Asian Journal of Biochemistry

Bamba Lassana

M’Boh Gervais Mél

Bahi Gnogbo Alexis

Séri Kipré Laurent

Beugre Grah Avit Maxwe

Djaman Allico Joseph

Bio-Tolerance Evaluation of Parkia biglobosa-Based Dietary Supplement a Plant Species from Ivorian Medicinal Flora

基于科特迪瓦药用植物的帕基亚大果豆树膳食补充剂的生物耐受性评估

Amjad Ali Khan

Mohammad A. Alzohairy

Hepatoprotective Effects of Camel Milk against CCl4-induced Hepatotoxicity in Rats

骆驼奶对四氯化碳诱导的大鼠肝毒性的保护作用

Effects of leaf extract of Spilanthes uliginosa (SW) on total protein, albumin, total and conjugated bilirubin levels in ethylene glycol exposed albino rats were studied.The animals were divided into 3 groups namely; A, B and C and groups A and B were subdivided into 2; A I , A 2 , B 1 and B 2 .All the groups and subgroups contained 6 albino rats each and were given water and food ad libitum.Groups A 1 and B 1 with A 2 and B 2 were treated with 1.85 mg kgG 1 and 3.70 mg kgG 1 of 90% ethylene glycol intraperitoneally once, respectively.Groups B 1 and B 2 were also given 1 mL of the plant extract, respectively by oral incubation for 21 consecutive days while group C received only the water and food.The average body weights of the treated groups decreased significantly at p<0.05 compared to control.The result showed no significant change at p<0.05 in total protein levels and significant decrease in albumin, total and direct bilirubin levels compare to control.The result obtained suggests toxicity of ethylene glycol and the ability of the plant extract to affect the levels of the analyzed parameters.

A.J. Uraku

N. Ezeani

C. Ezeali

F.U. Ali

C.A. Afiukwa

L.N. Ebenyi

Effects of Extract of Spilanthes uliginosa (SW) on Total Protein, Albumin, Total and Conjugated Bilirubin in Ethylene Glycol Exposed Albino Rats

斯皮兰蒂斯·乌利戈萨纳提取物对乙二醇暴露的白色大鼠总蛋白、白蛋白、总胆红素和结合胆红素的影响

Enzymatic maceration of Morinda fruits was conducted with the enzymes like pectinase and diastase at 0.030 g kgG 1 as the extraction of juice from the ripened fruits of Morinda citrifolia and Morinda pubescens are difficult due to its slimy pulp.Juice yields were increased greatly with enzymatic treatment (p<0.05),The amounts of flavonoid and polyphenols as well as clarity of the juices were greatly varied because of different enzyme treatment.Juice treated with pectinase and diastase showed better clarity and sugar content than the untreated juice (p<0.05).The relative viscosity of the juice were also decreased in clarified and fermented juice of both fruits.The mass spectra of fermented juice of M. citrifolia exhibits 14 important peaks out of which 4 peaks are having larger % area.FT-Raman spectroscopy and gas chromatography techniques used for the assessments of its potential amino acids and fatty acid composition.

Desai Nivas

D.K. Gaikwad

Chemical Characterization of Enzymatically Treated Morinda Juice

酶处理诺丽果汁的化学表征

This study was designed to investigate the antidiabetic property of Cinnamomum iners leaves which were used traditionally to combat diabetes.Firstly, the antidiabetic activity of petroleum ether, chloroform, methanol and water extract of C. iners leaves was evaluated.Next, the potential extract which was the methanol extract was fractionated to obtain ethyl acetate, n-butanol, chloroform and aqueous fraction.The active chloroform fraction was subjected to subfractionation process to obtain subfraction 1 (SF 1) and subfraction 2 (SF 2).Cinnamomum iners leaves active portion (methanol extract, chloroform fraction and subfraction 1) was standardized using cinnamic aldehyde.The antidiabetic activity of standardized C. iners leaves was assessed by using Intra-Peritoneal Glucose Tolerance Test (IPGTT).The antidiabetic mechanism of active portion of C. iners leaves were also determined by measuring glucose absorption from the intestine.This study showed significant glucose tolerance effect of active portion of C. iners leaf after repeated oral administration in STZ-induced diabetic rats.The antidiabetic mechanism of subfraction 1 and chloroform fraction of C. iners leaf is by inhibiting glucose absorption from intestine.

Fazlina Mustaffa

Zurina Hassan

Mohd Zaini Asmawi

Cinnamomum iners Leaves as an Alternative Therapy for Diabetes

钝叶樟叶作为糖尿病替代疗法

Kandji Pape Matar

Thioune Ndeye Mareme

Djite Moustapha

Barry Néné Oumou Kess

Sarr Abasse

Faye Abdou

Ndiaye Siny

Mbacke Mame Ndoumb&eac

Ndour El Malick

Gueye-Tall Fatou

Gueye Papa Madieye

Evaluation of the Lipid Profile and Atherogenic Risk in Hypothyroid Patients

甲状腺功能减退患者血脂谱及动脉粥样硬化风险的评估

Background and Objective: The binding of SARS-CoV-2 to ACE2 inhibits the action of the latter on the RAAS (Renin Angiotensin Aldosterone System), which could increase blood pressure and disturbances in the hydroelectrolyte balance.The objective of this study was to determine the electrolyte profile of patients with COVID-19.Materials and Methods: Within that framework, a 3-month retrospective analytical study of patients infected with SARS-CoV-2 was conducted, admitted at Dalal Jamm Hospital and Aristide Le Dantec Hospital.Data were collected from the laboratory records of the said hospitals and included age, sex, clinical information (symptoms, underlying diseases and clinical forms) and blood ionogram results (natraemia and kalaemia).Statistical analysis was performed using SPSS software.Results: About 745 patients were recruited.The mean age of the study population was 54.22±18.53with a sex ratio of 1.15.Ten percent of the population had a severe form.Hypertension was the most frequent comorbidity (14.53%) followed by diabetes (11.73%).The most frequent electrolyte disorders were hyponatremia (13.02%) and hyperkalemia (6.97%).They were more frequent in men, elderly subjects, those with a severe form of the disease and those with comorbidities.Conclusion: This data suggested a disturbance of the hydro electrolytic homeostasis in subjects infected by SARS-CoV-2.It appears to be associated with age, gender, disease severity and the presence of comorbidity.

F. Ciss&eacut

S. Thiam

A. Ndiaye

T. Lamkinsi

A. Samba

D. Doupa

N.F. Coly

I.Y. Soumah

F. Diedhiou

F. Diallo

A. Diatta

N.D. Sall

Electrolytic Disorders in Senegalese SARS-CoV-2 Infected Subjects

塞内加尔SARS-CoV-2感染者的电解质紊乱

Background and Objective: Type 2 Diabetes Mellitus (DM) is a chronic metabolic illness that is becoming more common across the world.As a result of this trend, it is rapidly becoming an epidemic in some countries around the world, with the number of people affected expected to double in the next decade due to an increase in the elderly population, adding to the already existing burden on healthcare providers, particularly in less developed countries.Type 2 Diabetes Mellitus (T2DM) accounts for around 90% of all diabetes cases.The present study aimed to investigate the biochemical profile of type 2 diabetes patients.Materials and Methods: Survey on diabetes prevalence and biochemical profiles like Blood Glucose, Serum Glutamic Pyruvic Transaminase (SGPT), Serum Glutamic-Oxaloacetic Transaminase (SGOT), serum bilirubin (total), serum bilirubin (direct), alkaline phosphatase, total serum cholesterol, High-Density Lipoprotein (HDL) and Low-Density Lipoprotein (LDL) of selected people was done.Results: From the survey, it was found that type 2 diabetes is more prevalent among the rural population.Male with age group 50-80 is more prone to diabetes.Conclusion: Diabetes patients had higher total cholesterol, triglycerides, low-density lipoprotein levels and lower levels of high-density lipoprotein than normal healthy controls.

Al-Sana Ahmed

G. Jayalakshm

K. Sundar

Survey on Biochemical Parameters of Type 2 Diabetic Patients in Faizabad, India

印度法扎巴德2型糖尿病患者生化参数调查

Isaac John Umaru

Maryam Usman Ahme

Bilyaminu Habibu

Imaranezor Kenneth

Philip Shadrach

Muhammad Zuhairah I

Protective Role of Solandra longiflora Flower Extracts on Streptozotocin Diabetes Induced Albino Rats

金杯花提取物对链脲佐菌素诱导的糖尿病白化大鼠的保护作用

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Asian Journal of Biochemistry

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Bio-Tolerance Evaluation of Parkia biglobosa-Based Dietary Supplement a Plant Species from Ivorian Medicinal Flora

Hepatoprotective Effects of Camel Milk against CCl4-induced Hepatotoxicity in Rats

Effects of Extract of Spilanthes uliginosa (SW) on Total Protein, Albumin, Total and Conjugated Bilirubin in Ethylene Glycol Exposed Albino Rats

Chemical Characterization of Enzymatically Treated Morinda Juice

Cinnamomum iners Leaves as an Alternative Therapy for Diabetes

Bio-Tolerance Evaluation of Parkia biglobosa-Based Dietary Supplement a Plant Species from Ivorian Medicinal Flora

Evaluation of the Lipid Profile and Atherogenic Risk in Hypothyroid Patients

Electrolytic Disorders in Senegalese SARS-CoV-2 Infected Subjects

Survey on Biochemical Parameters of Type 2 Diabetic Patients in Faizabad, India

Protective Role of Solandra longiflora Flower Extracts on Streptozotocin Diabetes Induced Albino Rats