作为美国胸科学会的官方国际在线期刊，美国胸科学会年鉴 (ANNALSATS)，前身为 PATS，提供成人和小儿肺和呼吸睡眠医学以及成人重症监护的最新权威报道。该杂志的范围包括适用于临床实践、临床专家的形成和继续教育以及公共卫生的进步的内容。

The Annals of the American Thoracic Society is the official international online journal of the American Thoracic Society, formerly known as PATS. This journal provides the latest authoritative reports on adult and pediatric pulmonary and sleep medicine, as well as adult critical care. Its scope includes content relevant to clinical practice, the training and continuing education of clinical experts, and advancements in public health.

《Annals of the American Thoracic Society》是美国胸科学会的官方国际在线期刊，前身为PATS。该期刊提供成人和儿童肺部及呼吸睡眠医学，以及成人重症监护领域的最新权威研究。其内容涵盖临床实践、临床专家的培训与继续教育，以及公共卫生的最新进展。

Annals of the American Thoracic Society

Host-microorganism interactions shape local cell functionality, immune responses, and can influence disease development. Evidence indicates that the impact of host-microbe interactions reaches far beyond the local environment, thus influencing responses in peripheral tissues. There is a vital cross-talk between the mucosal tissues of our body, as exemplified by intestinal complications during respiratory disease and vice versa. Although, mechanistically, this phenomenon remains poorly defined, the existence of the gut-lung axis and its implications in both health and disease could be profoundly important for both disease etiology and treatment. In this review, we highlight how changes in the intestinal microenvironment, with a particular focus on the intestinal microbiota, impact upon respiratory disease.

Benjamin J. Marsland

Aurélien Trompette

Eva S. Gollwitzer

Annals ATS

The Gut–Lung Axis in Respiratory Disease

呼吸系统疾病中的肠道-肺轴

Bronchoscopic ablative therapies have been safely and successfully applied for the palliation of malignant central airway obstruction and have the potential for treating inoperable peripheral lung tumors. Proper understanding of technology-tissue interaction allows clinicians to optimize tissue effects, avoid intraoperative complications, predict response to therapy and potential adverse events. This article reviews the basic mechanisms of action and clinical data on bronchoscopic ablation using laser, electrosurgery, photodynamic therapy, cryotherapy, radiofrequency ablation, microwave ablation and thermal vapor ablation for malignant central airway obstruction and peripheral lung tumors.

Udit Chaddha

D. Kyle Hogarth

Septimiu Murgu

Bronchoscopic Ablative Therapies for Malignant Central Airway Obstruction and Peripheral Lung Tumors

恶性中央气道阻塞及周围型肺癌的支气管镜消融治疗

Previous studies have suggested that acute exacerbations of chronic obstructive pulmonary disease (COPD) may be associated with increased risk of myocardial infarction and ischemic stroke.We aimed to quantify the increased risks of myocardial infarction and ischemic stroke risk associated with both moderate and severe acute exacerbation, and to investigate factors that may modify these risks.We performed a self-controlled case series to investigate the rates of myocardial infarction and ischemic stroke after acute exacerbation compared with stable time, within individuals. The participants were 5,696 adults with COPD with a first myocardial infarction (n = 2,850) or ischemic stroke (n = 3,010) and at least one acute exacerbation from the UK Clinical Practice Research Datalink with linked Hospital Episodes Statistics data.The risks of both myocardial infarction and ischemic stroke were increased in the 91 days after an acute exacerbation. The risks were greater after a severe exacerbation (incidence rate ratio [IRR], 2.58; 95% confidence interval [CI], 2.26-2.95 for myocardial infarction; and IRR, 1.97; 95% CI, 1.66-2.33 for ischemic stroke) than after a moderate exacerbation (IRR, 1.58; 95% CI, 1.46-1.71 for myocardial infarction; and IRR, 1.45; 95% CI, 1.33-1.57 for ischemic stroke). The relative risks of myocardial infarction and ischemic stroke associated with acute exacerbation were lower among those with more frequent exacerbations (IRR, 1.42; 95% CI, 1.24-1.62 vs. IRR, 1.69; 95% CI, 1.50-1.91 for myocardial infarction; and IRR, 1.30; 95% CI, 1.15-1.48 vs. IRR, 1.68; 95% CI, 1.50-1.89 for ischemic stroke). Higher GOLD stage was associated with a lower rate of myocardial infarction (IRR, 1.98; 95% CI, 1.61-2.05 vs. IRR, 1.69; 95% CI, 1.45-1.98) but not for ischemic stroke. Aspirin use at baseline was associated with a lower risk of ischemic stroke (IRR, 1.28; 95% CI, 1.10-1.50 vs. IRR, 1.63; 95% CI, 1.47-1.80) but not with myocardial infarction.Acute exacerbations of COPD are associated with an increased risk of myocardial infarction and ischemic stroke within 28 days of their onset. Several patient characteristics were identified that are associated with these events.

Kieran J. Rothnie

Olivia Connell

Hana Müllerová

Liam Smeeth

Neil Pearce

Ian Douglas

Jennifer K. Quint

Myocardial Infarction and Ischemic Stroke after Exacerbations of Chronic Obstructive Pulmonary Disease

慢性阻塞性肺疾病急性加重后心肌梗死和缺血性卒中

Here we describe a microphysiological system that replicates the functional unit of the living human lung. This human “breathing lung-on-a-chip” microdevice provides unique capabilities to reconstitute three-dimensional microarchitecture, dynamic mechanical activity, and integrated physiological function of the alveolar–capillary interface. We demonstrate the potential of this microengineered biomimetic model for screening environmental particulates and modeling complex human disease processes.

Dongeun (Dan) Huh

A Human Breathing Lung-on-a-Chip

一种人体呼吸肺芯片

Christopher Vincent Cosgriff

Leo Anthony Celi

Christopher Martin Sauer

Ann Am Thorac Soc

Boosting Clinical Decision-making: Machine Learning for Intensive Care Unit Discharge.

提升临床决策：机器学习在重症监护病房出院中的应用。

While exposure to air pollution is a known risk factor for adverse pulmonary outcomes, its impact in individuals with idiopathic pulmonary fibrosis (IPF) is less well understood.

Coralynn Sack

Daniel M Wojdyla

Maeve G MacMurdo

Amanda Gassett

Joel D. Kaufman

Ganesh Raghu

Carrie A. Redlich

Peide Li

Amy L. Olson

Thomas B Leonard

Jamie L. Todd

Megan L Neely

Laurie D Snyder

Mridu Gulati

Long-Term Air Pollution Exposure and Severity of Idiopathic Pulmonary Fibrosis: Data from the IPF-PRO Registry

长期空气污染暴露与特发性肺纤维化严重程度：来自IPF-PRO登记库的数据

Numerous studies indicate that preserved ratio impaired spirometry (PRISm) is associated with adverse clinical outcomes. However, the impact of PRISm severity, particularly about FVC, on mortality risk remains unclear.

Yunjoo Im

Taeyun Kim

Jung Hye Hwang

Hyunsoo Kim

Seokmin Hyun

So Rae Kim

Sun Hye Shin

Juhee Cho

Danbee Kang

Hye Yun Park

Association of Preserved Ratio Impaired Spirometry (PRISm) with All-Cause Mortality: A Longitudinal Cohort Study

保留比值受损肺功能（PRISm）与全因死亡率的关联：一项纵向队列研究

Equivocal interstitial lung abnormality (ILA) involves less than 5% of any lung zone or presents unilaterally without satisfying the diagnostic criteria for ILA; however, the prevalence and prognosis of equivocal ILA are unknown.

Ryosuke Imai

Yutaka Tomishima

Tomoaki Nakamura

Daisuke Yamada

Shosei Ro

Clara So

Kohei Okafuji

Atsushi Kitamura

Naoki Nishimura

Torahiko Jinta

Prognosis of Equivocal Interstitial Lung Abnormalities in a Health Check-up Population

健康体检人群中不明确间质性肺异常的预后

Individuals with chronic obstructive pulmonary disease (COPD) in rural areas experience inequitable access to care.

Fernando Picazo

Kevin I. Duan

Travis Hee Wai

Sophia Hayes

Aristotle G. Leonhard

Giuseppe A. Fonseca

Robert Plumley

Kristine A. Beaver

Lucas M. Donovan

David H Au

Laura C Feemster

Rural Residence Associated with Receipt of Recommended Post-Discharge COPD Care among a Cohort of U.S. Veterans

农村居住与美国退伍军人群体中推荐出院后慢性阻塞性肺病护理接受情况的相关性研究

Acetazolamide, eszopiclone, and venlafaxine may target different underlying mechanisms of obstructive sleep apnea (OSA) and individually may partially improve OSA severity in select patients. We tested whether acetazolamide+eszopiclone (DualRx) improves OSA severity. We further explored whether addition of venlafaxine (TripleRx) improves OSA in patients who do not fully respond to DualRx.

Christopher N Schmickl

Jeremy E Orr

Raichel M. Alex

Eli Gruenberg

Gabriela Parra

Stephanie White

Alex Spenceley

Tia DeSarkar

Mitchell Kong

Pamela N DeYoung

Scott A. Sands

Robert L Owens

Atul Malhotra

Combination Drug Therapy with Acetazolamide, Eszopiclone +/- Venlafaxine for Obstructive Sleep Apnea (RESCUE-Combo): A Randomized, Double-blind, Placebo-controlled Trial

乙酰唑胺、艾司佐匹克隆 +/- 文拉法辛联合药物治疗阻塞性睡眠呼吸暂停（RESCUE-Combo）：一项随机、双盲、安慰剂对照试验

短名	Annals ATS
Journal Impact	8.63

ISSN	2325-6621, 2329-6933
h-index	138

出版信息	出版商: American Thoracic Society，出版周期: ，期刊类型: journal，开源期刊: 否
基本数据	创刊年份: 2013，原创研究文献占比: ，自引率:， Gold OA占比:

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