DNA abasic sites act as rational therapeutic targets to synergize temozolomide response in both MMR-proficient and deficient cancer

2024-7-9

Editorial: Translational control in cancer

2024-7-9

Ribosome specialization in cancer: a spotlight on ribosomal proteins

2024-7-9

Correction to ‘Ku–DNA binding inhibitors modulate the DNA damage response in response to DNA double-strand breaks’

2024-7-9

Intrinsic PARG inhibitor sensitivity is mimicked by <i>TIMELESS</i> haploinsufficiency and rescued by nucleoside supplementation

2024-7-9

High-level tumour methylation of <i>BRCA1</i> and <i>RAD51C</i> is required for homologous recombination deficiency in solid cancers

2024-7-9

CytoCellDB: a comprehensive resource for exploring extrachromosomal DNA in cancer cell lines

2024-7-9

Decoding ribosome complexity: role of ribosomal proteins in cancer and disease

2024-7-9

The DNA Damage Response (DDR) landscape of endometrial cancer defines discrete disease subtypes and reveals therapeutic opportunities

2024-4-8

<i>FBXO42</i> activity is required to prevent mitotic arrest, spindle assembly checkpoint activation and lethality in glioblastoma and other cancers

2024-4-8

HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

2024-4-8

Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs

2024-4-8

Upstream open reading frames: new players in the landscape of cancer gene regulation

2024-4-8

Non-canonical mRNA translation initiation in cell stress and cancer

2024-4-8

The impact of ribosome biogenesis in cancer: from proliferation to metastasis

2024-4-8

CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers

2024-4-8

Metabolism-dependent secondary effect of anti-MAPK cancer therapy on DNA repair

2024-4-8

Integrated enhancer regulatory network by enhancer–promoter looping in gastric cancer

2024-4-8

Neural-net-based cell deconvolution from DNA methylation reveals tumor microenvironment associated with cancer prognosis

2024-4-8

The shaping of mRNA translation plasticity by RNA G-quadruplexes in cancer progression and therapy resistance

2024-4-8

Next generation sequencing technologies to address aberrant mRNA translation in cancer

2024-4-8

TDP2 is a regulator of estrogen-responsive oncogene expression

2024-4-8

CSDE1: a versatile regulator of gene expression in cancer

2024-3-10

XPA tumor variant leads to defects in NER that sensitize cells to cisplatin

2024-1-9

SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patients

2024-1-9

The impact of tRNA modifications on translation in cancer: identifying novel therapeutic avenues

2024-1-9

Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN

2024-1-9

A large-scale study of peptide features defining immunogenicity of cancer neo-epitopes

2024-1-9

The AsiDNA™ decoy mimicking DSBs protects the normal tissue from radiation toxicity through a DNA-PK/p53/p21-dependent G1/S arrest

2024-1-9

Single-cell genomics analysis reveals complex genetic interactions in an <i>in vivo</i> model of acquired BRAF inhibitor resistance

2024-1-9

Human NTHL1 expression and subcellular distribution determines cisplatin sensitivity in human lung epithelial and non-small cell lung cancer cells

2024-1-9

dbCRAF: a curated knowledgebase for regulation of radiation response in human cancer

2024-1-9

CanVaxKB: a web-based cancer vaccine knowledgebase

2024-1-9

Codelivery of TGFβ and Cox2 siRNA inhibits HCC by promoting T-cell penetration into the tumor and improves response to Immune Checkpoint Inhibitors

2024-1-9

Correction to ‘Translation reprogramming by eIF3 linked to glioblastoma resistance’

2024-1-9

TSCRE: a comprehensive database for tumor-specific <i>cis</i>-regulatory elements

2024-1-9

How snoRNAs can contribute to cancer at multiple levels

2024-1-9

METTL3 as a master regulator of translation in cancer: mechanisms and implications

2024-1-9

Singleton mutations in large-scale cancer genome studies: uncovering the tail of cancer genome

2024-1-9

Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma

2024-1-9

The ORFIUS complex regulates ORC2 localization at replication origins

2024-1-9

Emerging roles of the CIP2A–TopBP1 complex in genome integrity

2023-10-11

m6A epitranscriptome analysis reveals differentially methylated transcripts that drive early chemoresistance in bladder cancer

2023-10-11

Detection of oxaliplatin- and cisplatin-DNA lesions requires different global genome repair mechanisms that affect their clinical efficacy

2023-10-11

Gene essentiality in cancer is better predicted by mRNA abundance than by gene regulatory network-inferred activity

2023-10-11

Pan-cancer analysis of promoter activity quantitative trait loci

2023-10-11

Single-cell transcriptomics reveals long noncoding RNAs associated with tumor biology and the microenvironment in pancreatic cancer

2023-10-11

An impaired ubiquitin-proteasome system increases APOBEC3A abundance

2023-10-11

Co-evolution of <i>AR</i> gene copy number and structural complexity in endocrine therapy resistant prostate cancer

2023-6-9

Heterogeneity in the gene regulatory landscape of leiomyosarcoma

2023-6-9