ACS Infectious Diseases is a journal that emphasizes the role of chemistry in this multidisciplinary and collaborative research field. The journal covers a variety of topics, including but not limited to: * Discovery and development of new antibacterial agents—identifying compounds that act synergistically with antibacterial drugs through target-based or phenotypic approaches. * Characterization of drugs and validation of targets or pathways—using single-target and whole-genome knockout and knockdown, biochemical studies, structural biology, and new technologies to facilitate the characterization and prioritization of potential drug targets. * Mechanisms of resistance—basic research that enhances our understanding of resistance; strategies for preventing resistance. * Mechanisms of action—elucidating the mechanisms of clinical and experimental antibacterial agents using genetics, metabolomics, and activity- and affinity-based protein analyses. * Host-pathogen interactions—studying the interactions between host and pathogen, the cell biochemistry of hosts and pathogens, and the molecular interactions between pathogens and host microbiomes. * Small molecule vaccine adjuvants for infectious diseases. * Biochemistry and molecular biology of viruses and bacteria.