BIOSCIENCE JOURNAL 是一份跨学科电子期刊，发表农业科学、生物科学和健康科学领域的科学文章。它的使命是传播新知识，同时为国家和世界的科学发展做出贡献。该杂志以英文连续出版。发表的文章中表达的观点和概念是其作者的唯一责任。

The Bioscience Journal is an interdisciplinary electronic journal that publishes scientific articles in the fields of agricultural science, biological science, and health science. Its mission is to disseminate new knowledge and contribute to scientific development both nationally and globally. The journal is published continuously in English, and the views and concepts expressed in the published articles are solely the responsibility of the authors.

《Bioscience Journal》是一份跨学科的电子期刊，专注于农业科学、生物科学和健康科学领域的研究文章。其使命是传播新知识，并为国家和全球的科学发展做出贡献。该期刊以英文持续出版，发表的文章中表达的观点和概念仅代表作者本人。

Bioscience Journal

Intake and performance of goats fed exclusively forages Tifton 85, mulberry or leucaena were simulated to verify which nutrients limit performance.Simulations were performed using the nutritional model similar to Cornell Net Carbohydrate and Protein System (CNCPS) with modifications related to the kinetic attributes of digestion and feed passage.The animal category chosen to perform the simulations was female Saanen goats in growing phase between weaning and mating, with 20 kg of body weight and 150 g of daily gain.The intake of 0.870 kg/day of Tifton 85 was adopted for performance simulations because in this point caused rumen fill and also attended the energy requirement of the animal.For performance simulations of mulberry, the amount of dry matter intake of 0.580 kg/day was adopted based on average intake obtained from the study of Sabino Jr. (1996) and simulations for leucaena used the intake of 0.220 kg/day, corresponding to 30g/100g of dry matter intake that would supply the energy requirement of these female goats.The limiting factor of performance of Saanen female growing goats fed exclusively Tifton 85 or mulberry is the metabolizable protein and not the energy.The intake of leucaena exclusively would be able to supply the requirement of metabolizable protein to promote the target weight gain of 150 g/day.The forages do not present perfect synchronization between carbohydrates and proteins, demonstrated by the positive ammoniacal balance in rumen environment that indicates an excess of nitrogen compounds supplied by these feed.

Simone Pedro da Silva

Marcelo Teixeira Rodrigues

Ricardo Augusto Mendonça Vieira

Márcia Maria Cândido da Silva

Intake and performance simulation of goats fed exclusively tifton 85, mulberry or leucaena

山羊仅饲喂提芬85、桑叶或银合欢的采食量与表现模拟

This study analyzed the effect of mite-specific subcutaneous immunotherapy (SCIT) on patients with allergic rhinitis (AR). We enrolled 98 AR patients visiting our hospital from April 2017 to April 2019 and grouped them in a random number table. The control group (n=49) received conventional treatment for three years. The SCIT used a standardized mite allergen injection for the experimental group (n=49) for three years. The study compared total nasal symptom score (TNSS), daily medication score (DMS), total combined score (TCS), visual analog scale (VAS) score, mini-rhinitis quality of life questionnaire (MiniRQLQ) score, and serum immunoglobulin E (sIgE) level before and after treatment. The overall response rate was higher in the experimental group than in the control group (59.18% vs. 30.61%, p&lt;0.05). After treatment, the experimental group had lower values for TCS and VAS score (p&lt;0.05); motion score; practical problems; nasal, ocular, and other symptoms (p&lt;0.05); and sIgE, Dermatophagoides pteronyssinus (Dp)-sIgE, and Dermatophagoides farinae (Df)-sIgE levels (p&lt;0.05) than the control group. The sIgE, Dp-sIgE, and Df-sIgE levels were lower in the effective group than in the ineffective group (p&lt;0.05). The areas under the ROC curves of IgE, Dp-sIgE, and Df-sIgE and their combination for predicting the therapeutic effect of mite-specific SCIT on AR were 0.839, 0.779, 0.814, and 0.903, respectively. Mite-specific SCIT relieved clinical symptoms and improved the quality of life of AR patients, probably by decreasing the IgE expression level.

Guoyan Sun

Shuangba He

Qingxiang Zhang

Effect of mite-specific subcutaneous immunotherapy on patients with allergic rhinitis

尘螨特异性皮下免疫治疗对过敏性鼻炎患者的影响

Campomanesia sessiliflora (O.Berg) Mattos is a Brazilian native plant species used in a popular medicinal tea for treating gastrointestinal, urinary, and dermatological pathologies. This study evaluated the toxicity of Campomanesia sessiliflora (O.Berg) Mattos via acute and subacute toxicity tests. It also analyzed mutagenic and genotoxic potentials by the micronucleus test, which detects genetic material damage indicating mutagenicity, and the comet assay, which assesses DNA damage levels as a genotoxicity indicator. The plant extract initially originated from the ultrasonic maceration of Campomanesia sessiliflora (O.Berg) Mattos leaves in a hydroethanolic solution. The involved animals were adult Wistar rats. Ten females were available to evaluate acute toxicity and estimate the LD50, receiving a dose of 2000 mg/kg. The subacute toxicity evaluation used 35 females and 35 males divided into seven groups: negative control (saline control – SC), positive control (cyclophosphamide control – CC), 125 mg/kg (125), 250 mg/kg (250), 500 mg/kg (500), 1000 mg/kg (1000), and the satellite group (ST). Genotoxicity and mutagenicity experiments applied bone marrow micronucleus and comet assays. Acute and subacute toxicity tests did not present behavioral, physical, and physiological changes (p≥0.05). Administering the Campomanesia sessiliflora (O.Berg) Mattos extract reduced spleen size in male and female animals, without histopathological changes. However, doses above 500 mg/kg showed significant genotoxic and mutagenic effects in the comet and micronucleus assays compared to the control group. The extract did not exhibit acute or subacute toxicity, but doses higher than 500 mg/kg indicated some level of genotoxicity and mutagenicity.

Anahy Arruda Burigato

Jacenir Vieira da Silva

Larissa Pires Mueller

Flávio Henrique Souza de Araújo

Cláudia Andréa Lima Cardoso

Roosevelt Isaías Carvalho Souza

Agruslávia Rezende de Souza

None Felipe Francisco Bittencourt Junior

Silvia Aparecida Oesterreich

Study of acute and subacute toxicities and genotoxic and mutagenic potentials of the lyophilized extract of Campomanesia sessiliflora (O.Berg) mattos leaves in wistar rats

巴西莓属植物Campomanesia sessiliflora (O.Berg) mattos叶冻干提取物对Wistar大鼠的急性和亚急性毒性及遗传毒性和致突变潜能研究

Ecological niche modeling is a widely used tool to predict species distribution considering current, past, or future climate change scenarios across different geographic areas. Modeling scenarios allow researchers to assess the impacts of climate change on species distribution and identify priority areas for conservation. This study aimed to model the current and future potential distribution of Ceiba glaziovii under different climate change scenarios in Brazil. The MaxEnt algorithm was used to correlate species occurrence points with bioclimatic variables in current and future climate scenarios. Four General Circulation Models (GCMs) from CMIP6 were employed: BCC-CSM2-MR, CNRM-CM6-1, IPSL-CM6A-LR, and MIROC6, considering optimistic and pessimistic projections. The contribution of variables and model accuracy were assessed using the Jackknife statistical test and the Area Under the Curve (AUC) parameter. AUC values for current and future scenarios demonstrated high accuracy. The bioclimatic variables of precipitation and temperature were the main contributors to determining areas with higher habitat suitability. In the future climate scenario, there was a reduction in areas with good climatic suitability for all four GCMs, considering optimistic and pessimistic projections. Among the areas with high habitat suitability, the IPSL-CM6A-1 model in the optimistic projection showed the smallest reduction, while in the pessimistic scenario, all areas with high suitability disappeared. The species' climatic niche is expected to decrease under all tested climate change scenarios. The central areas of the Caatinga and its transition zones exhibit the highest climatic suitability in current and future scenarios and should be prioritized for the species' conservation.

Débora de Melo Almeida

Sara Sebastiana Nogueira

Emanuel Araújo Silva

João Matheus Ferreira de Souza

Antonio Leandro Chaves Gurgel

Alex Nascimento de Sousa

Climate change is expected to reduce the potential distribution of Ceiba glaziovii in Caatinga, the largest area of dry tropical forest in South America

气候变化预计将减少南美洲最大干旱热带森林卡廷加地区中棉木的潜在分布

This study aimed to prepare and apply nanocapsules containing glycerol monolaurate for eradicating Streptococcus mutans biofilms. The interfacial deposition method of the preformed polymer synthesized the nanocapsules characterized for mean diameter, polydispersity index, zeta potential, pH, and morphology by transmission electron microscopy. The microdilution method investigated antimicrobial activity. Crystal violet staining determined biomass quantification and the ability to inhibit biofilm formation. The study also measured exopolysaccharide production and the number of viable colonies. The characterization outcomes indicated acceptable values for the mean diameter 198.1 ± 2, a polydispersity index of 0.087 ± 0.018, a zeta potential of -21.30 ± 2.00 mV, a pH of 6.19 ± 0.12, and typical nanostructure morphology. The evaluations of minimum inhibitory and bactericidal concentrations of glycerol monolaurate (free and nanoencapsulated) revealed their ineffectiveness in inhibiting microorganisms. Only free glycerol monolaurate inhibits S. mutans growth with 125 µg/mL. Biomass, exopolysaccharide content, and viable colonies in the biofilm were analyzed to assess the compounds' ability to inhibit biofilm formation. The tested compounds did not significantly reduce the formed biofilm. Despite unfavorable outcomes of the formulated preparation, further experimentation with a new formulation is encouraged to explore alternative strategies and potential improvements.

Leonardo Quintana Soares Lopes

Rodrigo de Almeida Vaucher

Janice Luehring Giongo

Patrícia Kolling Marquezan

Roberto Christ Vianna Santos

Effect of glycerol monolaurate nanocapsules on Streptococcus mutans biofilm in vitro

甘油单月桂酸酯纳米胶囊对体外变异链球菌生物膜的影响

Barnyardgrass (Echinochloa crus-galli) is one of the most troublesome weeds in irrigated rice cultivation and has increasingly impacted rainfed crops due to the emergence of herbicide-resistant populations. Understanding its germination dynamics is crucial for developing and implementing effective management strategies. Additionally, since barnyardgrass research relies on growing plants from seeds, its dormancy characteristics are of particular interest. The present study aimed to evaluate the influence of postharvest age on barnyardgrass seed germination and the effectiveness of different dormancy-breaking methods in susceptible and herbicide-resistant populations. Germination rate (G), germination speed index (GSI), and seed viability, assessed using the topographic tetrazolium test, were measured in seed lots with four different postharvest ages: two years, one year, two months, and one day postharvest. The seeds were subjected to 15 dormancy-breaking methods, including temperature variation and the use of solutions containing H2SO4, KNO3, and GA3. Seeds that were one or two years old showed germination rates exceeding 90%, regardless of the method used. In contrast, seeds aged two months or one day postharvest only germinated when exposed to 40°C for seven days, with G values of 25.2% and 5.9%, respectively. Both herbicide-susceptible and resistant barnyardgrass populations exhibited similar dormancy levels and responses to dormancy-breaking methods. The results indicate that newly harvested seeds have high dormancy levels, and specific methods are only partially effective in overcoming barnyardgrass seed dormancy.

Alexandre Pisoni

Giliardi Dalazen

Mateus Gallon

Catarine Markus

Aldo Merotto Jr

Evaluation of postharvest age and dormancy-breaking methods on Echinochloa crus-galli seed germination

稻稗种子萌发的采后年龄和打破休眠方法评估

Studies on herbicide selectivity to peanuts detected differences according to the evaluated active ingredient and genotypes. This study analyzed the herbicide selectivity of two genotypes at an early stage. Pre-emergence (trifluralin, pendimethalin, diclosulam, s-metolachlor, imazethapyr + flumioxazin, clomazone, sulfentrazone, and imazapic) and post-emergence (imazapic, bentazon, bentazon + imazamox, clethodim, quizalofop-p-ethyl, cloransulam-methyl, s-metolachlor, lactofen, 2,4-D, and carfentrazone) applications were assessed in 1253 OL and 2133 OL breeding lines. The effects of pre- (PRE) and post-emergence (POST) herbicides were the same for both genotypes, with PRE not affecting seedling emergence and shoot and root dry mass. Diclosulam was among the most selective PRE herbicides, while the clomazone treatment caused only mild damage. All tested POST herbicides caused damage for up to 14 days after application (DAA). At 28 DAA, most herbicides exhibited the same damage as the untreated control. Lactofen caused mild damage (11.8%) without reducing plant height and shoot and root dry mass. Diclosulam, clomazone, and lactofen are unregistered for peanut crops in Brazil, and further studies should test their selectivity for peanut cultivars. Screening studies on selectivity to imazapic, 2,4-D, and carfentrazone are also relevant to identifying sources of tolerance in peanut germplasm.

Abbreviation	Biosci. J.
Journal Impact	0.55
Quartiles(Global)	BIOLOGY(Q4)

ISSN	1516-3725, 1981-3163
h-index	24

Publication Information	Publisher: Universidade Federal de Uberlandia，Publishing cycle: ，Journal Type: journal，Open Access Journals: Yes
Basic data	Year of publication: 2009，Proportion of original research papers: 100.00%，Self Citation Rate:16.70%， Gold OA Rate: 98.10%
Journal Fees	$500Details
Average review cycle	网友分享经验：48 Weeks

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Intake and performance simulation of goats fed exclusively tifton 85, mulberry or leucaena

Effect of mite-specific subcutaneous immunotherapy on patients with allergic rhinitis

Study of acute and subacute toxicities and genotoxic and mutagenic potentials of the lyophilized extract of Campomanesia sessiliflora (O.Berg) mattos leaves in wistar rats

Climate change is expected to reduce the potential distribution of Ceiba glaziovii in Caatinga, the largest area of dry tropical forest in South America

Effect of glycerol monolaurate nanocapsules on Streptococcus mutans biofilm in vitro

Study of acute and subacute toxicities and genotoxic and mutagenic potentials of the lyophilized extract of Campomanesia sessiliflora (O.Berg) mattos leaves in wistar rats

Climate change is expected to reduce the potential distribution of Ceiba glaziovii in Caatinga, the largest area of dry tropical forest in South America

Effect of glycerol monolaurate nanocapsules on Streptococcus mutans biofilm in vitro

Evaluation of postharvest age and dormancy-breaking methods on Echinochloa crus-galli seed germination

Pre-and post-emergence herbicide selectivity in peanuts at an early stage