ACS Bio & Med Chem Au is an open access journal that covers all aspects of biological and medicinal chemistry, publishing short letters, comprehensive articles, reviews, and perspectives. We welcome studies that provide fundamental insights or describe novel syntheses, as well as clinical or other application-based work. The journal's scope includes experimental and theoretical studies on the chemical, physical, mechanistic, and/or structural basis of biological or cellular functions across all domains of life. It encompasses fields such as chemical biology, synthetic biology, disease biology, cell biology, agriculture and food, natural products research, nucleic acid biology, neuroscience, structural biology, and biophysics.\n\nThe journal focuses on research directions including: \n- Medicinal chemistry, encompassing compound design and optimization, biological evaluation, molecular mechanistic understanding of drug delivery and drug delivery systems, imaging agents, and the pharmacology and translational science of both small and large bioactive molecules. \n- Novel computational, cheminformatics, and structural studies for the identification (or structure-activity relationship analysis) of bioactive molecules, ligands, and their targets. \n- Computational studies applying established computational methods, but only in combination with novel and original experimental data (e.g., in cases where new compounds have been designed and tested). \n- Research related to infectious diseases, including pathogens, host-pathogen interactions, therapeutics, diagnostics, vaccines, drug delivery systems, and other biomedical technology development pertaining to infectious diseases.