experience greater disease burden, but are less likely to receive a transplant compared to non-Hispanic Whites. LEP is a significant barrier to transplantation. Culturally and linguistically concordant interventions, such as the “Hispanic Kidney Transplant Program,” have demonstrated success in improving transplant-related outcomes among Hispanics. However, limited resources affect widespread implementation, and the broad lack of interpretation services in healthcare settings delay timely care in transplantation. Summary Despite some progress demonstrated by culturally and linguistically concordant clinical intervention trials, disparities in transplantation for Hispanics with LEP remain. Enhancing the availability of interpretation services, recruiting and hiring bilingual healthcare professionals, and training healthcare staff to effectively engage with language and interpretation resources are critical to improving health equity. Efforts must prioritize language access and cultural concordance to address the unique challenges faced by Hispanics with LEP.

Abbreviation	Curr. Opin. Organ. Transplant.
Journal Impact	1.68
Quartiles(Global)	TRANSPLANTATION(Q3)

ISSN	1087-2418, 1531-7013
h-index	61

Publication Information	Publisher: Lippincott Williams and Wilkins Ltd.，Publishing cycle: Quarterly，Journal Type: journal，Open Access Journals: No
Basic data	Year of publication: 2001，Proportion of original research papers: 0.00%，Self Citation Rate:5.60%， Gold OA Rate: 5.65%
Average review cycle	网友分享经验：较慢,6-12周
Average recruitment ratio	网友分享经验：一般

Current Opinion in Organ Transplantation

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Emerging phenotypes in kidney transplant rejection

Role of continuous renal replacement therapy in management of the preliver transplant patient

Ensuring equity in psychosocial risk assessment for solid organ transplantation: a review

The role of living donor liver transplantation in colorectal cancer liver metastases

Giving a voice to patient and caregiver perspectives on equity in transplantation

Role of continuous renal replacement therapy in management of the preliver transplant patient

Ensuring equity in psychosocial risk assessment for solid organ transplantation: a review

Role of immunotherapy in managing cancers prior to liver transplantation

Language and cultural concordance to promote equity in organ transplantation for Hispanics with limited English proficiency

The role of living donor liver transplantation in colorectal cancer liver metastases