CRL3 E3 ligase regulates glutamine and cystine metabolisms

2024-9-13

ER membrane remodeling by targeting RTN4 induces pyroptosis to facilitate antitumor immune.

2024-9-10

RADICAL: a rationally designed ion channel activated by ligand for chemogenetics.

2024-9-2

Lcn2 secreted by macrophages through NLRP3 signaling pathway induced severe pneumonia

2024-8-24

Molecular architecture of mammalian pyruvate dehydrogenase complex

2024-8-22

An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines

2024-8-21

Advances in Gene and Cellular Therapeutic Approaches for Huntington’s Disease

2024-8-9

Adenosine-to-Inosine RNA editing in cancer: molecular mechanisms and downstream targets

2024-8-8

Correction to: Macrophages suppress cardiac reprogramming of fibroblasts <i>in vivo</i> via IFN-mediated intercellular self-stimulating circuit

2024-8-7

Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens

2024-8-1

Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model

2024-7-27

Lentivirus-modified hematopoietic stem cell gene therapy for advanced symptomatic juvenile metachromatic leukodystrophy: A long-term follow-up pilot study

2024-6-25

PKM2, the “K+ sink” in the tumor interstitial fluid

2024-6-24

CRISPR-based screening pinpoints H2AZ1 as a driver of senescence in human mesenchymal stem cells

2024-6-19

A novel loop-structure-based bispecific CAR that targets CD19 and CD22 with enhanced therapeutic efficacy against B-cell malignances

2024-6-1

NudCL2 is required for cytokinesis by stabilizing RCC2 with Hsp90 at the midbody

2024-5-27

A third dose of inactivated vaccine augments the potency, breadth, and duration of anamnestic responses against SARS-CoV-2

2024-5-27

High-throughput single-microbe RNA sequencing reveals adaptive state heterogeneity and host-phage activity associations in human gut microbiome

2024-5-23

Integrative analysis of transcriptome, DNA methylome, and chromatin accessibility reveals candidate therapeutic targets in hypertrophic cardiomyopathy

2024-5-23

ARID1A IDR Targets EWS-FLI1 Condensates and Finetunes Chromatin Remodeling

2024-5-18

SMAD2/3-SMYD2 and developmental transcription factors cooperate with cell cycle inhibitors to guide tissue formation

2024-5-17

IL-24 promotes atopic dermatitis-like inflammation through driving MRSA-induced allergic responses

2024-5-16

Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy

2024-5-14

Alzheimer's disease: insights into pathology, molecular mechanisms, and therapy

2024-5-11

Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China

2024-5-10

p21/Zbtb18 repress the expression of cKit to regulate the self-renewal of hematopoietic stem cells

2024-5-9

Noncoding RNA <i>Terc-53</i> and hyaluronan receptor Hmmr regulate ageing in mice

2024-5-9

Whole-exome sequencing identifies <i>ECPAS</i> as a novel potentially pathogenic gene in multiple hereditary families with nonsyndromic orofacial cleft

2024-5-2

Dissecting caspase-2-mediated cell death: from intrinsic PIDDosome activation to chemical modulation

2024-4-27

Boundless love: a German Professor Uli Schwarz in China

2024-4-22

Gut dysbiosis impairs intestinal renewal and lipid absorption in Scarb2 deficiency-associated neurodegeneration

2024-4-18

Discovery of <i>CCDC188</i> gene as a novel genetic target for human acephalic spermatozoa syndrome

2024-4-15

Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15

2024-4-13

Skeletal stem cells in bone development, homeostasis, and disease

2024-4-6

Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging

2024-4-5

Macrophages suppress cardiac reprogramming of fibroblasts <i>in vivo</i> via IFN-mediated intercellular self-stimulating circuit

2024-3-26

Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins

2024-3-22

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

2024-3-21

Comprehensive transcriptional atlas of human adenomyosis deciphered by the integration of single-cell RNA-sequencing and spatial transcriptomics

2024-3-15

DNA methylation clocks for estimating biological age in Chinese cohorts

2024-3-14

CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A

2024-3-13

Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy

2024-3-5

Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion

2024-3-5

Microbiota enterotoxigenic <i>Bacteroides fragilis</i>-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1

2024-3-4

Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis

2024-3-2

Metabolic cell death in cancer: Ferroptosis, cuproptosis, disulfidptosis, and beyond

2024-3-1

Correction to: EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation

2024-2-23

Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues

2024-2-15

Exploring unconventional attributes of red blood cells and their potential applications in biomedicine

2024-1-25

Pan Shu: The Founding figure of modern Chinese psychology

2024-1-17