BHLHE41, a transcriptional repressor involved in physiological processes and tumor development

2024-9-10

Targeting tumor associated macrophages (TAMs) reprograms tumor immune microenvironment to promote solid tumor immunotherapy

2024-9-5

Correction to: EMP2 induces cytostasis and apoptosis via the TGFβ/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma

2024-9-3

TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation

2024-9-2

PSMD2 overexpression as a biomarker for resistance and prognosis in renal cell carcinoma treated with immune checkpoint and tyrosine kinase inhibitors

2024-9-2

Telomere transcripts act as tumor suppressor and are associated with favorable prognosis in colorectal cancer with low proliferating cell nuclear antigen expression

2024-9-2

Next-generation BCMA-targeted chimeric antigen receptor CARTemis-1: the impact of manufacturing procedure on CAR T-cell features

2024-8-27

Pre-existing cell subpopulations in primary prostate cancer tumors display surface fingerprints of docetaxel-resistant cells

2024-8-20

Characterization and proteomic analysis of plasma-derived small extracellular vesicles in locally advanced rectal cancer patients

2024-8-20

Single-cell RNA transcriptomic analyses of tumor microenvironment of ovarian metastasis in gastric cancer

2024-8-20

Optimizing the spatial immune landscape of CD103+CD8+ tissue-resident memory T cells in non-small cell lung cancer by neoadjuvant chemotherapy

2024-8-19

Interferon Gamma Inducible Protein 30: from biological functions to potential therapeutic target in cancers

2024-8-14

Loss of histone deubiquitinase Bap1 triggers anti-tumor immunity

2024-8-14

ZNF468-mediated epigenetic upregulation of VEGF-C facilitates lymphangiogenesis and lymphatic metastasis in ESCC via PI3K/Akt and ERK1/2 signaling pathways

2024-8-14

Tertiary lymphoid structures and their therapeutic implications in cancer

2024-8-12

Disrupting YAP1-mediated glutamine metabolism induces synthetic lethality alongside ODC1 inhibition in osteosarcoma

2024-8-8

Marine derived macrolide bryostatin 4 inhibits the TGF-β signaling pathway against acute erythroleukemia

2024-7-31

COLEC10 inhibits the stemness of hepatocellular carcinoma by suppressing the activity of β-catenin signaling

2024-7-30

Acidity and hypoxia of tumor microenvironment, a positive interplay in extracellular vesicle release by tumor cells

2024-7-18

Panoramic tumor microenvironment in pancreatic ductal adenocarcinoma

2024-7-15

A dual-targeting approach with anti-IL10R CAR-T cells engineered to release anti-CD33 bispecific antibody in enhancing killing effect on acute myeloid leukemia cells

2024-7-15

Fasting in combination with the cocktail Sorafenib:Metformin blunts cellular plasticity and promotes liver cancer cell death via poly-metabolic exhaustion

2024-7-11

Comprehensive multiomics analysis of the signatures of gastric mucosal bacteria and plasma metabolites across different stomach microhabitats in the development of gastric cancer

2024-7-4

Suppressing SENP1 inhibits esophageal squamous carcinoma cell growth via SIRT6 SUMOylation

2024-7-2

Deciphering the molecular landscape: evolutionary progression from gynecomastia to aggressive male breast cancer

2024-6-18

The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism

2024-6-18

IRE1α inhibitor enhances paclitaxel sensitivity of triple-negative breast cancer cells

2024-6-18

Antitumor activity of afatinib in EGFR T790M-negative human oral cancer therapeutically targets mTOR/Mcl-1 signaling axis

2024-6-18

ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity

2024-5-31

HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function

2024-5-29

OrganoIDNet: a deep learning tool for identification of therapeutic effects in PDAC organoid-PBMC co-cultures from time-resolved imaging data

2024-5-28

A systematic review on the culture methods and applications of 3D tumoroids for cancer research and personalized medicine

2024-5-28

Deciphering fatty acid biosynthesis-driven molecular subtypes in pancreatic ductal adenocarcinoma with prognostic insights

2024-5-16

Targeted gene delivery systems for T-cell engineering

2024-5-16

SPG21, a potential oncogene targeted by miR-128-3p, amplifies HBx-induced carcinogenesis and chemoresistance via activation of TRPM7-mediated JNK pathway in hepatocellular carcinoma

2024-5-16

Research advances in the molecular classification of gastric cancer

2024-5-8

Correction to: 3D bioprinted tumor model: a prompt and convenient platform for overcoming immunotherapy resistance by recapitulating the tumor microenvironment

2024-4-30

Targeting Dectin-1 and or VISTA enhances anti-tumor immunity in melanoma but not colorectal cancer model

2024-4-26

Rituximab potentially improves clinical outcomes of CAR-T therapy for r/r B-ALL via sensitizing leukemia cells to CAR-T-mediated cytotoxicity and reducing CAR-T exhaustion

2024-4-25

LILRB2 promotes immune escape in breast cancer cells via enhanced HLA-A degradation

2024-4-24

Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis

2024-4-23

Chordoma cells possess bone-dissolving activity at the bone invasion front

2024-4-23

Correction to: Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling

2024-4-16

The emerging role of CARM1 in cancer

2024-4-15

Establishment, characterization, and biobanking of 36 pancreatic cancer organoids: prediction of metastasis in resectable pancreatic cancer

2024-4-15

Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals immune suppression subtypes and establishes a novel signature for determining the prognosis in lung adenocarcinoma

2024-4-15

Downregulation of GPX8 in hepatocellular carcinoma: impact on tumor stemness and migration

2024-4-12

Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling

2024-4-9

Hedgehog ligand and receptor cooperatively regulate EGFR stability and activity in non-small cell lung cancer

2024-4-3

Efficacy of programmed cell death 1 inhibitor maintenance after chimeric antigen receptor T cells in patients with relapsed/refractory B-cell non-Hodgkin-lymphoma

2024-4-2