Cancer Biology and Therapy
| 短名 | cbt |
| Journal Impact | 4.60 |
| 国际分区 | ONCOLOGY(Q2) |
| 期刊索引 | SCI Q2中科院 4 区 |
| ISSN | 1538-4047, 1555-8576 |
| h-index | 130 |
| 国内分区 | 医学(4区)医学肿瘤学(4区) |
Cancer, the second leading cause of death, is a heterogenous group of over 100 diseases. Cancer is characterized by disordered and deregulated cellular and stromal proliferation accompanied by reduced cell death with the ability to survive under stresses of nutrient and growth factor deprivation, hypoxia, and loss of cell-to-cell contacts. At the molecular level, cancer is a genetic disease that develops due to the accumulation of mutations over time in somatic cells. The phenotype includes genomic instability and chromosomal aneuploidy that allows for acceleration of genetic change. Malignant transformation and tumor progression of any cell requires immortalization, loss of checkpoint control, deregulation of growth, and survival. A tremendous amount has been learned about the numerous cellular and molecular genetic changes and the host-tumor interactions that accompany tumor development and progression. It is the goal of the field of Molecular Oncology to use this knowledge to understand cancer pathogenesis and drug action, as well as to develop more effective diagnostic and therapeutic strategies for cancer. This includes preventative strategies as well as approaches to treat metastases. With the availability of the human genome sequence and genomic and proteomic approaches, a wealth of tools and resources are generating even more information. The challenge will be to make biological sense out of the information, to develop appropriate models and hypotheses and to translate information for the clinicians and the benefit of their patients. Cancer Biology & Therapy aims to publish original research on the molecular basis of cancer, including articles with translational relevance to diagnosis or therapy. We will include timely reviews covering the broad scope of the journal. The journal will also publish op-ed pieces and meeting reports of interest. The goal is to foster communication and rapid exchange of information through timely publication of important results using traditional as well as electronic formats. The journal and the outstanding Editorial Board will strive to maintain the highest standards for excellence in all activities to generate a valuable resource.
期刊主页投稿网址| 涉及主题 | 生物医学遗传学内科学化学生物化学癌症研究癌症基因细胞生物学细胞凋亡免疫学病理细胞培养肿瘤科外科细胞 |
| 出版信息 | 出版商: Taylor and Francis Ltd.，出版周期: Monthly，期刊类型: journal |
| 基本数据 | 创刊年份: 2002，原创研究文献占比: 90.16%，自引率:0.00%， Gold OA占比: 79.27% |
| 平均审稿周期 | 网友分享经验：平均2.3月 |
| 平均录用比例 | 网友分享经验：约50% |
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