Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome

2024-9-6

Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects

2024-9-5

Targeting Fascin1 maintains chondrocytes phenotype and attenuates osteoarthritis development

2024-9-4

Bone targeted nano-drug and nano-delivery

2024-9-4

Osteoclasts control endochondral ossification via regulating acetyl-CoA availability

2024-8-28

The HOXC10/NOD1/ERK axis drives osteolytic bone metastasis of pan-KRAS-mutant lung cancer

2024-8-27

SREBP2 restricts osteoclast differentiation and activity by regulating IRF7 and limits inflammatory bone erosion

2024-8-27

Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in the OIM model of osteogenesis imperfecta

2024-8-26

Rejuvenation of BMSCs senescence by pharmacological enhancement of TFEB-mediated autophagy alleviates aged-related bone loss and extends lifespan in middle aged mice

2024-8-21

Coactivator-independent vitamin D receptor signaling causes severe rickets in mice, that is not prevented by a diet high in calcium, phosphate, and lactose

2024-8-20

Induction of osteoblast apoptosis stimulates macrophage efferocytosis and paradoxical bone formation

2024-8-5

Ageing-related bone and immunity changes: insights into the complex interplay between the skeleton and the immune system

2024-8-5

PDZK1 protects against mechanical overload-induced chondrocyte senescence and osteoarthritis by targeting mitochondrial function

2024-7-17

Caspase-8 promotes scramblase-mediated phosphatidylserine exposure and fusion of osteoclast precursors

2024-7-11

Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease

2024-7-10

PCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging

2024-7-4

Retraction Note: Circular RNA circStag1 promotes bone regeneration by interacting with HuR

2024-6-24

FGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development

2024-6-24

Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor

2024-6-7

Lumbar instability remodels cartilage endplate to induce intervertebral disc degeneration by recruiting osteoclasts via Hippo-CCL3 signaling

2024-5-30

ATP6AP2, a regulator of LRP6/β-catenin protein trafficking, promotes Wnt/β-catenin signaling and bone formation in a cell type dependent manner

2024-5-29

Matrix stiffening promotes chondrocyte senescence and the osteoarthritis development through downregulating HDAC3

2024-5-24

Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis

2024-5-23

Author Correction: FAR591 promotes the pathogenesis and progression of SONFH by regulating Fos expression to mediate the apoptosis of bone microvascular endothelial cells

2024-5-20

RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts

2024-5-15

Prospects and challenges for the application of tissue engineering technologies in the treatment of bone infections

2024-5-14

Multi-omics analysis of human tendon adhesion reveals that ACKR1-regulated macrophage migration is involved in regeneration

2024-5-7

Pannexins in the musculoskeletal system: new targets for development and disease progression

2024-5-6

Author Correction: Insights and implications of sexual dimorphism in osteoporosis

2024-4-15

Sorafenib inhibits ossification of the posterior longitudinal ligament by blocking LOXL2-mediated vascularization

2024-4-10

Cell membrane vesicles derived from hBMSCs and hUVECs enhance bone regeneration

2024-4-9

Skeletal interoception in osteoarthritis

2024-4-1

The pathogenic mechanism of syndactyly type V identified in a Hoxd13Q50R knock-in mice

2024-4-1

Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx

2024-3-29

Kdm6a-CNN1 axis orchestrates epigenetic control of trauma-induced spinal cord microvascular endothelial cell senescence to balance neuroinflammation for improved neurological repair

2024-3-25

β-Receptor blocker enhances the anabolic effect of PTH after osteoporotic fracture

2024-3-21

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

2024-3-12

Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and pain

2024-3-5

Targeted knockdown of PGAM5 in synovial macrophages efficiently alleviates osteoarthritis

2024-3-4

A DNA tetrahedron-based ferroptosis-suppressing nanoparticle: superior delivery of curcumin and alleviation of diabetic osteoporosis

2024-2-29

Aging impairs the osteocytic regulation of collagen integrity and bone quality

2024-2-26

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development

2024-2-23

Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles

2024-2-22

Author Correction: Ammonia promotes the proliferation of bone marrow-derived mesenchymal stem cells by regulating the Akt/mTOR/S6k pathway

2024-2-20

RANKL inhibition reduces lesional cellularity and Gαs variant expression and enables osteogenic maturation in fibrous dysplasia

2024-2-20

Insights and implications of sexual dimorphism in osteoporosis

2024-2-18

Spatial analysis of the osteoarthritis microenvironment: techniques, insights, and applications

2024-2-4

Age-related secretion of grancalcin by macrophages induces skeletal stem/progenitor cell senescence during fracture healing

2024-1-25

Transcriptional reprogramming during human osteoclast differentiation identifies regulators of osteoclast activity

2024-1-24

The role and applications of extracellular vesicles in osteoporosis

2024-1-23