Biomedical and Biopharmaceutical Research

40-year-old woman, unemployed. She sought Nutrition Consultation for nutritional control, as she was taking oral anticoagulant therapy. No other pathologies requiring nutritional therapy, but she wanted to lose a little weight. She is followed in the Thrombophilia Consultation for Antiphospholipid Syndrome (APS) for mutation of the prothrombin gene in heterozygosity. She takes warfarin as an oral anticoagulant, with INR (International Normalized Ratio) control. Keywords: International Normalized Ratio, nutritional intervention, vitamin K, Antiphospholipid Syndrome, warfarin

Bruno Sousa

Antiphospholipid Syndrome (Clinical case)

抗磷脂综合征（临床病例）

Luis Monteiro Rodrigues

This issue in brief (Editorial)

本期简述（社论）

A new development cycle to begin (Editorial)

新发展周期即将开启（社论）

SCIENCE AND TECHNOLOGY, PATHS TO INDEPENDENCE In this annual meeting of FESBE, we will celebrate its 36th edition. In particular, we will have together the 57th annual meeting of the Brazilian Society of Physiology (SBFis - Founding Society of FESBE) and the 1st annual meeting of the recently created DOHaD Society (Developmental Origins of Health and Disease), the most recently affiliated to FESBE. It will certainly be one of the main scientific meetings in the country in 2022. CIÊNCIA E TECNOLOGIA, CAMINHOS PARA A INDEPENDÊNCIA Neste encontro anual da FESBE comemoraremos sua XXXVI edição. Em especial teremos em conjunto a LVII reunião anual da Sociedade Brasileira de Fisiologia (SBFis - Sociedade Fundadora da FESBE) e a I reunião anual da recém-criada Sociedade DOHaD (Origens Desenvolvimentistas da Saúde e da Doença), a mais recém afiliada à FESBE. Certamente será um dos principais encontros científicos no país neste ano de 2022.

Eduardo Colombari

XXXVI Annual Meeting of Federation of Societies of Experimental Biology (FeSBE) Abstracts

第XXXVI届实验生物学学会联合会年会摘要

The effect of collagen peptides on various aspects of skin and hair physiology is known but needs further studies. Thus, the objective of this study was to evaluate the clinical changes in skin and hair after 90 days of treatment with oral supplementation of 5 g/day of collagen peptides. For this, 60 healthy female participants were enrolled, aged 45 to 60 years old, with the primary objective of evaluating the effect of the ingestion of a bioactive collagen peptides-based supplementation in the cutaneous microrelief, reduction of wrinkles, thickness, and echogenicity of the dermis, as well as in the mechanical properties of the hair using biophysical and skin imaging techniques. The present study showed important benefits in relevant skin visual parameters, dermis density, and hair strength with the obtained data. In addition, considering that the aging process affects the hair's mechanical resistance due to hair fiber thinner, the proposed treatment was effective for aged hair. In conclusion, the collagen peptides oral supplementation is essential not only for improving skin conditions but also for hair care once it significantly increases the mechanical hair resistance evaluated by objective measurements. Keywords: Collagen peptides, skin aging, skin imaging techniques, hair mechanical properties, clinical study

Patricia M. B. G. Maia Campos

Maísa Oliveira de Melo

Marina Mendes Fossa Shirata

Marcella Gabarra Leite

Oral intake of Bioactive Collagen Peptides in the improvement of skin and hair: clinical studies by instrumental measurements

口服生物活性胶原蛋白肽在改善皮肤和头发中的作用：基于仪器测量的临床研究

Community and hospital pharmacists are responsible for the correct dispensation of antibiotics and patient counselling. This descriptive study aimed to identify the potentially effective pharmacists’ interventions which improved patients’ antibiotic adherence, based on the findings of a set of studies identified in a previous developed systematic review. Only controlled trials evaluating the impact of pharmaceutical interventions on patient adherence to antibiotics, i.e., intervention group vs. usual care/control group were conveniently selected. These studies were grouped and analyzed based on the distinction between trials with significant vs. non-significant improvements on patients’ adherence to antibiotics. Twenty-one trials were identified, but only 2/3 presented statistically significant results. Diverse pharmaceutical interventions significantly improved patients’ antibiotic adherence, such as structured interventions, the use of visual aids, detailed counseling, written information, call-back phone calls, or the dispensation of personalized doses of antibiotics. Reinforced pharmacist education is likely to be especially relevant in the case of complex therapies (e.g., H. pylori treatment) and/or low literacy patients. In conclusion, structured and/or reinforced pharmaceutical interventions can significantly improve patients’ antibiotic adherence in community or hospital pharmacies, according to some of the analyzed studies.

Carla Pires

Improvement of patients’ antibiotic adherence: a descriptive analysis of pharmacists’ interventions

患者抗生素依从性改善：药师干预的描述性分析

Catarina Rosado

Luís Monteiro Rodrigues

Bernardo Palma

Miguel Remondes

Marina Badenes

Ângela Afonso

Constantinos Athanassopoulos

Catarina Leite

Cíntia Pêgo

Vera Isca

Ana Júlio

Margarida Florindo

Ana Ribeiro

2023 CBIOS Scientific Seminars - Book of Abstracts

2023 CBIOS科学研讨会 - 摘要集

The Neocarya macrophylla plant is used traditionally for food, medicinal, spiritual and industrial purposes. It is also used as a soap, dye, glue, fodder, termite repellent, firewood and for structural materials. Few studies on the physicochemical, nutritional content, phytochemical and pharmacological activities have validated the benefits of N. macrophylla to humanity as a food, in cosmetics or pharmaceutical products. The major bioactive constituents identified in the plant so far are steroids and flavonoids, such as, stigmasterol, quercetin, catechin and its related glycosides, as well as glucosamines. Extracts of the plant have shown good antivenom, antimicrobial, analgesic, anti-inflammatory, antimycobacterial, anthelmintic and antioxidant activities. Acute toxicity studies have confirmed the plant to be toxic. More studies on the plant are required in order to exploit other biological activities as claimed by traditional healers and also to isolate more bioactive compounds. In addition, the safety and tolerability assessment of N. macrophylla should be undertaken due to its widespread usage.

Amina Yusuf Jega

Musa Ismail Abdullahi

Abubakar Alhaji Muhammad

Kasimu Ghandi Ibrahim

Hajara Adamu Wasagu

Florencia Z. Brauning

Gabrielle Bangay

Patricia Rijo

Neocarya macrophylla (Chrysobalanaceae): Review of taxonomy, ethnobotany, phytochemistry and biological activities

大叶新木姜子（樟科）：分类学、民族植物学、植物化学及生物活性综述

Eyelash extensions have gained popularity as a non-invasive cosmetic procedure, aiming to enhance the length and thickness of natural eyelashes. Despite their widespread use, scientific exploration into the methods, safety considerations, and aesthetic implications of eyelash extensions remains limited. This study conducts a comprehensive literature review to analyze the current state of scientific literature on the eyelash extension industry, identifying gaps for future research. In this study, there is an emphasis on the importance of adhesive properties, drying time, and safety considerations in the evolution of eyelash extension materials. Safety concerns associated with eyelash extensions side effects exist and legislation for adequate professional training and hygiene standards is needed. Aesthetic considerations delve into cultural and personal preferences, exploring the relationship between lash aesthetics, self-esteem, body image, and social perceptions. In conclusion, as eyelash extensions continue to be a prevalent trend worldwide, there is a necessity for extensive research to inform professionals and clients about potential risks and benefits. Further investigations in safety standards, application techniques, and aesthetic implications will contribute to the advancement of beauty science and the informed decision-making of individuals seeking eyelash enhancements, making the procedure safer and even more popular.

A Review on Eyelash Extensions: Methods, Safety, and Aesthetic Considerations

睫毛延长术综述：方法、安全性及美学考量

Telerehabilitation offers a transformative approach to physiotherapy, offering convenience, practicality, and sustainability. This paper presents a clinical study conducted at Unidade Local de Saúde do Oeste, in Portugal, involving 37 physiotherapy patients with chronic shoulder pain who utilized the Clynx® Platform for an average of 15.22 home-based sessions. Analysis of physiotherapist login data and patient travel data allowed for evaluation of platform usability, physiotherapist time management, and environmental impact. Patients highlighted schedule flexibility and time optimization as primary advantages, with 36.85% of sessions occurring on weekends and after hours, catering especially to busy professionals. In this study, telerehabilitation saved over 12,000 kilometres of travel and related expenses, while reducing carbon emissions by over 1.30 tons. The Clynx® Platform optimized physiotherapist-patient time management, saving approximately 45.30% of time in mild patient care, which could be redirected to more acute cases, potentially alleviating waiting lists in public hospitals. Telerehabilitation demonstrated positive impacts on usability, socioeconomic factors, and environmental indicators for both patients and healthcare professionals, driving the digitization of physiotherapy towards efficient, sustainable, and patientcentric care. This study underscores telerehabilitation as a promising avenue for the future of physiotherapy.

Irina Esteves Lopes

Maria Leonor Adrião

Paulo Clemente

Hugo Plácido da Silva

Gil Dias

Gonçalo Chambel

Joana Figueiredo Pinto

Exploring Telerehabilitation with Clynx® Platform: Usability and Impact Assessment

探索Clynx®平台远程康复：可用性与影响评估

涉及主题	医学生物化学内科学遗传学病理生物化学物理有机化学
出版信息	出版商: ALIES，出版周期: ，期刊类型: journal，开源期刊: 否
基本数据	创刊年份: 2019，原创研究文献占比: 0.00%，自引率:N.A.， Gold OA占比: 0.00%
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