Clinical Obesity is an international peer-reviewed journal publishing high quality translational and clinical research papers and reviews focussing on obesity and its co-morbidities.    Key areas of interest are:    • Patient assessment, classification, diagnosis and prognosis  • Drug treatments, clinical trials and supporting research  • Bariatric surgery and follow-up issues  • Surgical approaches to remove body fat  • Pharmacological, dietary and behavioural approaches for weight loss  • Clinical physiology  • Clinically relevant epidemiology  • Psychological aspects of obesity  • Co-morbidities  • Nursing and care of patients with obesity.

Clinical Obesity is an international peer-reviewed journal that publishes high-quality translational and clinical research papers and reviews focusing on obesity and its comorbidities. Key areas of interest include: • Patient assessment, classification, diagnosis, and prognosis • Drug treatments, clinical trials, and supporting research • Bariatric surgery and follow-up issues • Surgical approaches to remove body fat • Pharmacological, dietary, and behavioral approaches for weight loss • Clinical physiology • Clinically relevant epidemiology • Psychological aspects of obesity • Comorbidities • Nursing and care of patients with obesity.

《Clinical Obesity》是一本国际同行评审的期刊，致力于发表高质量的转化医学和临床研究论文以及关于肥胖及其相关疾病的综述。期刊关注的主要领域包括：• 患者评估、分类、诊断和预后 • 药物治疗、临床试验及相关研究 • 减肥手术及其后续问题 • 移除体脂的外科方法 • 药物、饮食和行为干预的减重策略 • 临床生理学 • 相关流行病学 • 肥胖的心理学因素 • 相关疾病 • 肥胖患者的护理与照顾。

Clinical Obesity

Literature evaluating the relationship between central obesity and cognitive deficits in type 2 diabetes (T2DM) remains scarce. This cross-sectional analysis explored the association of novel and traditional central obesity measures with cognitive performance in older (aged ≥60 years) non-demented multi-ethnic Asians with T2DM, including a stratified analysis by body mass index (BMI). Cognitive function was assessed using the Repeatable Battery for the Assessment of Neuropsychological Status. Central obesity measures including visceral fat area (VFA), waist circumference, waist:hip ratio, waist:height ratio, abdominal volume index, body roundness index and conicity index were measured and/or computed. In our cohort (N = 677; mean age = 67 ± 5 years, 51.7% men), VFA emerged as an associate of overall cognitive performance after covariate adjustment and Bonferroni correction (β = -.10, 95% CI = -0.18, -0.03), outperforming the other adiposity indices. Specifically, VFA was inversely associated with delayed memory and language scores. Additionally, compared with normal-weight individuals, excess visceral obesity (VFA ≥100 cm2 ) was independently associated with lower cognitive scores to a greater extent in normal BMI (<23 kg/m2 ) adults than in those with high BMI (≥23 kg/m2 ). Assessment and management of visceral adiposity may help to prevent cognitive decline in older people with T2DM, and reduce the global burden of dementia in ageing populations.

Mei Chung Moh

Serena Low

Tze Pin Ng

Jiexun Wang

Su Fen Ang

Clara Tan

Keven Ang

Subramaniam Tavintharan

Chee Fang Sum

Pek Yee Kwan

Simon Biing Ming Lee

Wern Ee Tang

Su Chi Lim

Association of traditional and novel measures of central obesity with cognitive performance in older multi‐ethnic Asians with type 2 diabetes

传统与新型中心性肥胖指标与2型糖尿病老年多民族亚洲人认知表现的相关性

Biliopancreatic diversion with duodenal switch (BPD-DS) and single anastomosis duodeno-ileostomy with sleeve (SADI-S) are associated with superior and sustained weight loss outcomes. Despite their growing popularity, long-term safety profiles, particularly the risk of internal hernia (IH), remain underexplored. This study aimed to evaluate the incidence and characteristics of IH following BPD-DS and SADI-S procedures, comparing their clinical presentation, diagnostic methods, and outcomes. A retrospective chart review was performed for patients who underwent BPD-DS or SADI-S between 2008 and 2023 in two high-volume tertiary referral centres for bariatric surgery in the United States. Demographic data, comorbidities, operative details, and follow-up outcomes were collected. A subgroup analysis of IH cases was conducted to compare the incidence, location of hernias, and diagnostic modalities between procedures. Out of 1160 patients (85.1% BPD-DS; 14.9% SADI-S), the overall incidence of IH was 1.12%, with a higher rate in BPD-DS (0.8%) than in SADI-S (0.57%). Most IHs occurred within the first 24 months postoperatively. The majority of IHs in BPD-DS patients were in the pseudo-Petersen's space. The single IH case in the SADI-S group occurred in the same space. Most patients presented with abdominal pain and were diagnosed by CT imaging. SADI-S showed a lower IH rate compared to BPD-DS, but further studies are needed to confirm these findings. The variability in clinical presentation complicates the diagnosis of IH, emphasizing the need for increased clinical vigilance.

Romulo P. Lind

Graziella Galvao Goncalves

Amanda Belluzzi

Karl Hage

Juliana Antunes

Muhammad Ghanem

Muhammad A. Jawad

Michael Kendrick

Omar M. Ghanem

Andre F. Teixeira

Internal hernia in patients after duodenal switch: A multi‐centred comparative analysis

十二指肠转位术后患者的内疝：一项多中心比较分析

Summary This study addresses the diagnostic challenges of identifying lymphoedema in patients with lipoedema using lymphoscintigraphy. Overdiagnosis of lymphoedema in this patient population is frequent and may result in reduced proposed surgical interventions. We retrospectively analyzed clinical data from patients followed for lipoedema, lymphoedema or lipolymphoedema and who underwent lymphoscintigraphy. All patients were assigned a clinical or lymphoscintigraphic diagnosis of lymphoedema and concordance between clinical and lymphoscintigraphic diagnosis was assessed. A modification of lymphoscintigraphic criteria interpretation was proposed to enhance the diagnosis specificity. We included 94 female patients (188 lower limbs). One hundred and thirty‐seven limbs presented with signs of lipoedema (137/188; 72.9%) and 42 with clinical signs of lymphoedema (42/188; 22.3%). Overall, 125 limbs presented with a diagnosis of lymphoedema on lymphoscintigraphy (125/188; 66.5%). Using lymphoscintigraphy to diagnose lymphoedema in patients with lipoedema resulted in low specificity (38.3%). By adjusting the interpretation criteria of the lymphoscintigraphic anomalies, we could achieve a specificity of 80.85%, reducing the risk of overdiagnosing lymphoedema in patients with lipoedema. This study contributes to the ongoing efforts to optimize the assessment and management of patients with lipoedema and potential lymphatic involvement, by modifying the interpretation of lymphoscintigraphic criteria.

Hadrien Amiel

Julien Coulie

Raphaël Georis

Raquel van la Parra

Genevieve Pirson

Christine Deconinck

Enhancing lymphoscintigraphic specificity of lymphoedema diagnosis in patients with lipoedema

提高脂水肿患者淋巴水肿诊断的淋巴闪烁显像特异性

Summary Metabolic and bariatric surgeries (MBS), including Roux‐en‐Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG), have proven effective in promoting long‐term diabetes remission among patients with type‐2 diabetes (T2D). In this multicentre retrospective cohort study, we investigated the effectiveness of RYGB and SG in achieving diabetes remission, specifically among patients with T2D and vascular complications, while accounting for similar baseline diabetes severity. Although various scores predict diabetes remission after bariatric surgery, they do not consider diabetes‐related vascular complications, which can influence outcomes even in patients with similar baseline T2D severity. We collected preoperative data on microvascular (retinopathy, nephropathy, neuropathy) and macrovascular comorbidities (coronary artery disease, cerebrovascular accidents, peripheral artery disease) to compare the efficacy of RYGB and SG. Among 961 patients analysed, those with vascular complications showed higher remission rates with RYGB (OR: 1.97) compared to SG, despite similar baseline diabetes severity. Notably, RYGB patients with microvascular complications had a significant advantage in achieving T2D remission (OR: 2.95). However, no significant differences in remission were observed in patients with macrovascular complications. These findings suggest that RYGB may be more effective than SG in specific patient populations, particularly those with microvascular complications, emphasizing the need for personalized treatment strategies.

Wissam Ghusn

Pearl Ma

Kayla Ikemiya

Marita Salame

Kamal Abi Mosleh

Andrew C. Storm

Barham K. Abu Dayyeh

Kelvin Higa

Comparative effectiveness of Roux‐en‐Y gastric bypass and sleeve gastrectomy in achieving diabetes remission in patients with diabetes‐related vascular diseases: A multicentred study

Roux-en-Y胃旁路术与袖状胃切除术在糖尿病相关血管疾病患者中实现糖尿病缓解的比较效果：一项多中心研究

Summary Global obesity rates have risen dramatically, now exceeding deaths from starvation. Metabolic and bariatric surgery (MBS), initially for severe obesity (BMI ≥35 kg/m 2 ), is performed globally over 500 000 times annually, offering significant metabolic benefits beyond weight loss. However, varying eligibility criteria globally impact patient care and healthcare resources. Updated in 2022, ASMBS and IFSO guidelines aim to standardise MBS indications, reflecting current understanding and emphasising comprehensive preoperative assessments. Yet, clinical variability persists, necessitating consensus‐based recommendations. This modified Delphi study engaged 45 global experts to establish consensus on perioperative management in MBS. Experts selected from bariatric societies possessed expertise in MBS and participated in a two‐round Delphi protocol. Consensus was achieved on 90 of 169 statements (53.3%), encompassing multidisciplinary team composition, patient selection criteria, preoperative testing, and referral pathways. The agreement highlighted the critical role of comprehensive preoperative assessments and the integration of healthcare professionals in MBS. These findings offer essential insights to standardise perioperative practices and advocate for evidence‐based guidelines in MBS globally. The study underscores the need for unified protocols to optimise outcomes and guide future research in MBS.

Danielle R. Clyde

Reza Adib

Sarfaraz Baig

Aparna G. Bhasker

James Byrne

David Cameron

Copaescu Catalain

Ken Clare

Andrew de Beaux

Gillian Drummond

Hayssam Fawal

Martin Fried

Omar Ghanem

Yitka Graham

Ramen Goel

George Hopkins

Farah Husain

Brian Joyce

Mohammad Kermansaravi

Shanu Kothari

Lilian Kow

Silvia Leite

Brij Madhok

David Mahon

Karl Miller

Alex Miras

Osama Moussa

Manoel G. Neto

Abdelrahman Nimeri

Mary O'Kane

Chetan Parmar

Ralph Peterli

Luis Poggi

Paulina Saliminen

Rupa Sarkar

Jon Shenfine

Stephanie Sogg

Erik Stenberg

Michel Suter

Safwan Taha

Abd Tahrani

Ramon Vilallonga

Kelvin Voon

Richard Welbourn

Carlos Zerrweck

Peter Lamb

Kamal K. Mahawar

Wah Yang

Andrew G. N. Robertson

An international Delphi consensus on patient preparation for metabolic and bariatric surgery

代谢和减重手术患者准备的国际德尔菲共识

Summary This study aims to give a comprehensive overview of the one anastomosis gastric bypass (OAGB) and Roux‐en‐Y gastric bypass (RYGB) during 5 years of follow‐up in terms of weight loss, the remission of obesity‐associated diseases and complications. We performed a retrospective cohort study, with a 1:1 propensity‐score matched (PSM) comparison between all adult patients who underwent a primary OAGB or RYGB in 2016. Patients with a body mass index (BMI) ≥50 kg/m 2 were excluded. In total, 372 patients underwent OAGB and 113 patients RYGB. After performing a 1:1 PSM, we obtained two nearly identical cohorts of 113 patients. After OAGB, the percentage of total weight loss (%TWL) was significantly higher during 5 years of follow‐up. Also, more patients after OAGB had a successful weight loss (TWL &gt; 20%) after 5 years (86% vs. 72%; p = .019). The remission of obesity‐associated diseases and short‐term complications did not differ between both procedures. Persistent reflux was the reason for conversion to RYGB in 11.3% of the patients after OAGB. More internal herniations were seen after RYGB (10.4% vs. 1.9%; p = .010). Overall, the proportion of patients with major mid‐term complications did not differ between both procedures. In conclusion, OAGB resulted in more weight reduction and especially fewer patients with insufficient weight loss during 5 years of follow‐up, while remission of obesity‐associated diseases remained the same.

Lindsy van der Laan

Dionne Sizoo

Loek J. M. de Heide

André P. van Beek

Marloes Emous

Fewer patients with insufficient weight loss after one anastomosis gastric bypass compared to Roux‐en‐Y gastric bypass after 5 years of follow‐up

与 Roux-en-Y 胃旁路术相比，接受单吻合口胃旁路术的患者在 5 年随访后体重未达标的人数更少

The endocrine consequences of weight loss by bariatric surgery (BS) and caloric restriction are not fully understood but contribute to variable improvements in insulin sensitivity and cardiometabolic health. This study compared changes in insulin sensitivity and plasma concentrations of gut peptides 8 weeks and 1 year after BS and a low-calorie diet (LCD). Nineteen female patients with obesity self-selected BS (gastric bypass [n = 5] or sleeve gastrectomy [n = 7]) or LCD (n = 7) in this parallel-arm, prospective observational study. We assessed insulin sensitivity via a two-step hyperinsulinemic-euglycemic clamp (20 and 80 mU/min/m

Adam C. Lowe

Dorien Reijnders

Charmaine S. Tam

Leanne M. Redman

Robbie Beyl

Karl A. LeBlanc

Mark G. Hausmann

Vance L. Albaugh

Frank L. Greenway

Eric Ravussin

Changes in insulin sensitivity and gut peptides 8 and 52 weeks after bariatric surgery or low‐calorie diet

减重手术或低热量饮食后8周和52周胰岛素敏感性和肠道肽的变化

Abbreviation	Clin. Obes.
Journal Impact	2.16
Quartiles(Global)	ENDOCRINOLOGY & METABOLISM(Q3)

ISSN	1758-8103, 1758-8111
h-index	35

Publication Information	Publisher: John Wiley & Sons Inc.，Publishing cycle: ，Journal Type: journal，Open Access Journals: No
Basic data	Year of publication: 2014，Proportion of original research papers: 73.68%，Self Citation Rate:4.50%， Gold OA Rate: 34.48%

Clinical Obesity

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Association of traditional and novel measures of central obesity with cognitive performance in older multi‐ethnic Asians with type 2 diabetes

Internal hernia in patients after duodenal switch: A multi‐centred comparative analysis

Enhancing lymphoscintigraphic specificity of lymphoedema diagnosis in patients with lipoedema

Comparative effectiveness of Roux‐en‐Y gastric bypass and sleeve gastrectomy in achieving diabetes remission in patients with diabetes‐related vascular diseases: A multicentred study

An international Delphi consensus on patient preparation for metabolic and bariatric surgery

Comparative effectiveness of Roux‐en‐Y gastric bypass and sleeve gastrectomy in achieving diabetes remission in patients with diabetes‐related vascular diseases: A multicentred study

Enhancing lymphoscintigraphic specificity of lymphoedema diagnosis in patients with lipoedema

Internal hernia in patients after duodenal switch: A multi‐centred comparative analysis

Fewer patients with insufficient weight loss after one anastomosis gastric bypass compared to Roux‐en‐Y gastric bypass after 5 years of follow‐up

Changes in insulin sensitivity and gut peptides 8 and 52 weeks after bariatric surgery or low‐calorie diet