Integration of estimated regional gene expression with neuroimaging and clinical phenotypes at biobank scale

2024-9-13

Alveolin proteins in the Toxoplasma inner membrane complex form a highly interconnected structure that maintains parasite shape and replication

2024-9-12

Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer’s disease

2024-9-12

Beta-band neural variability reveals age-related dissociations in human working memory maintenance and deletion

2024-9-11

PP1 phosphatase controls both daughter cell formation and amylopectin levels in Toxoplasma gondii

2024-9-10

A how-to guide for code sharing in biology

2024-9-10

The genetic basis of the kākāpō structural color polymorphism suggests balancing selection by an extinct apex predator

2024-9-10

Multisensory perceptual and causal inference is largely preserved in medicated post-acute individuals with schizophrenia

2024-9-10

Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation

2024-9-10

Fixing science means an end to gaming the system

2024-9-9

LXR-dependent enhancer activation regulates the temporal organization of the liver’s response to refeeding leading to lipogenic gene overshoot

2024-9-6

Syllable processing is organized in discrete subregions of the human superior temporal gyrus

2024-9-6

Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapy

2024-9-5

Keeping time: How musical training may boost cognition

2024-9-5

A flexible loop in the paxillin LIM3 domain mediates its direct binding to integrin β subunits

2024-9-4

High temperatures increase the virulence of Vibrio bacteria towards their coral host and competing bacteria via type VI secretion systems

2024-9-4

The coral pathogen Vibrio coralliilyticus uses a T6SS to secrete a group of novel anti-eukaryotic effectors that contribute to virulence

2024-9-3

A dystroglycan–laminin–integrin axis coordinates cell shape remodeling in the developing Drosophila retina

2024-9-3

Phosphorylation of the DNA damage repair factor 53BP1 by ATM kinase controls neurodevelopmental programs in cortical brain organoids

2024-9-3

A taxon-restricted duplicate of Iroquois3 is required for patterning the spider waist

2024-8-29

Inferring the extinction risk of marine fish to inform global conservation priorities

2024-8-29

Hijackers, hitchhikers, or co-drivers? The mysteries of mobilizable genetic elements

2024-8-29

Leveraging social media and other online data to study animal behavior

2024-8-29

The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution

2024-8-27

Molecular connectomics: Placing cells into morphological tissue context

2024-8-26

Swordtail fish hybrids reveal that genome evolution is surprisingly predictable after initial hybridization

2024-8-26

Nuclear reassembly defects after mitosis trigger apoptotic and p53-dependent safeguard mechanisms in Drosophila

2024-8-26

GetGenome: Overcoming inequalities in access to genomics technology

2024-8-26

Fast-spiking interneuron detonation drives high-fidelity inhibition in the olfactory bulb

2024-8-26

Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans

2024-8-23

Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa isolates from cystic fibrosis patients

2024-8-23

Comparative time-series multi-omics analyses suggest H1.2 involvement in anoxic adaptation and cancer resistance

2024-8-23

A somatic view of the genomic impact of mitochondrial endosymbiosis

2024-8-23

The ion channel Anoctamin 10/TMEM16K coordinates organ morphogenesis across scales in the urochordate notochord

2024-8-22

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts

2024-8-22

An empirical appraisal of eLife’s assessment vocabulary

2024-8-22

Cryo-EM structures of the human band 3 transporter indicate a transport mechanism involving the coupled movement of chloride and bicarbonate ions

2024-8-21

Slow-wave sleep drives sleep-dependent renormalization of synaptic AMPA receptor levels in the hypothalamus

2024-8-20

Adenosine diphosphate released from stressed cells triggers mitochondrial transfer to achieve tissue homeostasis

2024-8-20

Distinct melanocyte subpopulations defined by stochastic expression of proliferation or maturation programs enable a rapid and sustainable pigmentation response

2024-8-20

Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKCα-dependent manner

2024-8-19

The conformational plasticity of structurally unrelated lipid transport proteins correlates with their mode of action

2024-8-19

A noninvasive BCG skin challenge model for assessing tuberculosis vaccine efficacy

2024-8-19

AlphaFold2-guided engineering of split-GFP technology enables labeling of endogenous tubulins across species while preserving function

2024-8-19

bHLH transcription factors cooperate with chromatin remodelers to regulate cell fate decisions during Arabidopsis stomatal development

2024-8-16

A rigorous and versatile statistical test for correlations between stationary time series

2024-8-15

Both pathogen and host dynamically adapt pH responses along the intestinal tract during enteric bacterial infection

2024-8-15

Rationalizing risk aversion in science: Why incentives to work hard clash with incentives to take risks

2024-8-15

Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that incur high fitness costs in key pathogenicity traits

2024-8-15

Pam16 and Pam18 were repurposed during Trypanosoma brucei evolution to regulate the replication of mitochondrial DNA

2024-8-15