Biomarkers are physical, functional, or biochemical indicators of physiological or disease processes. These key indicators provide important information for determining disease prognosis, predicting treatment responses, adverse events, drug interactions, and assessing baseline risks. The surge of interest in biomarker research has driven the development of new predictive, diagnostic, and prognostic products in modern medical practice, with biomarkers playing an increasingly vital role in the discovery and development of new drugs. To fully realize the utility of biomarkers, we need to deepen our understanding of disease mechanisms and the interactions between these mechanisms, therapeutic interventions, and proposed biomarkers. However, as we attempt to systematically assess the advantages and disadvantages of biomarkers, we are entering a new and challenging field. "Biomarkers in Medicine" (ISSN 1752-0363) is a peer-reviewed, rapid publication journal that provides commentary and analysis on advancements in the medical field, helping us understand the potential and practical applications of biomarkers in medicine. This journal aims to translate research knowledge into clinical practice to enhance the effectiveness of healthcare. As the scientific principles and regulatory acceptance of biomarkers in medicine and drug development become more established, biomarkers provide a platform for all stakeholders to communicate and debate various issues related to their potential utility and applications. Each issue is rich in content, offering comprehensive coverage for researchers, including guest editorials, interviews, reviews, research articles, viewpoints, priority paper evaluations, thematic reports, case reports, conference reports, and company profiles. The review scope is divided into thematic sections based on areas of therapeutic utility, with some issues including thematic sections on specific topics. "Biomarkers in Medicine" provides a platform for all professionals interested in identifying biomarkers to comment and debate their roles and formalization and approval in modern medicine. The audience of this journal includes academic and industrial researchers, clinicians, pathologists, clinical chemists, and regulatory professionals.