Antithetical impacts of deleterious LRP1B mutations in non-squamous and squamous NSCLCs on predicting benefits from immune checkpoint inhibitor alone or with chemotherapy over chemotherapy alone: retrospective analyses of the POPLAR/OAK and CHOICE-01 trials

2024-9-12

Genes and proteins expressed at different life cycle stages in the model protist Euplotes vannus revealed by both transcriptomic and proteomic approaches

2024-9-10

Enteromorpha prolifera polysaccharide-Fe (III) complex promotes intestinal development as a new iron supplement

2024-9-9

Can patients with mild non-neoplastic lesions diagnosed at baseline screening be safely exempt from surveillance: evidence from multicenter community-based cohorts

2024-9-6

AZD1775 synergizes with SLC7A11 inhibition to promote ferroptosis

2024-9-6

Advancing CRISPR base editing technology through innovative strategies and ideas

2024-9-2

The gut microbiome modulate response to immunotherapy in cancer

2024-9-2

An in-depth understanding of the role and mechanisms of T cells in immune organ aging and age-related diseases

2024-9-2

Zika virus infection induces glycometabolic disorder in northern pig-tailed macaques

2024-8-30

Multi-omics analysis reveals the genetic and environmental factors in shaping the gut resistome of a keystone rodent species

2024-8-30

Novel DNA methylation markers for early detection of gastric cardia adenocarcinoma and esophageal squamous cell carcinoma

2024-8-30

Profile of Dr. Songlin Chen

2024-8-29

Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2

2024-8-29

Inhibition of the RXRA-PPARα-FABP4 signaling pathway alleviates vascular cellular aging by an SGLT2 inhibitor in an atherosclerotic mice model

2024-8-29

Targeted genome duplications by amplification editing (AE)

2024-8-23

Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases

2024-8-22

Unveiling the evolutionary dynamics of microRNA-targeted plant laccase genes

2024-8-22

Nanowire-mediated miRNA delivery

2024-8-22

Shifts in reproductive strategies in the evolutionary trajectory of plant lineages

2024-8-22

Activation of the PGC-1α-mediated mitochondrial glutamine metabolism pathway attenuates female offspring osteoarthritis induced by prenatal excessive prednisone

2024-8-21

RpL38 modulates germ cell differentiation by controlling Bam expression in Drosophila testis

2024-8-21

New insights shed light on the enigma of genetic diversity and species complexity

2024-8-19

Optimizing ABA-based chemically induced proximity for enhanced intracellular transcriptional activation and modification response to ABA

2024-8-19

Crop antiviral defense: Past and future perspective

2024-8-15

Versatile plant genome engineering using anti-CRISPR-Cas12a systems

2024-8-15

Increase of PCSK9 expression in diabetes promotes VEGFR2 ubiquitination to inhibit endothelial function and skin wound healing

2024-8-15

Unlocking the potential: advancements and future horizons in ROR1-targeted cancer therapies

2024-8-12

Decoding the fish genome opens a new era in important trait research and molecular breeding in China

2024-8-12

Unveiling potential sex-determining genes and sex-specific markers in autotetraploid Carassius auratus

2024-8-9

Understanding the global cancer statistics 2022: growing cancer burden

2024-8-8

MSC-mediated mitochondrial transfer restores mitochondrial DNA and function in neural progenitor cells of Leber’s hereditary optic neuropathy

2024-8-8

Versatile and efficient mammalian genome editing with Type I-C CRISPR System of Desulfovibrio vulgaris

2024-8-7

Whole-genome sequencing identifies novel genes for autism in Chinese trios

2024-8-7

PCAF-mediated acetylation of METTL3 impairs mRNA translation efficiency in response to oxidative stress

2024-8-3

Gut microbiota and healthy longevity

2024-8-2

A CRISPR/RfxCas13d-mediated strategy for efficient RNA knockdown in mouse embryonic development

2024-8-2

RBM25 depletion suppresses the growth of colon cancer cells through regulating alternative splicing of MNK2

2024-8-2

A novel neuroprotective method against ischemic stroke by accelerating the drainage of brain interstitial fluid

2024-8-2

Profile of Dr. Xiao-Jun Huang

2024-7-29

COVID-19 vaccine updates for people under different conditions

2024-7-29

The single-cell transcriptomic landscape of the topological differences in mammalian auditory receptors

2024-7-29

6-Phosphogluconate dehydrogenase 2 bridges the OPP and shikimate pathways to enhance aromatic amino acid production in plants

2024-7-24

Approach from the laboratory to the field: New strategies in the control of mosquito-borne infectious diseases

2024-7-23

Current status and impact of the Young Scientist Foundation of the National Natural Science Foundation on Chinese young scholars in cardiovascular research

2024-7-23

Temperature regulates negative supercoils to modulate meiotic crossovers and chromosome organization

2024-7-23

Molecular mechanisms of DNA lesion and repair during antibody somatic hypermutation

2024-7-23

CRISPR-based genetic screens advance cancer immunology

2024-7-23

Single-cell omics: experimental workflow, data analyses and applications

2024-7-23

Smooth muscle cell-specific genetic targeting by Myh11-driven Cre(ER) knockin mice

2024-7-22

Single-cell immune landscape of measurable residual disease in acute myeloid leukemia

2024-7-19