The impact of multi-omics in medicine

2024-9-1

Omics-based discoveries guiding personalized medicine

2024-9-1

Decoding the pathogenesis of spermatogenic failure in cryptorchidism through single-cell transcriptomic profiling

2024-9-1

Early-onset cancers: Biological bases and clinical implications

2024-9-1

Mother’s milk microbiota is associated with the developing gut microbial consortia in very-low-birth-weight infants

2024-9-1

CMG901, a Claudin18.2-specific antibody-drug conjugate, for the treatment of solid tumors

2024-9-1

Risk assessment with gene expression markers in sepsis development

2024-9-1

Reconstruction of patient-specific confounders in AI-based radiologic image interpretation using generative pretraining

2024-9-1

mRNA-delivery of IDO1 suppresses T cell-mediated autoimmunity

2024-9-1

Detecting altered hepatic lipid oxidation by MRI in an animal model of MASLD

2024-9-1

Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD

2024-9-1

Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation

2024-9-1

Integrating multi-omics to unravel host-microbiome interactions in inflammatory bowel disease

2024-9-1

Clinical-transcriptional prioritization of the circulating proteome in human heart failure

2024-9-1

Five miRNAs identified in fucosylated extracellular vesicles as non-invasive diagnostic signatures for hepatocellular carcinoma

2024-9-1

Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury

2024-9-1

Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma

2024-9-1

Proteomic landscape profiling of primary prostate cancer reveals a 16-protein panel for prognosis prediction.

2024-8-20

Combining gemcitabine and MSC delivering soluble TRAIL to target pancreatic adenocarcinoma and its stroma.

2024-8-20

HSD3B1 genotype and outcomes in metastatic hormone-sensitive prostate cancer with androgen deprivation therapy and enzalutamide: ARCHES.

2024-8-20

A core proteome profile unites mouse models and patients in Alzheimer disease.

2024-8-20

The complex molecular epileptogenesis landscape of glioblastoma.

2024-8-20

The effect of SGLT2 inhibition on prostate cancer: Mendelian randomization and observational analysis using electronic healthcare and cohort data.

2024-8-20

Machine learning-based analysis identifies and validates serum exosomal proteomic signatures for the diagnosis of colorectal cancer.

2024-8-20

Camu-camu decreases hepatic steatosis and liver injury markers in overweight, hypertriglyceridemic individuals: A randomized crossover trial.

2024-8-20

A pan-cancer screen identifies drug combination benefit in cancer cell lines at the individual and population level.

2024-8-20

Targeting miR-29 mitigates skeletal senescence and bolsters therapeutic potential of mesenchymal stromal cells.

2024-8-20

The SGLT2 inhibitor dapagliflozin ameliorates renal fibrosis in hyperuricemic nephropathy.

2024-8-20

Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8

2024-8-20

TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function

2024-8-1

Next-generation lung cancer pathology: Development and validation of diagnostic and prognostic algorithms

2024-8-1

Robust SARS-CoV-2-neutralizing antibodies sustained through 6 months post XBB.1.5 mRNA vaccine booster

2024-8-1

Impact of antimicrobials on penile HIV susceptibility and immunology in uncircumcised men: A randomized phase 1/2 clinical trial

2024-8-1

Human milk microbiota, oligosaccharide profiles, and infant gut microbiome in preterm infants diagnosed with necrotizing enterocolitis

2024-8-1

Transformer-based AI technology improves early ovarian cancer diagnosis using cfDNA methylation markers

2024-8-1

A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis

2024-8-1

CTC-derived pancreatic cancer models serve as research tools and are suitable for precision medicine approaches

2024-8-1

Spatial transcriptomic validation of a biomimetic model of fibrosis enables re-evaluation of a therapeutic antibody targeting LOXL2

2024-8-1

Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization

2024-8-1

Phase 1a study of ESG401, a Trop2 antibody-drug conjugate, in patients with locally advanced/metastatic solid tumors

2024-8-1

Decoupling HIV-1 antiretroviral drug inhibition from plasma antibody activity to evaluate broadly neutralizing antibody therapeutics and vaccines

2024-8-1

Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors

2024-8-1

A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib

2024-8-1

SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2

2024-8-1

Advanced glycation end products mediate biomineralization disorder in diabetic bone disease

2024-8-1

β-resorcylic acid released by Limosilactobacillus reuteri protects against cisplatin-induced ovarian toxicity and infertility

2024-8-1

Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT

2024-8-1

Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma

2024-8-1

Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis

2024-8-1

In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma

2024-8-1