Journal of Biologically Active Products from Nature

Francis Chukwumma Omeonu

Michael Oluwambe Taiwo

Oyeniyi Stephen Bejide

Adebanke Adebimpe Adetayo

Blessing Adebola Oyedeji

Anti-ulcer potential of edible mushroom ( Pleurotus pulmo-narius ) on indomethacin-induced gastric ulcer in male wistar rats

食用蘑菇（Pleurotus pulmo-narius）对雄性Wistar大鼠吲哚美辛诱导的胃溃疡的抗溃疡潜力

Ishita Guleria

Amita Kumari

Marie-Aleth Lacaille-Dubois

Vikas Kumar

Chirag N. Patel

Prasanth Kumar Sivakumar

Uma Ranjan Lal

Swati Pundir

Adesh K. Saini

Naseem A. Gaur

Sonam Kumari

Ashwani Kumar

Bioactive flavonoids from Populus ciliata : In vitro and In silico evaluation of antimicrobial, antioxidant and anti-inflammatory activities

来自Populus ciliata的生物活性黄酮类化合物：抗菌、抗氧化和抗炎活性的体外和计算机模拟评估

Rupinder Kaur

Ramandeep Kaur

Ravinder Singh

Urvashi Bhardwaj

Parul Sharma

Isolation and derivatization of bioactive compounds from Saussurea lappa roots with antifungal efficacy against plant pathogenic fungi

从Saussurea lappa根中分离和衍生化具有抗植物病原真菌活性的生物活性化合物

Affaf Laassami

Hayet Chelghoum

Farid Chebrouk

Farah Chemame

Hanane Boutebal

Noureddine Bouras

Mohamed Aboumustapha

Moufida Hamidi

Chemical composition and antimicrobial properties of Cymbopogon citratus essential oils against reference strains and pathogens isolated from vaginal and urinary samples

柠檬香茅精油的化学成分及其对阴道和尿液样本中分离的参考菌株和病原体的抗菌特性

Robert Christopher

Ethnobotanical uses, biological activities and phytochemistry of mangrove plant species: A review

红树林植物物种的民族植物学用途、生物活性和植物化学成分：综述

AbstractThe present study aimed to investigate the fatty acid composition and in vitro anticancer activities of the flower and leaf extracts of Sesbania grandiflora against breast cancer cells. Fatty acids (FA) were isolated using the method of Harvey's 1994 and profiled using gas chromatography-mass spectrometry (GC-MS). GC-MS analysis identified fourteen FAs in the flower extract and nine FAs in the leaf extract. Palmitic acid (5629.85 μg g−1) and ω-6 linolenic acid (12447.73 μg g−1) are the most abundant in the flower extract, while ω-6 linolenic acid (202576.9 μg g−1) is predominant in the leaf extract. The anticancer potential of the extracts was evaluated against the MCF-7 human breast cancer cell line through in-vitro analysis. The MTT assay results showed that the flower FA fraction most effectively inhibited the growth of MCF-7 cells, with an IC50 value of 47.73 μg/mL. Treatment with leaf and flower extracts induced typical apoptotic morphology in MCF-7 cells. Dual acridine orange/ethidium bromide (AO/EB) fluorescent staining revealed treated cells undergoing early and late stages of apoptosis. Both FA extracts, particularly flower FA extract, demonstrated strong anticancer potential, suggesting their efficacy as anticancer agents. This is the first-ever report on the anticancer efficacy of FA extracts from S. grandiflora, tested on MCF-7 breast cancer cells through various cellular assays, including cell viability and apoptosis assays. These findings provide mechanistic insight into the anticancer activities of FA extracts against MCF-7 cells and support their potential use in breast cancer treatment.GRAPHICAL ABSTRACTDisplay full size

Deepthi Kalanandan

Gopika Sivan

Renjith Pootharoth Kunhikattil

Habeeb Rahman Keedakkadan

Ajeeshkumar Kizhakkeppurath Kumaran

Chandramohanakumar Narayanan Nair

Fatty acid fractions from Sesbania grandiflora induce apoptosis in MCF-7 human breast cancer cells: A promising anticancer strategy

来自Sesbania grandiflora的脂肪酸组分诱导MCF-7人乳腺癌细胞凋亡：一种有前景的抗癌策略

Abbreviation	J. Biol. Act. Prod. Nat.
Journal Impact	0.88
Quartiles(Global)	CHEMISTRY, MEDICINAL(Q4)

ISSN	2231-1866, 2231-1874
h-index	18

Publication Information	Publisher: Taylor and Francis Ltd.，Publishing cycle: ，Journal Type: journal，Open Access Journals: No
Basic data	Year of publication: 2011，Proportion of original research papers: 0.00%，Self Citation Rate:11.10%， Gold OA Rate: 0.00%

Journal of Biologically Active Products from Nature

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Anti-ulcer potential of edible mushroom ( Pleurotus pulmo-narius ) on indomethacin-induced gastric ulcer in male wistar rats

Bioactive flavonoids from Populus ciliata : In vitro and In silico evaluation of antimicrobial, antioxidant and anti-inflammatory activities

Isolation and derivatization of bioactive compounds from Saussurea lappa roots with antifungal efficacy against plant pathogenic fungi

Chemical composition and antimicrobial properties of Cymbopogon citratus essential oils against reference strains and pathogens isolated from vaginal and urinary samples

Ethnobotanical uses, biological activities and phytochemistry of mangrove plant species: A review

Fatty acid fractions from Sesbania grandiflora induce apoptosis in MCF-7 human breast cancer cells: A promising anticancer strategy

Anti-ulcer potential of edible mushroom ( Pleurotus pulmo-narius ) on indomethacin-induced gastric ulcer in male wistar rats

Bioactive flavonoids from Populus ciliata : In vitro and In silico evaluation of antimicrobial, antioxidant and anti-inflammatory activities

Isolation and derivatization of bioactive compounds from Saussurea lappa roots with antifungal efficacy against plant pathogenic fungi

Chemical composition and antimicrobial properties of Cymbopogon citratus essential oils against reference strains and pathogens isolated from vaginal and urinary samples