BMC Nutrition

Gallstones are a common digestive disorder that threatens human health. Iron deficiency may be related to the formation of gallstones, but there is limited current epidemiological research. The objective of this study was to investigate the relationship between iron status and gallstones. The datasets from the National Health and Nutrition Examination Survey (NHANES) 2017–2020 were used in a cross-sectional investigation. Gallstones were determined by using the 2007–2010 NHANES questionnaire. Multivariate linear regression models were used to examine the association between serum iron, serum ferritin and iron intake with the risk for gallstones. Subgroup analysis based on gender, age, race, and diabetes were performed. Fitted smoothing curves were used to describe the linear relationship. The research involved 7847 participants aged 20 and above, among whom 845 were identified as having gallstones. Participants with higher serum iron levels tended to have a lower gallstones prevalence. A negative relationship between serum iron and gallstones prevalence was observed (OR = 0.979, 95% CI:0.965–0.992). The group with the highest serum iron tertile had a 23.7% lower risk of gallstones compared to the lowest tertile (OR = 0.763, 95% CI:0.628‒0.929). Gallstone prevalence was inversely correlated with iron intake in model 1. The negative association between serum iron and gallstones remained stable in stratifications, including gender, age, race, and diabetes. Elevated serum iron was associated with a decreased prevalence of gallstones. However, to confirm the impact of long-term iron metabolism on gallstone formation, additional prospective research is necessary.

Si-Hua Wen

Xin Tang

Tao Tang

Zheng-Rong Ye

Association between serum iron and gallstones in US adults: a cross-sectional study

美国成年人血清铁与胆结石之间的关联：一项横断面研究

Abstract Background Malnutrition is a significant concern reported in adult critically ill patients, yet there is no gold standard to assess nutritional status in this population. This study examines the association between nutritional status and clinical outcomes in intensive care unit (ICU) patients using nutritional risk assessment tools and aims to look for the best tool. Method In a single-center prospective cohort study among 165 patients, the predictive performance of high or low malnutrition risk assessed by Nutritional Risk Screening (NRS), Modified Nutrition Risk in Critically Ill (m-NUTRIC), Mini-Nutritional-Assessment Short-Form (MNA-SF), Controlling Nutritional status (CONUT), and Prognostic Nutritional Index (PNI) were evaluated and compared for mortality, organ failure, length of hospitalization, and mechanical ventilation (MV). Results Different assessment tools showed various nutritional statuses. m-NUTRIC and NRS-2002 were found to be associated more strongly relative to other tools with mortality (RR = 1.72; 95% CI, 1.42–2.08) and (RR = 1.37; 95% CI, 1.08–1.72), organ failure (RR = 1.69; 95% CI, 1.44–1.96) and (RR = 1.22; 95% CI, 0.99–1.48), MV (RR = 1.46; 95% CI, 1.27–1.65) and (RR = 1.21; 95% CI, 1.04–1.39) respectively. There was no correlation between malnutrition levels assessed by mentioned tools except for NRS-2002 and length of hospitalization. In predicting mortality or illness severity, the cut points were different for some tools like NUTRIC-score and all assessed outcomes (3.5), MNA-SF and mortality (6.5), CONUT with mortality, and MV (6.5). Conclusions A considerable proportion of patients admitted to the ICU are at high risk for malnutrition. Compared to other tools, m-NUTRIC and NRS-2002 proved superior in predicting clinical outcomes in critically ill patients. Other tools overestimated the risk of malnutrition in the ICU so couldn’t predict clinical outcomes correctly.

Omid Moradi Moghaddam

Masoumeh Hosseinzadeh Emam

Pardis Irandoost

Mahdi Hejazi

Zeinab Iraji

Leila Yazdanpanah

Seyedeh Farnaz Mirhosseini

Abolfazl Mollajan

Mohammad Niakan Lahiji

Relation between nutritional status on clinical outcomes of critically ill patients: emphasizing nutritional screening tools in a prospective cohort investigation

危重患者营养状况与临床结局的关系：一项前瞻性队列研究中营养筛查工具的强调

Patients with heart failure (HF) often experience iron deficiency. Intravenous iron supplementation has been widely used in clinical practice to facilitate the treatment of HF. However, the association between dietary iron intake and HF still needs to be elucidated. This study aimed to evaluate the impact of dietary iron intake on HF in American adults. The data were extracted from the National Health and Nutrition Examination Survey (NHANES) 2009-2018. Iron dietary intake data were obtained from two 24-h dietary recall interviews. We examined baseline data and HF prevalence in different quartile groups of dietary iron intake (Q1-Q4). Two logistic regression models were established to evaluate the impact of Q4 (highest iron consumption) on the risk of HF. The study included 20,853 American adults (age ≥ 20 years). The participants with the highest iron intake (Q4) had the lowest prevalence of HF (Q1: 3.25%, Q2: 2.18%, Q3: 1.92%, Q4: 1.72%; P < 0.001). After adjusting for possible confounding factors, the highest iron intake (Q4) was significantly associated with a reduced risk of HF compared with that of Q1 (odds ratio 0.58, 95% confidence interval 0.41-0.82; P = 0.003). This association remained stable in subgroups of women, current smokers, and Hispanics other than Mexican Americans. This study revealed that the dietary intake of iron was negatively associated with HF in adults without exceeding the tolerable maximum daily intake of 45 mg/day.

Yajie Wang

Jie Yang

Lei Yang

Liang Zheng

Association between dietary intake of iron and heart failure among American adults: data from NHANES 2009–2018

美国成年人饮食铁摄入与心力衰竭的关联：基于NHANES 2009-2018数据的研究

This pre-post intervention study aimed to assess the relationship between baseline dietary quality and the efficacy of a dietitian-guided weight reduction program, which has not been thoroughly documented to date.

Ying-Cheng Lin

Yen-Chien Chen

Yen-Ju Chen

Hui-Min Hsieh

Yun-Yu Chen

Wen-Hong Wang

Hui-Fen Lang

Yi-Jun Liao

Yen-Chun Peng

Teng-Yu Lee

Sheng-Shun Yang

Yu-Cheng Cheng

Shao-Ciao Luo

Han-Chung Lien

Impact of baseline dietary quality on the efficacy of a dietitian-guided weight reduction program

基线饮食质量对营养师指导的减重计划效果的影响

The economic crisis in Sri Lanka worsened food insecurity, with millions facing moderate-to-severe food shortages. This study evaluates the effectiveness of cash transfers combined with mobile health education in enhancing dietary diversity and food security among Sri Lankan households during the crisis.

Millawage Supun Dilara Wijesinghe

Upeksha Gayani Karawita

Nissanka Achchi Kankanamalage Ayoma Iroshanee Nissanka

Balangoda Muhamdiramlage Indika Gunawardana

Weerasinghe Mudiyanselage Prasad Chathuranga Weerasinghe

Yakupitiyage Asanka Supun

Dilka Rashmi Peiris

Roshan Dela Bandara

Ranjith Batuwanthudawe

Improving dietary diversity and food security among low-income families during financial crisis using cash transfers and mHealth: experience from two selected districts in Sri Lanka

通过现金转移和移动健康改善低收入家庭在金融危机期间的饮食多样性和粮食安全：来自斯里兰卡两个选定地区的经验

Maternal nutrition is a key factor influencing birth and offspring health outcomes in later life. Dietary diversity (DD) is a proxy for the macro/micronutrient adequacy of an individual's diet. There is inadequate comprehensive evidence regarding maternal nutrition during pregnancy, measured through DD and birth outcomes. This study aimed to provide extensive evidence on maternal DD during pregnancy and birth outcomes.

Amare Abera Tareke

Edom Getnet Melak

Bezawit Ketsela Mengistu

Jafar Hussen

Asressie Molla

Association between maternal dietary diversity during pregnancy and birth outcomes: evidence from a systematic review and meta-analysis

孕产妇孕期饮食多样性与出生结局的关联：基于系统综述和Meta分析的证据

Medically tailored meal (MTM) programs provide home-delivered meals to people living with serious illness and poor nutritional status. Client outcome studies have found evidence of decreased healthcare utilization and cost savings associated with MTM program participation, and inconclusive evidence of change in health measures. The purpose of this study was to use a novel observational framework to describe the client profile and change in health outcomes using routinely collected health and program data from a community-based MTM program at MANNA (Philadelphia, PA). Clients reported their self-rated health and experiences of food insecurity and malnutrition. Healthcare providers reported clients' body mass index, systolic blood pressure, and hemoglobin A1C. These health outcomes, measured at program intake and 3–6 months later, were linked with administrative data for 1,959 clients who completed at least two months of MTM services in 2020, 2021, and 2022. Clients exhibited substantial heterogeneity in demographics and health status at intake. Self-reported malnutrition risk decreased significantly over program duration (p < .001). Nearly one-third of clients with poor health reported improvement over time. Over 60% of clients with obesity experienced stable BMI. Clients with hypertension experienced significant improvements in systolic blood pressure (p < .001). Clients with diabetes and available data (n = 45) demonstrated significant reduction in hemoglobin A1C (p = .005). We found evidence that participation in MANNA's MTM program was associated with favorable health outcomes for clients with serious illness and nutritional risk. Community-based organizations can maximize the completeness of their data by focusing on routinely collected internal data like validated health screeners and surveys.

Jessica M. Sautter

Jule Anne Henstenburg

Adrian Glass Crafford

Ian Rowe-Nicholls

Victor S. Diaz

Kaitlyn Ann Bartholomew

Julia S. Evans

Maria R. Johnson

Jeffrey Zhou

Deeksha Ajeya

Health outcomes reported by healthcare providers and clients of a community-based medically tailored meal program

社区定制膳食计划中医疗服务提供者和客户报告的健康结果

acBWQ6	BMC Nutr.
Journal Impact	1.78
mbqgSu	NUTRITION & DIETETICS(Q3)

ISSN	2055-0928
h-index	31

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JrpmBe	网友分享经验：15 Weeks

BMC Nutrition

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Association between serum iron and gallstones in US adults: a cross-sectional study

Relation between nutritional status on clinical outcomes of critically ill patients: emphasizing nutritional screening tools in a prospective cohort investigation

Association between dietary intake of iron and heart failure among American adults: data from NHANES 2009–2018

Impact of baseline dietary quality on the efficacy of a dietitian-guided weight reduction program

Improving dietary diversity and food security among low-income families during financial crisis using cash transfers and mHealth: experience from two selected districts in Sri Lanka

Association between maternal dietary diversity during pregnancy and birth outcomes: evidence from a systematic review and meta-analysis

Improving dietary diversity and food security among low-income families during financial crisis using cash transfers and mHealth: experience from two selected districts in Sri Lanka

Impact of baseline dietary quality on the efficacy of a dietitian-guided weight reduction program

Association between dietary intake of iron and heart failure among American adults: data from NHANES 2009–2018

Health outcomes reported by healthcare providers and clients of a community-based medically tailored meal program