Optimal performance objectives in the highly conserved bone morphogenetic protein signaling pathway

2024-9-14

Tipping-point transition from transient to persistent inflammation in pancreatic islets

2024-9-12

EpiScan: accurate high-throughput mapping of antibody-specific epitopes using sequence information

2024-9-9

Codon usage and expression-based features significantly improve prediction of CRISPR efficiency

2024-9-3

A Boolean model explains phenotypic plasticity changes underlying hepatic cancer stem cells emergence

2024-9-2

Network topology and interaction logic determine states it supports

2024-8-28

Recovering biomolecular network dynamics from single-cell omics data requires three time points

2024-8-27

Constraint-based modelling predicts metabolic signatures of low and high-grade serous ovarian cancer

2024-8-24

SignalingProfiler 2.0 a network-based approach to bridge multi-omics data to phenotypic hallmarks

2024-8-23

Assessing structural uncertainty of biochemical regulatory networks in metabolic pathways under varying data quality

2024-8-22

Integrated-omics analysis with explainable deep networks on pathobiology of infant bronchiolitis

2024-8-22

Using DeepSignalingFlow to mine signaling flows interpreting mechanism of synergy of cocktails

2024-8-21

Spatial computational modelling illuminates the role of the tumour microenvironment for treating glioblastoma with immunotherapies

2024-8-18

Insights gained from computational modeling of YAP/TAZ signaling for cellular mechanotransduction

2024-8-15

Practical parameter identifiability and handling of censored data with Bayesian inference in mathematical tumour models

2024-8-14

Hybridizing mechanistic modeling and deep learning for personalized survival prediction after immune checkpoint inhibitor immunotherapy

2024-8-14

A practically efficient algorithm for identifying critical control proteins in directed probabilistic biological networks

2024-8-12

Transient frequency preference responses in cell signaling systems

2024-8-11

High-affinity biomolecular interactions are modulated by low-affinity binders

2024-8-10

Author Correction: Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

2024-8-8

Modelling HIV-1 control and remission

2024-8-8

On the salient limitations of the methods of assembly theory and their classification of molecular biosignatures

2024-8-7

Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data

2024-8-2

Bifurcations in coupled amyloid-β aggregation-inflammation systems

2024-7-30

A possible path to persistent re-entry waves at the outlet of the left pulmonary vein

2024-7-23

Self-consistent signal transduction analysis for modeling context-specific signaling cascades and perturbations

2024-7-19

Including glutamine in a resource allocation model of energy metabolism in cancer and yeast cells

2024-7-18

A deep position-encoding model for predicting olfactory perception from molecular structures and electrostatics

2024-7-17

Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation

2024-7-16

Cancer mutationscape: revealing the link between modular restructuring and intervention efficacy among mutations

2024-7-13

Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling

2024-7-12

Computational gastronomy: capturing culinary creativity by making food computable

2024-7-8

A comprehensive review of computational cell cycle models in guiding cancer treatment strategies

2024-7-5

Revisiting the evolution of bow-tie architecture in signaling networks

2024-6-29

Longitudinal single-cell data informs deterministic modelling of inflammatory bowel disease

2024-6-24

Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

2024-6-21

Canalization reduces the nonlinearity of regulation in biological networks

2024-6-13

interFLOW: maximum flow framework for the identification of factors mediating the signaling convergence of multiple receptors

2024-6-10

Low-frequency ERK and Akt activity dynamics are predictive of stochastic cell division events

2024-6-4

Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways

2024-6-3

Integrated omics of Saccharomyces cerevisiae CENPK2-1C reveals pleiotropic drug resistance and lipidomic adaptations to cannabidiol

2024-5-31

Identification of drug responsive enhancers by predicting chromatin accessibility change from perturbed gene expression profiles

2024-5-30

The art of modeling gene regulatory circuits

2024-5-29

Inferring upstream regulatory genes of FOXP3 in human regulatory T cells from time-series transcriptomic data

2024-5-29

Mechanisms of cell size regulation in slow-growing Escherichia coli cells: discriminating models beyond the adder

2024-5-29

Flexible modeling of regulatory networks improves transcription factor activity estimation

2024-5-28

Extending PROXIMAL to predict degradation pathways of phenolic compounds in the human gut microbiota

2024-5-27

Enhancing mass spectrometry imaging accessibility using convolutional autoencoders for deriving hypoxia-associated peptides from tumors

2024-5-27

A negative feedback loop underlies the Warburg effect

2024-5-24

Comparative analysis of metabolic models of microbial communities reconstructed from automated tools and consensus approaches

2024-5-23