The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is one of the world's leading journals in tropical medicine, publishing original scientific articles and covering the latest scientific research, with a focus on the application of techniques in areas such as population studies, clinical and laboratory sciences, tropical medicine, parasitology, and immunology. The journal addresses topics including infectious diseases, epidemiology, basic and molecular biology, virology, and international medicine. It publishes unsolicited peer-reviewed manuscripts, review articles, brief reports, images in clinical tropical medicine, case studies, reports on the efficacy of new drugs and treatments, prevention and control methods, new diagnostic methods and devices, book reviews, and letters to the editor. The subject matter ranges from applied epidemiology related to diseases like AIDS to the molecular biology of vaccine development. The journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists, and public health officials who focus on health issues in tropical regions and developing countries, as well as researchers studying emerging infectious diseases. Major funding agencies, including charities and government organizations active in public health, as well as medical and scientific libraries worldwide, subscribe to the journal. Each year, two or more supplements on topics of special interest are published, representing comprehensive and multidisciplinary discussions on issues of concern to tropical disease experts and health problems in developing countries.